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dc.creatorMijatović, Tamara
dc.creatorPerić, Milica
dc.creatorMatović, Luka
dc.creatorRistović, Marija
dc.creatorDrmanić, Saša
dc.date.accessioned2021-03-10T13:36:35Z
dc.date.available2021-03-10T13:36:35Z
dc.date.issued2018
dc.identifier.issn1840-4774
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/3779
dc.description.abstractSix ester and amide derivates of 2,6-dimethyl-4-(substituted)-1,4-dihydropyridine-3,5-dicarboxylic acid have been synthesized in this paper, including: diethyl 2,6-dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate, diethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, diethyl 2,6-dimethyl-4-(4-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate, diethyl 4-(2-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate, diethyl 4-(3-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate and diethyl 4-(4-hydroxyphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate. Obtained ester derivates were used afterwards as a starting compounds for synthesis of amide derivates, including: 2,6-dimethyl-4-phenyl-N3,N5-di(thiazol-2-yl)-1,4-dihydropyridine-3,5-dicarboxamide, 2,6-dimethyl-4-(3-nitrophenyl)-N3,N5-di(thiazol-2-yl)-1,4-dihydropyridine-3,5-dicarboxamide, 2,6-dimethyl-4-(4-nitrophenyl)-N3,N5-di(thiazol-2-yl)-1,4-dihydropyridine-3,5-dicarboxamide, 4-(2-hydroxyphenyl)-2,6-dimethyl-N3,N5-di(thiazol-2-yl)-1,4-dihydropyridine-3,5-dicarboxamide, 4-(3-hydroxyphenyl)-2,6-dimethyl-N3,N5-di(thiazol-2-yl)-1,4-dihydropyridine-3,5-dicarboxamide and 4-(4-hydroxyphenyl)-2,6-dimethyl-N3,N5-di(thiazol-2-yl)-1,4-dihydropyridine-3,5-dicarboxamide. Obtained compounds were characterized by melting point, elementary analysis and FT-IR spectroscopy. In order to determine the effect of the substituent, the antioxidative activity assay of obtained 1,4-dihydropyridines was performed by using the DPPH (1,1-diphenyl-2-picryl-hydrazyl) free radical scavenging method.en
dc.publisherUniversity of East Sarajevo, Faculty of Technology
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceJournal of Engineering & Processing Management
dc.titleSinteza, karakterizacija i ispitivanje antioksidativne aktivnosti estarskih i amidnih derivata 2,6-dimetil-4-supstituisane-1,4-dihidropiridin-3,5-dikarboksilne kiselineen
dc.typearticle
dc.rights.licenseBY-NC-ND
dc.citation.epage15
dc.citation.issue2
dc.citation.other10(2): 8-15
dc.citation.spage8
dc.citation.volume10
dc.identifier.doi10.7251/JEPM181002008M
dc.identifier.fulltexthttp://TechnoRep.tmf.bg.ac.rs/bitstream/id/1596/3776.pdf
dc.identifier.rcubDOAJ-159
dc.type.versionpublishedVersion


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