Development of material with strong antimicrobial activity by high pressure CO2 impregnation of polyamide nanofibers with thymol
Само за регистроване кориснике
2018
Аутори
Marković, DarkaMilovanović, Stoja
De Clerck, Karen
Žižović, Irena
Stojanović, Dušica
Radetić, Maja
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
This study discusses the potential of high pressure (supercritical and liquid) CO2 impregnation to load electrospun polyamide nanofibers with thymol as an antimicrobial agent. The influence of selected pressures and temperatures on the thymol impregnation yield has been evaluated. High pressure impregnation provided superior thymol impregnation yields (up to similar to 60%) on nanofibers compared to conventional immersion methods (similar to 2%). The presence of thymol in impregnated samples was confirmed by FT-IR analysis. FESEM analysis revealed that impregnation with thymol resulted in a swelling of the nanofibers. The nanofiber morphological changes strongly depended on the thymol impregnation yield. Nanofibers impregnated with thymol using high pressure CO2 ensured excellent antimicrobial activity against Gram-negative bacterium E. coli, Gram-positive bacterium S. aureus and fungus C. albicans. In addition, the Higuchi release model well fitted the thymol release studies.
Кључне речи:
Polyamide nanofibers / Supercritical carbon dioxide / Impregnation / Antimicrobial activity / Thymol releaseИзвор:
Journal of CO2 Utilization, 2018, 26, 19-27Издавач:
- Elsevier Sci Ltd, Oxford
Финансирање / пројекти:
- Функционални физиолошки активни биљни материјали са додатом вредношћу за примену у фармацеутској и прехрамбеној индустрији (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45017)
DOI: 10.1016/j.jcou.2018.04.019
ISSN: 2212-9820
WoS: 000439069700003
Scopus: 2-s2.0-85046036679
Колекције
Институција/група
Tehnološko-metalurški fakultetTY - JOUR AU - Marković, Darka AU - Milovanović, Stoja AU - De Clerck, Karen AU - Žižović, Irena AU - Stojanović, Dušica AU - Radetić, Maja PY - 2018 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3889 AB - This study discusses the potential of high pressure (supercritical and liquid) CO2 impregnation to load electrospun polyamide nanofibers with thymol as an antimicrobial agent. The influence of selected pressures and temperatures on the thymol impregnation yield has been evaluated. High pressure impregnation provided superior thymol impregnation yields (up to similar to 60%) on nanofibers compared to conventional immersion methods (similar to 2%). The presence of thymol in impregnated samples was confirmed by FT-IR analysis. FESEM analysis revealed that impregnation with thymol resulted in a swelling of the nanofibers. The nanofiber morphological changes strongly depended on the thymol impregnation yield. Nanofibers impregnated with thymol using high pressure CO2 ensured excellent antimicrobial activity against Gram-negative bacterium E. coli, Gram-positive bacterium S. aureus and fungus C. albicans. In addition, the Higuchi release model well fitted the thymol release studies. PB - Elsevier Sci Ltd, Oxford T2 - Journal of CO2 Utilization T1 - Development of material with strong antimicrobial activity by high pressure CO2 impregnation of polyamide nanofibers with thymol EP - 27 SP - 19 VL - 26 DO - 10.1016/j.jcou.2018.04.019 ER -
@article{ author = "Marković, Darka and Milovanović, Stoja and De Clerck, Karen and Žižović, Irena and Stojanović, Dušica and Radetić, Maja", year = "2018", abstract = "This study discusses the potential of high pressure (supercritical and liquid) CO2 impregnation to load electrospun polyamide nanofibers with thymol as an antimicrobial agent. The influence of selected pressures and temperatures on the thymol impregnation yield has been evaluated. High pressure impregnation provided superior thymol impregnation yields (up to similar to 60%) on nanofibers compared to conventional immersion methods (similar to 2%). The presence of thymol in impregnated samples was confirmed by FT-IR analysis. FESEM analysis revealed that impregnation with thymol resulted in a swelling of the nanofibers. The nanofiber morphological changes strongly depended on the thymol impregnation yield. Nanofibers impregnated with thymol using high pressure CO2 ensured excellent antimicrobial activity against Gram-negative bacterium E. coli, Gram-positive bacterium S. aureus and fungus C. albicans. In addition, the Higuchi release model well fitted the thymol release studies.", publisher = "Elsevier Sci Ltd, Oxford", journal = "Journal of CO2 Utilization", title = "Development of material with strong antimicrobial activity by high pressure CO2 impregnation of polyamide nanofibers with thymol", pages = "27-19", volume = "26", doi = "10.1016/j.jcou.2018.04.019" }
Marković, D., Milovanović, S., De Clerck, K., Žižović, I., Stojanović, D.,& Radetić, M.. (2018). Development of material with strong antimicrobial activity by high pressure CO2 impregnation of polyamide nanofibers with thymol. in Journal of CO2 Utilization Elsevier Sci Ltd, Oxford., 26, 19-27. https://doi.org/10.1016/j.jcou.2018.04.019
Marković D, Milovanović S, De Clerck K, Žižović I, Stojanović D, Radetić M. Development of material with strong antimicrobial activity by high pressure CO2 impregnation of polyamide nanofibers with thymol. in Journal of CO2 Utilization. 2018;26:19-27. doi:10.1016/j.jcou.2018.04.019 .
Marković, Darka, Milovanović, Stoja, De Clerck, Karen, Žižović, Irena, Stojanović, Dušica, Radetić, Maja, "Development of material with strong antimicrobial activity by high pressure CO2 impregnation of polyamide nanofibers with thymol" in Journal of CO2 Utilization, 26 (2018):19-27, https://doi.org/10.1016/j.jcou.2018.04.019 . .