Antibacterial activity of copper-containing clinoptilolite/PVC composites toward clinical isolate of Acinetobacter baumannii
Abstract
The multidrug-resistant bacteria Acinetobacter baumannii cause serious hospital infections. Commercial poly(vinyl chloride) (PVC) used for endotracheal tubes was modified in order to obtain a composite with an antibacterial effect towards a clinical isolate of A. baumannii ST145. The composites were prepared by addition of different amounts of copper-containing zeolite tuff (CuZ) and by successive impregnation with D-tyrosine (D-Tyr) solution. The composites that were obtained by addition of CuZ (CuZ PVC) only did not exhibit an antibacterial effect. The impregnation of the CuZ PVC by D-Tyr resulted in an antibacterial effect which was explained by a synergistic effect of CuZ and D-Tyr. Rheological tests confirmed that the modification of PVC by CuZ does not affect its processability and reformability.
Keywords:
natural zeolite / multidrug resistance / polymers / poly(vinyl chloride) / amino acidsSource:
Journal of the Serbian Chemical Society, 2015, 80, 6, 819-826Publisher:
- Srpsko hemijsko društvo, Beograd
Funding / projects:
- Oxide-based environmentally-friendly porous materials for genotoxic substances removal (RS-MESTD-Basic Research (BR or ON)-172018)
- Ministry of Science, Education and Sports of the Republic of CroatiaMinistry of Science, Education and Sports, Republic of Croatia [1191155-1203]
DOI: 10.2298/JSC141225017M
ISSN: 0352-5139
WoS: 000357758900010
Scopus: 2-s2.0-84938921768
Collections
Institution/Community
Tehnološko-metalurški fakultetTY - JOUR AU - Dikić, Jelena AU - Hrenović, Jasna AU - Goić-Barisić, Ivana AU - Tomić, Miloš D. AU - Rajić, Nevenka PY - 2015 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3122 AB - The multidrug-resistant bacteria Acinetobacter baumannii cause serious hospital infections. Commercial poly(vinyl chloride) (PVC) used for endotracheal tubes was modified in order to obtain a composite with an antibacterial effect towards a clinical isolate of A. baumannii ST145. The composites were prepared by addition of different amounts of copper-containing zeolite tuff (CuZ) and by successive impregnation with D-tyrosine (D-Tyr) solution. The composites that were obtained by addition of CuZ (CuZ PVC) only did not exhibit an antibacterial effect. The impregnation of the CuZ PVC by D-Tyr resulted in an antibacterial effect which was explained by a synergistic effect of CuZ and D-Tyr. Rheological tests confirmed that the modification of PVC by CuZ does not affect its processability and reformability. PB - Srpsko hemijsko društvo, Beograd T2 - Journal of the Serbian Chemical Society T1 - Antibacterial activity of copper-containing clinoptilolite/PVC composites toward clinical isolate of Acinetobacter baumannii EP - 826 IS - 6 SP - 819 VL - 80 DO - 10.2298/JSC141225017M ER -
@article{ author = "Dikić, Jelena and Hrenović, Jasna and Goić-Barisić, Ivana and Tomić, Miloš D. and Rajić, Nevenka", year = "2015", abstract = "The multidrug-resistant bacteria Acinetobacter baumannii cause serious hospital infections. Commercial poly(vinyl chloride) (PVC) used for endotracheal tubes was modified in order to obtain a composite with an antibacterial effect towards a clinical isolate of A. baumannii ST145. The composites were prepared by addition of different amounts of copper-containing zeolite tuff (CuZ) and by successive impregnation with D-tyrosine (D-Tyr) solution. The composites that were obtained by addition of CuZ (CuZ PVC) only did not exhibit an antibacterial effect. The impregnation of the CuZ PVC by D-Tyr resulted in an antibacterial effect which was explained by a synergistic effect of CuZ and D-Tyr. Rheological tests confirmed that the modification of PVC by CuZ does not affect its processability and reformability.", publisher = "Srpsko hemijsko društvo, Beograd", journal = "Journal of the Serbian Chemical Society", title = "Antibacterial activity of copper-containing clinoptilolite/PVC composites toward clinical isolate of Acinetobacter baumannii", pages = "826-819", number = "6", volume = "80", doi = "10.2298/JSC141225017M" }
Dikić, J., Hrenović, J., Goić-Barisić, I., Tomić, M. D.,& Rajić, N.. (2015). Antibacterial activity of copper-containing clinoptilolite/PVC composites toward clinical isolate of Acinetobacter baumannii. in Journal of the Serbian Chemical Society Srpsko hemijsko društvo, Beograd., 80(6), 819-826. https://doi.org/10.2298/JSC141225017M
Dikić J, Hrenović J, Goić-Barisić I, Tomić MD, Rajić N. Antibacterial activity of copper-containing clinoptilolite/PVC composites toward clinical isolate of Acinetobacter baumannii. in Journal of the Serbian Chemical Society. 2015;80(6):819-826. doi:10.2298/JSC141225017M .
Dikić, Jelena, Hrenović, Jasna, Goić-Barisić, Ivana, Tomić, Miloš D., Rajić, Nevenka, "Antibacterial activity of copper-containing clinoptilolite/PVC composites toward clinical isolate of Acinetobacter baumannii" in Journal of the Serbian Chemical Society, 80, no. 6 (2015):819-826, https://doi.org/10.2298/JSC141225017M . .