Polyacrilic Acid and Chitosan Assisted Solvothermal Synthesis of Up-converting NaYF4: Yb,Er Particles
Abstract
There is a growing interest for development of a facile and reproducible approach for the synthesis of biocompatible lanthanide doped up-converting nanoparticles (UCNPs) for deep tissue imaging and targeted drug delivery. Synthesis of such particles is usually performed through the decomposition of organometallic compounds, followed either with a ligands exchange or with a biocompatible layer coating. In this work, biocompatible NaYF4:Yb,Er (17 mol% Yb; 3 mol% Er) nanoparticles were synthesized by one-pot hydrothermal processing with an assistance of chitosan (Ch) or polyacrylic acid (PAA). Obtained powders were analyzed by X-ray powder diffraction (XRPD, Bruker D8 Discovery), field emission scanning electron microscopy (FE-SEM, Zeiss, DSM 960), transmission electron microscopy (TEM, JEOL JEM 2010), Fourier transform infrared (FTIR, Thermo Scientific Nicolet 6700) and photoluminescence (PL, Spex Fluorolog with C31034 cooled photomultiplier) spectroscopy. The results showed that althou...gh both powders crystallize in the same crystal arrangement (cubic, Fm-3m), particles size, shape and optical properties are dependent on the polymer used.
Keywords:
up-conversion / solvothermal synthesis / chitosan / NaYF4:Yb,Er / polyacrylic acidSource:
Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructu, 2018, 195-197Publisher:
- Belgrade : Serbian Academy of Sciences and Arts
Funding / projects:
- Rational design and synthesis of biologically active and coordination compounds and functional materials, relevant for (bio)nanotechnology (RS-MESTD-Basic Research (BR or ON)-172035)
Institution/Community
Tehnološko-metalurški fakultetTY - CONF AU - Mančić, Lidija AU - Nikolić, Marko G. AU - Rabasović, Mihailo D. AU - Milošević, Olivera B. PY - 2018 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3768 AB - There is a growing interest for development of a facile and reproducible approach for the synthesis of biocompatible lanthanide doped up-converting nanoparticles (UCNPs) for deep tissue imaging and targeted drug delivery. Synthesis of such particles is usually performed through the decomposition of organometallic compounds, followed either with a ligands exchange or with a biocompatible layer coating. In this work, biocompatible NaYF4:Yb,Er (17 mol% Yb; 3 mol% Er) nanoparticles were synthesized by one-pot hydrothermal processing with an assistance of chitosan (Ch) or polyacrylic acid (PAA). Obtained powders were analyzed by X-ray powder diffraction (XRPD, Bruker D8 Discovery), field emission scanning electron microscopy (FE-SEM, Zeiss, DSM 960), transmission electron microscopy (TEM, JEOL JEM 2010), Fourier transform infrared (FTIR, Thermo Scientific Nicolet 6700) and photoluminescence (PL, Spex Fluorolog with C31034 cooled photomultiplier) spectroscopy. The results showed that although both powders crystallize in the same crystal arrangement (cubic, Fm-3m), particles size, shape and optical properties are dependent on the polymer used. PB - Belgrade : Serbian Academy of Sciences and Arts C3 - Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructu T1 - Polyacrilic Acid and Chitosan Assisted Solvothermal Synthesis of Up-converting NaYF4: Yb,Er Particles EP - 197 SP - 195 UR - https://hdl.handle.net/21.15107/rcub_technorep_3768 ER -
@conference{ author = "Mančić, Lidija and Nikolić, Marko G. and Rabasović, Mihailo D. and Milošević, Olivera B.", year = "2018", abstract = "There is a growing interest for development of a facile and reproducible approach for the synthesis of biocompatible lanthanide doped up-converting nanoparticles (UCNPs) for deep tissue imaging and targeted drug delivery. Synthesis of such particles is usually performed through the decomposition of organometallic compounds, followed either with a ligands exchange or with a biocompatible layer coating. In this work, biocompatible NaYF4:Yb,Er (17 mol% Yb; 3 mol% Er) nanoparticles were synthesized by one-pot hydrothermal processing with an assistance of chitosan (Ch) or polyacrylic acid (PAA). Obtained powders were analyzed by X-ray powder diffraction (XRPD, Bruker D8 Discovery), field emission scanning electron microscopy (FE-SEM, Zeiss, DSM 960), transmission electron microscopy (TEM, JEOL JEM 2010), Fourier transform infrared (FTIR, Thermo Scientific Nicolet 6700) and photoluminescence (PL, Spex Fluorolog with C31034 cooled photomultiplier) spectroscopy. The results showed that although both powders crystallize in the same crystal arrangement (cubic, Fm-3m), particles size, shape and optical properties are dependent on the polymer used.", publisher = "Belgrade : Serbian Academy of Sciences and Arts", journal = "Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructu", title = "Polyacrilic Acid and Chitosan Assisted Solvothermal Synthesis of Up-converting NaYF4: Yb,Er Particles", pages = "197-195", url = "https://hdl.handle.net/21.15107/rcub_technorep_3768" }
Mančić, L., Nikolić, M. G., Rabasović, M. D.,& Milošević, O. B.. (2018). Polyacrilic Acid and Chitosan Assisted Solvothermal Synthesis of Up-converting NaYF4: Yb,Er Particles. in Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructu Belgrade : Serbian Academy of Sciences and Arts., 195-197. https://hdl.handle.net/21.15107/rcub_technorep_3768
Mančić L, Nikolić MG, Rabasović MD, Milošević OB. Polyacrilic Acid and Chitosan Assisted Solvothermal Synthesis of Up-converting NaYF4: Yb,Er Particles. in Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructu. 2018;:195-197. https://hdl.handle.net/21.15107/rcub_technorep_3768 .
Mančić, Lidija, Nikolić, Marko G., Rabasović, Mihailo D., Milošević, Olivera B., "Polyacrilic Acid and Chitosan Assisted Solvothermal Synthesis of Up-converting NaYF4: Yb,Er Particles" in Program and Book of Abstracts / First International Conference on Electron Microscopy of Nanostructu (2018):195-197, https://hdl.handle.net/21.15107/rcub_technorep_3768 .