Enzymatic Syntheses of Esters - Green Chemistry for Valuable Food, Fuel and Fine Chemicals
Нема приказа
Аутори
Bezbradica, DejanĆorović, Marija
Jakovetić Tanasković, Sonja
Luković, Nevena
Simović, Milica
Milivojević, Ana
Knežević-Jugović, Zorica
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The esterification is well-established type of reaction in organic synthesis used for manufacturing various valuable esters used prevalently as ingredients of food, skincare products, pharmaceuticals and fuels. In recent decades biocatalytic synthetic routes based on using enzymes as catalysts have received a lot of attention in scientific researches and industry. Main advantages of enzymatic esterifications are high selectivity (regioselectivity and enantioselectivity), performing reaction at milder conditions (moderate temperature and atmospheric pressure) and the fact that enzymatically synthesized product gain label of natural product, which increases its market appeal. The purpose of this review is to point out the most important advances in lipase-catalyzed ester synthesis in non-conventional reaction media, with special focus on several most important types of ester. This part of review starts with outcomes in synthesis of aroma esters, usually obtained using monofunctional alip...hatic alcohols and acids, which have been investigated for decades and industrial processes are already established. However, later sections are dedicated to enzymatic esterification of more complex molecules (carbohydrates, vitamin C, flavonoids) having more than one functional groups, which are subject of numerous studies in recent times because in these reactions regioselectivity of biocatalysts can be fully explored and processes are still subject of optimization, especially with respect to selection of reaction media and media engineering.
Кључне речи:
Aroma / biodiesel / carbohydrate / ester / flavonoid / immobilization / ionic liquid / lipaseИзвор:
Current Organic Chemistry, 2017, 21, 2, 104-138Издавач:
- Bentham Science Publ Ltd, Sharjah
Финансирање / пројекти:
- Развој нових инкапсулационих и ензимских технологија за производњу биокатализатора и биолошки активних компонената хране у циљу повећања њене конкурентности, квалитета и безбедности (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-46010)
DOI: 10.2174/1385272821666161108123326
ISSN: 1385-2728
WoS: 000390350300003
Scopus: 2-s2.0-85031090516
Колекције
Институција/група
Tehnološko-metalurški fakultetTY - JOUR AU - Bezbradica, Dejan AU - Ćorović, Marija AU - Jakovetić Tanasković, Sonja AU - Luković, Nevena AU - Simović, Milica AU - Milivojević, Ana AU - Knežević-Jugović, Zorica PY - 2017 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3664 AB - The esterification is well-established type of reaction in organic synthesis used for manufacturing various valuable esters used prevalently as ingredients of food, skincare products, pharmaceuticals and fuels. In recent decades biocatalytic synthetic routes based on using enzymes as catalysts have received a lot of attention in scientific researches and industry. Main advantages of enzymatic esterifications are high selectivity (regioselectivity and enantioselectivity), performing reaction at milder conditions (moderate temperature and atmospheric pressure) and the fact that enzymatically synthesized product gain label of natural product, which increases its market appeal. The purpose of this review is to point out the most important advances in lipase-catalyzed ester synthesis in non-conventional reaction media, with special focus on several most important types of ester. This part of review starts with outcomes in synthesis of aroma esters, usually obtained using monofunctional aliphatic alcohols and acids, which have been investigated for decades and industrial processes are already established. However, later sections are dedicated to enzymatic esterification of more complex molecules (carbohydrates, vitamin C, flavonoids) having more than one functional groups, which are subject of numerous studies in recent times because in these reactions regioselectivity of biocatalysts can be fully explored and processes are still subject of optimization, especially with respect to selection of reaction media and media engineering. PB - Bentham Science Publ Ltd, Sharjah T2 - Current Organic Chemistry T1 - Enzymatic Syntheses of Esters - Green Chemistry for Valuable Food, Fuel and Fine Chemicals EP - 138 IS - 2 SP - 104 VL - 21 DO - 10.2174/1385272821666161108123326 ER -
@article{ author = "Bezbradica, Dejan and Ćorović, Marija and Jakovetić Tanasković, Sonja and Luković, Nevena and Simović, Milica and Milivojević, Ana and Knežević-Jugović, Zorica", year = "2017", abstract = "The esterification is well-established type of reaction in organic synthesis used for manufacturing various valuable esters used prevalently as ingredients of food, skincare products, pharmaceuticals and fuels. In recent decades biocatalytic synthetic routes based on using enzymes as catalysts have received a lot of attention in scientific researches and industry. Main advantages of enzymatic esterifications are high selectivity (regioselectivity and enantioselectivity), performing reaction at milder conditions (moderate temperature and atmospheric pressure) and the fact that enzymatically synthesized product gain label of natural product, which increases its market appeal. The purpose of this review is to point out the most important advances in lipase-catalyzed ester synthesis in non-conventional reaction media, with special focus on several most important types of ester. This part of review starts with outcomes in synthesis of aroma esters, usually obtained using monofunctional aliphatic alcohols and acids, which have been investigated for decades and industrial processes are already established. However, later sections are dedicated to enzymatic esterification of more complex molecules (carbohydrates, vitamin C, flavonoids) having more than one functional groups, which are subject of numerous studies in recent times because in these reactions regioselectivity of biocatalysts can be fully explored and processes are still subject of optimization, especially with respect to selection of reaction media and media engineering.", publisher = "Bentham Science Publ Ltd, Sharjah", journal = "Current Organic Chemistry", title = "Enzymatic Syntheses of Esters - Green Chemistry for Valuable Food, Fuel and Fine Chemicals", pages = "138-104", number = "2", volume = "21", doi = "10.2174/1385272821666161108123326" }
Bezbradica, D., Ćorović, M., Jakovetić Tanasković, S., Luković, N., Simović, M., Milivojević, A.,& Knežević-Jugović, Z.. (2017). Enzymatic Syntheses of Esters - Green Chemistry for Valuable Food, Fuel and Fine Chemicals. in Current Organic Chemistry Bentham Science Publ Ltd, Sharjah., 21(2), 104-138. https://doi.org/10.2174/1385272821666161108123326
Bezbradica D, Ćorović M, Jakovetić Tanasković S, Luković N, Simović M, Milivojević A, Knežević-Jugović Z. Enzymatic Syntheses of Esters - Green Chemistry for Valuable Food, Fuel and Fine Chemicals. in Current Organic Chemistry. 2017;21(2):104-138. doi:10.2174/1385272821666161108123326 .
Bezbradica, Dejan, Ćorović, Marija, Jakovetić Tanasković, Sonja, Luković, Nevena, Simović, Milica, Milivojević, Ana, Knežević-Jugović, Zorica, "Enzymatic Syntheses of Esters - Green Chemistry for Valuable Food, Fuel and Fine Chemicals" in Current Organic Chemistry, 21, no. 2 (2017):104-138, https://doi.org/10.2174/1385272821666161108123326 . .