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dc.creatorPetrović, Predrag
dc.creatorIvanović, Katarina
dc.creatorOctrue, Charly
dc.creatorTumara, Mica
dc.creatorJovanović, Aleksandra
dc.creatorVunduk, Jovana
dc.creatorNikšić, Miomir
dc.creatorPjanović, Rada
dc.creatorBugarski, Branko
dc.creatorKlaus, Anita
dc.date.accessioned2021-03-10T13:57:29Z
dc.date.available2021-03-10T13:57:29Z
dc.date.issued2019
dc.identifier.issn0367-598X
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/4105
dc.description.abstractChaga (Inonotus obliquus) is a parasitic fungus, which has been used in traditional medicine in Russia and other northern European countries in the treatment of cancer, gastrointestinal andliver diseases. It has been a subject of intensive researchrecently, confirming many of its health-beneficial effects. In order to obtain a product that would allow modified and prolonged release of the Chaga's active metabolites, hot water Chaga extract was immobilized using calcium - alginate. The extract, which was predominantly composed of carbohydrates (57 %), also contained a relatively high amount of antioxidants/phenolic compounds (130 mg gallic acid equivalents per g of dry extract) and exhibited pronounced radical scavenging activity. It showed significant antibacterial activity as well, inhibiting growth of tested bacterial strains at concentrations of 1.25-20 mg/mL. Entrapment efficiency was about 80 %, and the extract-alginate system showed pH-dependant extract release; there was negligible release at pH 1.75 (gastric pH), and the release gradually increased with the increase in pH, reaching similar to 43 % of immobilized extract at pH 8.5 after 90 min. Such a product could be used as a dietary supplement, adjuvant in therapy of gastrointestinal diseases or as a food additive.en
dc.publisherSavez hemijskih inženjera, Beograd
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46010/RS//
dc.rightsopenAccess
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/4.0/
dc.sourceHemijska industrija
dc.subjectmushroomsen
dc.subjectnatural producten
dc.subjectantioxidanten
dc.subjectantimicrobialen
dc.subjectencapsulationen
dc.titleImmobilization of Chaga extract in alginate beads for modified release: simplicity meets efficiencyen
dc.typearticle
dc.rights.licenseBY-NC-ND
dc.citation.epage335
dc.citation.issue5
dc.citation.other73(5): 325-335
dc.citation.rankM23
dc.citation.spage325
dc.citation.volume73
dc.identifier.doi10.2298/HEMIND190819028P
dc.identifier.fulltexthttp://TechnoRep.tmf.bg.ac.rs/bitstream/id/1833/4102.pdf
dc.identifier.rcubconv_5983
dc.identifier.scopus2-s2.0-85075240386
dc.identifier.wos000496945300005
dc.type.versionpublishedVersion


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