Comparative investigation of selenium-enriched Pleurotus ostreatus and Ganoderma lucidum as natural sources of selenium supplementation
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2024
Authors
Milovanović, IvanChillon, Thilo Samson
Hackler, Julian
Schomburg, Lutz
Goessler, Walter
Lajin, Bassam
Article (Published version)
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Show full item recordAbstract
Selenium (Se) is an essential trace element for human health, but its nutritional supply is insufficient in large parts of the world. Mushrooms can be enriched in selenium and can serve as alternative and natural source of selenium supplementation. In the present study, two common mushroom species (Pleurotus ostreatus and Ganoderma lucidum), were enriched with two selenium compounds (selenite and selenate) to test their suitability as natural sources of selenium supplementation. Sharp differences in the the metabolic patterns of the fortified selenium were observed. Selenium was effectively metabolized in P. ostreatus but remained in inorganic form in G. lucidum. However, mushrooms extracts were effective in enhancing selenoprotein expression in cell lines. The present study highlights the importance of employing selenium speciation analysis with an element-selective technique to examine the metabolic products following mushroom fortification for nutritional purposes due to the differe...nt toxicological profile and bioavailability of different selenium biotransformation products.
Keywords:
Fortified nutrition / selenium speciation / Glutathione peroxidase / HPLC-ICP-MS/MS / SelenoproteinSource:
Food Chemistry, 2024, 437, 137842-Publisher:
- Elsevier Ltd.
Funding / projects:
- Ministry of Education, Science and Technological Development of the Republic of Serbia (Contract No. 451-03-693/2022-14)
- Ministry of Science, Technological Development and Innovation of the Republic of Serbia, institutional funding - 200287 (Innovation Center of the Faculty of Technology and Metallurgy) (RS-MESTD-inst-2020-200287)
Institution/Community
Inovacioni centarTY - JOUR AU - Milovanović, Ivan AU - Chillon, Thilo Samson AU - Hackler, Julian AU - Schomburg, Lutz AU - Goessler, Walter AU - Lajin, Bassam PY - 2024 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6910 AB - Selenium (Se) is an essential trace element for human health, but its nutritional supply is insufficient in large parts of the world. Mushrooms can be enriched in selenium and can serve as alternative and natural source of selenium supplementation. In the present study, two common mushroom species (Pleurotus ostreatus and Ganoderma lucidum), were enriched with two selenium compounds (selenite and selenate) to test their suitability as natural sources of selenium supplementation. Sharp differences in the the metabolic patterns of the fortified selenium were observed. Selenium was effectively metabolized in P. ostreatus but remained in inorganic form in G. lucidum. However, mushrooms extracts were effective in enhancing selenoprotein expression in cell lines. The present study highlights the importance of employing selenium speciation analysis with an element-selective technique to examine the metabolic products following mushroom fortification for nutritional purposes due to the different toxicological profile and bioavailability of different selenium biotransformation products. PB - Elsevier Ltd. T2 - Food Chemistry T1 - Comparative investigation of selenium-enriched Pleurotus ostreatus and Ganoderma lucidum as natural sources of selenium supplementation SP - 137842 VL - 437 DO - 10.1016/j.foodchem.2023.137842 ER -
@article{ author = "Milovanović, Ivan and Chillon, Thilo Samson and Hackler, Julian and Schomburg, Lutz and Goessler, Walter and Lajin, Bassam", year = "2024", abstract = "Selenium (Se) is an essential trace element for human health, but its nutritional supply is insufficient in large parts of the world. Mushrooms can be enriched in selenium and can serve as alternative and natural source of selenium supplementation. In the present study, two common mushroom species (Pleurotus ostreatus and Ganoderma lucidum), were enriched with two selenium compounds (selenite and selenate) to test their suitability as natural sources of selenium supplementation. Sharp differences in the the metabolic patterns of the fortified selenium were observed. Selenium was effectively metabolized in P. ostreatus but remained in inorganic form in G. lucidum. However, mushrooms extracts were effective in enhancing selenoprotein expression in cell lines. The present study highlights the importance of employing selenium speciation analysis with an element-selective technique to examine the metabolic products following mushroom fortification for nutritional purposes due to the different toxicological profile and bioavailability of different selenium biotransformation products.", publisher = "Elsevier Ltd.", journal = "Food Chemistry", title = "Comparative investigation of selenium-enriched Pleurotus ostreatus and Ganoderma lucidum as natural sources of selenium supplementation", pages = "137842", volume = "437", doi = "10.1016/j.foodchem.2023.137842" }
Milovanović, I., Chillon, T. S., Hackler, J., Schomburg, L., Goessler, W.,& Lajin, B.. (2024). Comparative investigation of selenium-enriched Pleurotus ostreatus and Ganoderma lucidum as natural sources of selenium supplementation. in Food Chemistry Elsevier Ltd.., 437, 137842. https://doi.org/10.1016/j.foodchem.2023.137842
Milovanović I, Chillon TS, Hackler J, Schomburg L, Goessler W, Lajin B. Comparative investigation of selenium-enriched Pleurotus ostreatus and Ganoderma lucidum as natural sources of selenium supplementation. in Food Chemistry. 2024;437:137842. doi:10.1016/j.foodchem.2023.137842 .
Milovanović, Ivan, Chillon, Thilo Samson, Hackler, Julian, Schomburg, Lutz, Goessler, Walter, Lajin, Bassam, "Comparative investigation of selenium-enriched Pleurotus ostreatus and Ganoderma lucidum as natural sources of selenium supplementation" in Food Chemistry, 437 (2024):137842, https://doi.org/10.1016/j.foodchem.2023.137842 . .