Investigation of Ca-alginate hydrogel rheological behaviour in conjunction with immobilized yeast cell growth dynamics
Само за регистроване кориснике
2007
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The rheological model is developed to elucidate the mechanism of Ca-alginate microbead deformation in the course of cell growth within. It is a complex process influenced by relaxation of the expanded polymer network inside a bead, and forces generated by cell growth inside the bead and interactions between solvent, network parts and cells as well. The resulting effects are measured experimentally by estimating isotropic volumetric deformations of beads with yeast cells as function of time and cell concentration per bead. The mathematical model of the process is developed based on a modified general Zener model with fractional derivatives. It is particularly suitable for incorporating effects of different nature also during different stages of such complex process development. The results of theoretical analyses using the model developed and comparison with experimental values obtained, indicate a high impact of partial decomposition, i.e. plastic response of polymer network inside a b...ead due to cell growth, on bead deformation. For comparison, corresponding deformation measurements and modelling were performed on the same network system exposed to swelling in the solvent, but without the cells. In this case elastic forces are dominant, indicating different mechanism of relaxation without the influence of cells, in agreement with previous conclusions.
Кључне речи:
microbead / yeast / alginates / cell growth / gel deformation mechanismИзвор:
Journal of Microencapsulation, 2007, 24, 5, 420-429Издавач:
- Taylor & Francis Ltd, Abingdon
DOI: 10.1080/02652040701362843
ISSN: 0265-2048
PubMed: 17578732
WoS: 000247967000003
Scopus: 2-s2.0-34347217518
Институција/група
Tehnološko-metalurški fakultetTY - JOUR AU - Pajić-Lijaković, Ivana AU - Plavšić, Milenko B. AU - Nedović, Viktor AU - Bugarski, Branko PY - 2007 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1159 AB - The rheological model is developed to elucidate the mechanism of Ca-alginate microbead deformation in the course of cell growth within. It is a complex process influenced by relaxation of the expanded polymer network inside a bead, and forces generated by cell growth inside the bead and interactions between solvent, network parts and cells as well. The resulting effects are measured experimentally by estimating isotropic volumetric deformations of beads with yeast cells as function of time and cell concentration per bead. The mathematical model of the process is developed based on a modified general Zener model with fractional derivatives. It is particularly suitable for incorporating effects of different nature also during different stages of such complex process development. The results of theoretical analyses using the model developed and comparison with experimental values obtained, indicate a high impact of partial decomposition, i.e. plastic response of polymer network inside a bead due to cell growth, on bead deformation. For comparison, corresponding deformation measurements and modelling were performed on the same network system exposed to swelling in the solvent, but without the cells. In this case elastic forces are dominant, indicating different mechanism of relaxation without the influence of cells, in agreement with previous conclusions. PB - Taylor & Francis Ltd, Abingdon T2 - Journal of Microencapsulation T1 - Investigation of Ca-alginate hydrogel rheological behaviour in conjunction with immobilized yeast cell growth dynamics EP - 429 IS - 5 SP - 420 VL - 24 DO - 10.1080/02652040701362843 ER -
@article{ author = "Pajić-Lijaković, Ivana and Plavšić, Milenko B. and Nedović, Viktor and Bugarski, Branko", year = "2007", abstract = "The rheological model is developed to elucidate the mechanism of Ca-alginate microbead deformation in the course of cell growth within. It is a complex process influenced by relaxation of the expanded polymer network inside a bead, and forces generated by cell growth inside the bead and interactions between solvent, network parts and cells as well. The resulting effects are measured experimentally by estimating isotropic volumetric deformations of beads with yeast cells as function of time and cell concentration per bead. The mathematical model of the process is developed based on a modified general Zener model with fractional derivatives. It is particularly suitable for incorporating effects of different nature also during different stages of such complex process development. The results of theoretical analyses using the model developed and comparison with experimental values obtained, indicate a high impact of partial decomposition, i.e. plastic response of polymer network inside a bead due to cell growth, on bead deformation. For comparison, corresponding deformation measurements and modelling were performed on the same network system exposed to swelling in the solvent, but without the cells. In this case elastic forces are dominant, indicating different mechanism of relaxation without the influence of cells, in agreement with previous conclusions.", publisher = "Taylor & Francis Ltd, Abingdon", journal = "Journal of Microencapsulation", title = "Investigation of Ca-alginate hydrogel rheological behaviour in conjunction with immobilized yeast cell growth dynamics", pages = "429-420", number = "5", volume = "24", doi = "10.1080/02652040701362843" }
Pajić-Lijaković, I., Plavšić, M. B., Nedović, V.,& Bugarski, B.. (2007). Investigation of Ca-alginate hydrogel rheological behaviour in conjunction with immobilized yeast cell growth dynamics. in Journal of Microencapsulation Taylor & Francis Ltd, Abingdon., 24(5), 420-429. https://doi.org/10.1080/02652040701362843
Pajić-Lijaković I, Plavšić MB, Nedović V, Bugarski B. Investigation of Ca-alginate hydrogel rheological behaviour in conjunction with immobilized yeast cell growth dynamics. in Journal of Microencapsulation. 2007;24(5):420-429. doi:10.1080/02652040701362843 .
Pajić-Lijaković, Ivana, Plavšić, Milenko B., Nedović, Viktor, Bugarski, Branko, "Investigation of Ca-alginate hydrogel rheological behaviour in conjunction with immobilized yeast cell growth dynamics" in Journal of Microencapsulation, 24, no. 5 (2007):420-429, https://doi.org/10.1080/02652040701362843 . .