Optimization of supercritical CO2 extraction of fenugreek seed (Trigonella foenum-graecum L.) and calculating of extracts solubility
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2016
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Supercritical CO2 (SC-CO2) extraction of fenugreek seeds (Trigonella foenum-graecum L, Fabaceae) was analyzed using different pressure and temperature (16.6-33.4 MPa and, 30-50 degrees C), which corresponded to SC-CO2 density between 779 and 957 kg/m(3). The yield of extract as well as its composition were determined and analyzed for different solvent consumption defined as mass of used CO2 for extraction per mass of dry fenugreek seeds. A central composite design (CCD) combined with response surface methodology (RSM) was used to study the best extraction conditions which determined that 27.0 MPa, 42.6 degrees C, and 24.6 gCO(2)/g(dm), were the optimal conditions for isolation of total extract. The calculated yield of extract at these conditions defined by SC-CO2 density of 890 kg/m3 could be 2.57% based on fenugreek seed. Moreover, the best extraction conditions for obtaining extract which contains the maximal amount of sterols, or maximal amount of vitamin E or vitamin D were also an...alyzed. These RSM optimizations showed that at slightly lower pressure (22.8-24.8 MPa), temperature (39.9-42.0 degrees C) and consumption of SC-CO2 (19.0-19.7 gCO(2)/g(dm)) is followed by smaller amount of isolated extract but with maximum content of sterols (16.28%), or vitamin E or vitamin D (1.44% and 0.71%, respectively) at these conditions. Calculation of molar solubility of total extract, and apparent solubility of sterols, vitamin E and D in SC-CO2 was performed at different pressure and temperature. They were correlated to density of SC-CO2, temperature at which extractions were performed and Hildebrand solubility parameter of solvent and solubility parameter of compounds which are the main constituents of extract. These calculations also show that the highest molar solubility of total extract and apparent molar solubility of its constituents could be obtained using optimal density of SC-CO2 (830-890 kg/m(3)) defined by corresponding values of temperature and pressure (310-320 K and 20-25 MPa).
Ključne reči:
Supercritical extraction / Fenugreek / Optimization / RSM / SolubilityIzvor:
Journal of Supercritical Fluids, 2016, 117, 297-307Izdavač:
- Elsevier Science Bv, Amsterdam
Finansiranje / projekti:
DOI: 10.1016/j.supflu.2016.07.010
ISSN: 0896-8446
WoS: 000382410800032
Scopus: 2-s2.0-84989930955
Institucija/grupa
Tehnološko-metalurški fakultetTY - JOUR AU - Bogdanović, Aleksandra AU - Tadić, Vanja AU - Ristić, Mihailo S. AU - Petrović, Slobodan AU - Skala, Dejan PY - 2016 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3344 AB - Supercritical CO2 (SC-CO2) extraction of fenugreek seeds (Trigonella foenum-graecum L, Fabaceae) was analyzed using different pressure and temperature (16.6-33.4 MPa and, 30-50 degrees C), which corresponded to SC-CO2 density between 779 and 957 kg/m(3). The yield of extract as well as its composition were determined and analyzed for different solvent consumption defined as mass of used CO2 for extraction per mass of dry fenugreek seeds. A central composite design (CCD) combined with response surface methodology (RSM) was used to study the best extraction conditions which determined that 27.0 MPa, 42.6 degrees C, and 24.6 gCO(2)/g(dm), were the optimal conditions for isolation of total extract. The calculated yield of extract at these conditions defined by SC-CO2 density of 890 kg/m3 could be 2.57% based on fenugreek seed. Moreover, the best extraction conditions for obtaining extract which contains the maximal amount of sterols, or maximal amount of vitamin E or vitamin D were also analyzed. These RSM optimizations showed that at slightly lower pressure (22.8-24.8 MPa), temperature (39.9-42.0 degrees C) and consumption of SC-CO2 (19.0-19.7 gCO(2)/g(dm)) is followed by smaller amount of isolated extract but with maximum content of sterols (16.28%), or vitamin E or vitamin D (1.44% and 0.71%, respectively) at these conditions. Calculation of molar solubility of total extract, and apparent solubility of sterols, vitamin E and D in