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dc.creatorMijin, Dušan
dc.creatorMilić, BD
dc.creatorMisić-Vuković, Milica
dc.date.accessioned2021-03-10T10:29:46Z
dc.date.available2021-03-10T10:29:46Z
dc.date.issued2006
dc.identifier.issn0376-4699
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/880
dc.description.abstractLipase from Candida rugosa has been used to Study the influence of 3-alkyl-2,4-pentanedione and N-alkyl cyanoacetamide Structure on the enzyme catalyzed reaction of pyridone ring formation in water at 40 degrees C. Starting with 1,3-diketones and cyanoacetamides and for comparison, the expected corresponding substituted 3-cyano-2-pyridones have been synthesized by chemical methods. Bulkier substituents lower the initial reaction rate of the enzyme catalyzed reactions and consequently the yield of the corresponding pyridones. N-alkyl cyanoacctamides are more reactive in comparison to the corresponding 3-alkyl-2,4-pentanediones with respect to the obtained yields of the corresponding substituted 3-cyano-2-pyridones..en
dc.publisherNatl Inst Science Communication, New Delhi
dc.rightsrestrictedAccess
dc.sourceIndian Journal of Chemistry - Section B Organic and Medicinal Chemistry
dc.subjectpyridoneen
dc.subjectlipaseen
dc.subjectdiketoneen
dc.subjectcyanoacetamideen
dc.titleSynthesis of substituted 3-cyano-2-pyridones: Part IV. Influence of 3-alkyl-2,4-pentanedione and N-alkyl cyanoacetamide structure on the enzyme catalyzed synthesis of substituted 3-cyano-2-pyridonesen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage1003
dc.citation.issue4
dc.citation.other45(4): 993-1003
dc.citation.rankM23
dc.citation.spage993
dc.citation.volume45
dc.identifier.pmid
dc.identifier.rcubhttps://hdl.handle.net/21.15107/rcub_technorep_880
dc.identifier.scopus2-s2.0-33744917251
dc.identifier.wos000236913600010
dc.type.versionpublishedVersion


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Приказ основних података о документу