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dc.creatorLović, Jelena
dc.creatorLađarević, Jelena
dc.creatorMijin, Dušan
dc.creatorJadranin, Milka
dc.creatorPetrović, Slobodan
dc.creatorAvramov-Ivić, Milka
dc.date.accessioned2021-03-10T13:57:18Z
dc.date.available2021-03-10T13:57:18Z
dc.date.issued2019
dc.identifier.issn0352-5139
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/4102
dc.description.abstractIn this study the electrochemical behavior of metformin (MET), oral antihyperglycaemic agent, was assayed at three different electrodes. The drug standard was investigated by cyclic voltammetry and square wave voltammetry via its electrooxidation at Au and glassy carbon electrode in 0.05 M NaHCO3. Under these conditions transformation of MET to corresponding N-carbonyl guanidine via oxime intermediate is suggested. The stability of MET was tested under directed stress conditions using IrOx electrode with sodium sulphate as an electrolyte and cyclic 4-amino-2-imino-1-methyl-1,2-dihydro-1,3,5-triazine appeared as the main end-product. The courses of the electrochemical processes at three electrodes were followed by UV spectroscopy and evaluated by total organic carbon analysis.en
dc.publisherSrpsko hemijsko društvo, Beograd
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172013/RS//
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172060/RS//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceJournal of the Serbian Chemical Society
dc.subjectcyclic voltammetryen
dc.subjectsquare wave voltammetryen
dc.subjectAu electrodeen
dc.subjectGC electrodeen
dc.subjectIrOX electrodeen
dc.subjecttotal organic carbon analysisen
dc.titleElectrochemical stability of metformin in NaHCO3 and Na2SO4 water solution at Au, GC and IrOx electrodesen
dc.typearticle
dc.rights.licenseBY-NC-ND
dc.citation.epage1327
dc.citation.issue11
dc.citation.other84(11): 1319-1327
dc.citation.rankM23
dc.citation.spage1319
dc.citation.volume84
dc.identifier.doi10.2298/JSC190731091L
dc.identifier.fulltexthttp://TechnoRep.tmf.bg.ac.rs/bitstream/id/1829/4099.pdf
dc.identifier.scopus2-s2.0-85076372324
dc.identifier.wos000500748300011
dc.type.versionpublishedVersion


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Приказ основних података о документу