SC-CO2 was performed at different pressure and temperature. They were correlated to density of SC-CO2, temperature at which extractions were performed and Hildebrand solubility parameter of solvent and solubility parameter of compounds which are the main constituents of extract. These calculations also show that the highest molar solubility of total extract and apparent molar solubility of its constituents could be obtained using optimal density of SC-CO2 (830-890 kg/m(3)) defined by corresponding values of temperature and pressure (310-320 K and 20-25 MPa). PB - Elsevier Science Bv, Amsterdam T2 - Journal of Supercritical Fluids T1 - Optimization of supercritical CO2 extraction of fenugreek seed (Trigonella foenum-graecum L.) and calculating of extracts solubility EP - 307 SP - 297 VL - 117 DO - 10.1016/j.supflu.2016.07.010 ER -
@article{ author = "Bogdanović, Aleksandra and Tadić, Vanja and Ristić, Mihailo S. and Petrović, Slobodan and Skala, Dejan", year = "2016", abstract = "Supercritical CO2 (SC-CO2) extraction of fenugreek seeds (Trigonella foenum-graecum L, Fabaceae) was analyzed using different pressure and temperature (16.6-33.4 MPa and, 30-50 degrees C), which corresponded to SC-CO2 density between 779 and 957 kg/m(3). The yield of extract as well as its composition were determined and analyzed for different solvent consumption defined as mass of used CO2 for extraction per mass of dry fenugreek seeds. A central composite design (CCD) combined with response surface methodology (RSM) was used to study the best extraction conditions which determined that 27.0 MPa, 42.6 degrees C, and 24.6 gCO(2)/g(dm), were the optimal conditions for isolation of total extract. The calculated yield of extract at these conditions defined by SC-CO2 density of 890 kg/m3 could be 2.57% based on fenugreek seed. Moreover, the best extraction conditions for obtaining extract which contains the maximal amount of sterols, or maximal amount of vitamin E or vitamin D were also analyzed. These RSM optimizations showed that at slightly lower pressure (22.8-24.8 MPa), temperature (39.9-42.0 degrees C) and consumption of SC-CO2 (19.0-19.7 gCO(2)/g(dm)) is followed by smaller amount of isolated extract but with maximum content of sterols (16.28%), or vitamin E or vitamin D (1.44% and 0.71%, respectively) at these conditions. Calculation of molar solubility of total extract, and apparent solubility of sterols, vitamin E and D in SC-CO2 was performed at different pressure and temperature. They were correlated to density of SC-CO2, temperature at which extractions were performed and Hildebrand solubility parameter of solvent and solubility parameter of compounds which are the main constituents of extract. These calculations also show that the highest molar solubility of total extract and apparent molar solubility of its constituents could be obtained using optimal density of SC-CO2 (830-890 kg/m(3)) defined by corresponding values of temperature and pressure (310-320 K and 20-25 MPa).", publisher = "Elsevier Science Bv, Amsterdam", journal = "Journal of Supercritical Fluids", title = "Optimization of supercritical CO2 extraction of fenugreek seed (Trigonella foenum-graecum L.) and calculating of extracts solubility", pages = "307-297", volume = "117", doi = "10.1016/j.supflu.2016.07.010" }
Bogdanović, A., Tadić, V., Ristić, M. S., Petrović, S.,& Skala, D.. (2016). Optimization of supercritical CO2 extraction of fenugreek seed (Trigonella foenum-graecum L.) and calculating of extracts solubility. in Journal of Supercritical Fluids Elsevier Science Bv, Amsterdam., 117, 297-307. https://doi.org/10.1016/j.supflu.2016.07.010
Bogdanović A, Tadić V, Ristić MS, Petrović S, Skala D. Optimization of supercritical CO2 extraction of fenugreek seed (Trigonella foenum-graecum L.) and calculating of extracts solubility. in Journal of Supercritical Fluids. 2016;117:297-307. doi:10.1016/j.supflu.2016.07.010 .
Bogdanović, Aleksandra, Tadić, Vanja, Ristić, Mihailo S., Petrović, Slobodan, Skala, Dejan, "Optimization of supercritical CO2 extraction of fenugreek seed (Trigonella foenum-graecum L.) and calculating of extracts solubility" in Journal of Supercritical Fluids, 117 (2016):297-307, https://doi.org/10.1016/j.supflu.2016.07.010 . .