Network Theory of Living Cell Clusters and Rheological Applications at Nano-Level
Abstract
The system of living cells closed in a polymer matrix and self-organized into clusters is considered, extending free volume concept developed for complex system interactions quantification in statistical mechanics of jammed state of matter. Possibility of extension of Edwards concept of compactivity and angorisity developed for hard irregular grains with friction to living cell systems, is considered. Existences of scaling laws for cell colony grow, related to their self assembling and response to polymer hydrogel micro-environment constrains, is analyzed as function of rate of cluster density increase. Based on the theory proposed are developed relations, connecting cluster properties that are difficult to measure, to data from standard cell cultivation experiments. The model also provides possibilities of incorporation data on single cell behavior, available from modern nano- rheology measurements, into cluster
Source:
Acta Physica Polonica A, 2011, 120, 2, 266-271Publisher:
- Polish Acad Sciences Inst Physics, Warsaw
Funding / projects:
- Novel encapsulation and enzyme technologies for designing of new biocatalysts and biologically active compounds targeting enhancement of food quality, safety and competitiveness (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-46010)
DOI: 10.12693/APhysPolA.120.266
ISSN: 0587-4246
WoS: 000291836900014
Scopus: 2-s2.0-79960143183
Institution/Community
Tehnološko-metalurški fakultetTY - JOUR AU - Plavšić, Milenko B. AU - Pajić-Lijaković, Ivana AU - Plavšić, Milenko B. AU - Bugarski, Branko PY - 2011 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1955 AB - The system of living cells closed in a polymer matrix and self-organized into clusters is considered, extending free volume concept developed for complex system interactions quantification in statistical mechanics of jammed state of matter. Possibility of extension of Edwards concept of compactivity and angorisity developed for hard irregular grains with friction to living cell systems, is considered. Existences of scaling laws for cell colony grow, related to their self assembling and response to polymer hydrogel micro-environment constrains, is analyzed as function of rate of cluster density increase. Based on the theory proposed are developed relations, connecting cluster properties that are difficult to measure, to data from standard cell cultivation experiments. The model also provides possibilities of incorporation data on single cell behavior, available from modern nano- rheology measurements, into cluster PB - Polish Acad Sciences Inst Physics, Warsaw T2 - Acta Physica Polonica A T1 - Network Theory of Living Cell Clusters and Rheological Applications at Nano-Level EP - 271 IS - 2 SP - 266 VL - 120 DO - 10.12693/APhysPolA.120.266 ER -
@article{ author = "Plavšić, Milenko B. and Pajić-Lijaković, Ivana and Plavšić, Milenko B. and Bugarski, Branko", year = "2011", abstract = "The system of living cells closed in a polymer matrix and self-organized into clusters is considered, extending free volume concept developed for complex system interactions quantification in statistical mechanics of jammed state of matter. Possibility of extension of Edwards concept of compactivity and angorisity developed for hard irregular grains with friction to living cell systems, is considered. Existences of scaling laws for cell colony grow, related to their self assembling and response to polymer hydrogel micro-environment constrains, is analyzed as function of rate of cluster density increase. Based on the theory proposed are developed relations, connecting cluster properties that are difficult to measure, to data from standard cell cultivation experiments. The model also provides possibilities of incorporation data on single cell behavior, available from modern nano- rheology measurements, into cluster", publisher = "Polish Acad Sciences Inst Physics, Warsaw", journal = "Acta Physica Polonica A", title = "Network Theory of Living Cell Clusters and Rheological Applications at Nano-Level", pages = "271-266", number = "2", volume = "120", doi = "10.12693/APhysPolA.120.266" }
Plavšić, M. B., Pajić-Lijaković, I., Plavšić, M. B.,& Bugarski, B.. (2011). Network Theory of Living Cell Clusters and Rheological Applications at Nano-Level. in Acta Physica Polonica A Polish Acad Sciences Inst Physics, Warsaw., 120(2), 266-271. https://doi.org/10.12693/APhysPolA.120.266
Plavšić MB, Pajić-Lijaković I, Plavšić MB, Bugarski B. Network Theory of Living Cell Clusters and Rheological Applications at Nano-Level. in Acta Physica Polonica A. 2011;120(2):266-271. doi:10.12693/APhysPolA.120.266 .
Plavšić, Milenko B., Pajić-Lijaković, Ivana, Plavšić, Milenko B., Bugarski, Branko, "Network Theory of Living Cell Clusters and Rheological Applications at Nano-Level" in Acta Physica Polonica A, 120, no. 2 (2011):266-271, https://doi.org/10.12693/APhysPolA.120.266 . .