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dc.creatorNešović, Katarina
dc.creatorMišković-Stanković, Vesna
dc.date.accessioned2021-03-10T14:27:08Z
dc.date.available2021-03-10T14:27:08Z
dc.date.issued2020
dc.identifier.issn0861-9808
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/4568
dc.description.abstractSilver nanoparticles (AgNPs) have become an interesting alternative to antibiotics for potential applications in biomedicine, since nanocrystalline silver is proved to be highly efficient antimicrobial agent with a wide inhibiting spectrum against many types of microorganisms. AgNPs embedded in hydrogel matrices are attractive for biomedical applications due to the possibility for their controlled release resulting in enhanced antimicrobial activity. Thus, combination of AgNPs with biocompatible hydrogels, poly(vinyl alcohol) (PVA) and chitosan (CHI), provides potential for design of improved medical treatments and devices (antimicrobial wound dressings, soft tissue implants). Graphene (Gr) has exceptional mechanical properties and has therefore been applied as adequate reinforcing component for polymer-based composite materials. The synthesis of AgNPs is always subject to innovation and improvements, as it is desirable to minimize the use of chemical agents with the aim of improving the biocompatibility of the obtained material. With this in mind, a green alternative to traditional chemical synthesis methods would be the electrochemical reduction of silver ions, especially as this method provides the option of direct in situ synthesis of AgNPs inside the polymer matrix. In this paper, we provide an overview of the state of the art regarding graphene-reinforced polymer matrices with electrochemically synthesized silver nanoparticles for medical application. We show that the electrochemical method of AgNPs synthesis in PVA/CHI hydrogel matrices has emerged as an excellent method to obtain nanoparticles, and that the incorporation of graphene improved the hydrogels` mechanical properties and elasticity.en
dc.relationMinistry of Education, Science and Technological Development of the Republic of Serbia for funding.
dc.rightsrestrictedAccess
dc.sourceBulgarian Chemical Communications
dc.subjectChitosanen
dc.subjectElectrochemical synthesisen
dc.subjectGrapheneen
dc.subjectHydrogelen
dc.subjectSilver nanoparticlesen
dc.titleGraphene-based poly(vinyl alcohol)/chitosan hydrogels with electrochemically synthesized silver nanoparticles for medical applications – A reviewen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage14
dc.citation.other52: 5-14
dc.citation.spage5
dc.citation.volume52
dc.identifier.pmid
dc.identifier.rcubconv_6388
dc.identifier.scopus2-s2.0-85091662518
dc.type.versionpublishedVersion


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