Graphene Based Composite Hydrogel for Biomedical Applications
Abstract
In this work, composite hydrogel consisting of poly(vinyl alcohol), graphene and silver nanoparticles, (Ag/PVA/Gr), was prepared by the immobilization of silver nanoparticles (AgNPs) in PVA/Gr hydrogel matrix in two steps. The first step was cross linking of the PVA/Gr colloid solution by the freezing/thawing method, while in the second step, in situ electrochemical method was used to incorporate AgNPs inside the PVA/Gr hydrogel matrix. We used UV-vis spectroscopy, cyclic voltammetry, Raman spectroscopy, DSC analysis, as well as test of cytotoxicity and antibacterial activity, to characterize obtained Ag/PVA/Gr hydrogel. It was shown that graphene- based composite hydrogel with incorporated AgNPs is non toxic biomaterial with antibacterial activity, with a potential for use in biomedical purposes.
Keywords:
hydrogels / silver nanoparticles / poly(vinyl alcohol) / graphene / nanocomposites / electrochemical synthesisSource:
Croatica Chemica Acta, 2017, 90, 2, 207-213Publisher:
- Croatian Chemical Soc, Zagreb
Funding / projects:
- Basic Science Research Program through National Research Foundation of Korea (NRF) - Ministry of Education, Science and Technology [2016R1A2B4016034]
- Synthesis, processing and applications of nanostructured multifunctional materials with defined properties (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45019)
DOI: 10.5562/cca3133
ISSN: 0011-1643
WoS: 000416047000013
Scopus: 2-s2.0-85038817149
Collections
Institution/Community
Tehnološko-metalurški fakultetTY - JOUR AU - Nešović, Katarina AU - Abudabbus, Mohamed M. AU - Rhee, Kyong Yop AU - Mišković-Stanković, Vesna PY - 2017 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3620 AB - In this work, composite hydrogel consisting of poly(vinyl alcohol), graphene and silver nanoparticles, (Ag/PVA/Gr), was prepared by the immobilization of silver nanoparticles (AgNPs) in PVA/Gr hydrogel matrix in two steps. The first step was cross linking of the PVA/Gr colloid solution by the freezing/thawing method, while in the second step, in situ electrochemical method was used to incorporate AgNPs inside the PVA/Gr hydrogel matrix. We used UV-vis spectroscopy, cyclic voltammetry, Raman spectroscopy, DSC analysis, as well as test of cytotoxicity and antibacterial activity, to characterize obtained Ag/PVA/Gr hydrogel. It was shown that graphene- based composite hydrogel with incorporated AgNPs is non toxic biomaterial with antibacterial activity, with a potential for use in biomedical purposes. PB - Croatian Chemical Soc, Zagreb T2 - Croatica Chemica Acta T1 - Graphene Based Composite Hydrogel for Biomedical Applications EP - 213 IS - 2 SP - 207 VL - 90 DO - 10.5562/cca3133 ER -
@article{ author = "Nešović, Katarina and Abudabbus, Mohamed M. and Rhee, Kyong Yop and Mišković-Stanković, Vesna", year = "2017", abstract = "In this work, composite hydrogel consisting of poly(vinyl alcohol), graphene and silver nanoparticles, (Ag/PVA/Gr), was prepared by the immobilization of silver nanoparticles (AgNPs) in PVA/Gr hydrogel matrix in two steps. The first step was cross linking of the PVA/Gr colloid solution by the freezing/thawing method, while in the second step, in situ electrochemical method was used to incorporate AgNPs inside the PVA/Gr hydrogel matrix. We used UV-vis spectroscopy, cyclic voltammetry, Raman spectroscopy, DSC analysis, as well as test of cytotoxicity and antibacterial activity, to characterize obtained Ag/PVA/Gr hydrogel. It was shown that graphene- based composite hydrogel with incorporated AgNPs is non toxic biomaterial with antibacterial activity, with a potential for use in biomedical purposes.", publisher = "Croatian Chemical Soc, Zagreb", journal = "Croatica Chemica Acta", title = "Graphene Based Composite Hydrogel for Biomedical Applications", pages = "213-207", number = "2", volume = "90", doi = "10.5562/cca3133" }
Nešović, K., Abudabbus, M. M., Rhee, K. Y.,& Mišković-Stanković, V.. (2017). Graphene Based Composite Hydrogel for Biomedical Applications. in Croatica Chemica Acta Croatian Chemical Soc, Zagreb., 90(2), 207-213. https://doi.org/10.5562/cca3133
Nešović K, Abudabbus MM, Rhee KY, Mišković-Stanković V. Graphene Based Composite Hydrogel for Biomedical Applications. in Croatica Chemica Acta. 2017;90(2):207-213. doi:10.5562/cca3133 .
Nešović, Katarina, Abudabbus, Mohamed M., Rhee, Kyong Yop, Mišković-Stanković, Vesna, "Graphene Based Composite Hydrogel for Biomedical Applications" in Croatica Chemica Acta, 90, no. 2 (2017):207-213, https://doi.org/10.5562/cca3133 . .