Degradation of azithromycin using Ti/RuO2 anode as catalyst followed by DPV, HPLC-UV and MS analysis
Само за регистроване кориснике
2017
Аутори
Radosavljević, Kristina D.Lović, Jelena
Mijin, Dušan
Petrović, Slobodan
Jadranin, Milka
Mladenović, Aleksandar R.
Avramov-Ivić, Milka
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The electrodegradation of azithromycin was studied by its indirect oxidation using dimensionally stable Ti/RuO2 anode as catalyst in the electrolyte containing methanol, 0.05 M NaHCO3, sodium chloride and deionized water. The optimal conditions for galvanostatic electrodegradation for the azithromycin concentration of 0.472 mg cm(-3) were found to be NaCl concentration of 7 mg cm(-3) and the applied current of 300 mA. The differential pulse voltammetry using glassy carbon electrode was performed for the first time in the above-mentioned content of electrolyte for the nine concentration of azithromycin (0.075-0.675 mg cm(-3)) giving the limits of azithromycin detection and of quantification as: LOD 0.044 mg cm(-3) and LOQ 0.145 mg cm(-3). The calibration curve was constructed enabling the electrolyte analysis during its electrodegradation process. The electrolyte was analyzed by high-performance liquid chromatography and electrospray ionization time-of-flight mass spectrometry. The elec...trooxidation products were identified and after 180 min there was no azithromycin in the electrolyte while TOC analysis showed that 79% of azithromycin was mineralized. The proposed degradation scheme is presented.
Кључне речи:
Azithromycin / Electrocatalytic degradation / Ti/RuO2 / ToF LC-MS / TOC analysisИзвор:
Chemical Papers, 2017, 71, 7, 1217-1224Издавач:
- Springer International Publishing Ag, Cham
Финансирање / пројекти:
- Проучавање синтезе, структуре и активности органских једињења природног и синтетског порекла (RS-MESTD-Basic Research (BR or ON)-172013)
- Нов приступ дизајнирању материјала за конверзију и складиштење енергије (RS-MESTD-Basic Research (BR or ON)-172060)
DOI: 10.1007/s11696-016-0115-2
ISSN: 2585-7290
WoS: 000403321900004
Scopus: 2-s2.0-85010754430
Институција/група
Tehnološko-metalurški fakultetTY - JOUR AU - Radosavljević, Kristina D. AU - Lović, Jelena AU - Mijin, Dušan AU - Petrović, Slobodan AU - Jadranin, Milka AU - Mladenović, Aleksandar R. AU - Avramov-Ivić, Milka PY - 2017 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3685 AB - The electrodegradation of azithromycin was studied by its indirect oxidation using dimensionally stable Ti/RuO2 anode as catalyst in the electrolyte containing methanol, 0.05 M NaHCO3, sodium chloride and deionized water. The optimal conditions for galvanostatic electrodegradation for the azithromycin concentration of 0.472 mg cm(-3) were found to be NaCl concentration of 7 mg cm(-3) and the applied current of 300 mA. The differential pulse voltammetry using glassy carbon electrode was performed for the first time in the above-mentioned content of electrolyte for the nine concentration of azithromycin (0.075-0.675 mg cm(-3)) giving the limits of azithromycin detection and of quantification as: LOD 0.044 mg cm(-3) and LOQ 0.145 mg cm(-3). The calibration curve was constructed enabling the electrolyte analysis during its electrodegradation process. The electrolyte was analyzed by high-performance liquid chromatography and electrospray ionization time-of-flight mass spectrometry. The electrooxidation products were identified and after 180 min there was no azithromycin in the electrolyte while TOC analysis showed that 79% of azithromycin was mineralized. The proposed degradation scheme is presented. PB - Springer International Publishing Ag, Cham T2 - Chemical Papers T1 - Degradation of azithromycin using Ti/RuO2 anode as catalyst followed by DPV, HPLC-UV and MS analysis EP - 1224 IS - 7 SP - 1217 VL - 71 DO - 10.1007/s11696-016-0115-2 ER -
@article{ author = "Radosavljević, Kristina D. and Lović, Jelena and Mijin, Dušan and Petrović, Slobodan and Jadranin, Milka and Mladenović, Aleksandar R. and Avramov-Ivić, Milka", year = "2017", abstract = "The electrodegradation of azithromycin was studied by its indirect oxidation using dimensionally stable Ti/RuO2 anode as catalyst in the electrolyte containing methanol, 0.05 M NaHCO3, sodium chloride and deionized water. The optimal conditions for galvanostatic electrodegradation for the azithromycin concentration of 0.472 mg cm(-3) were found to be NaCl concentration of 7 mg cm(-3) and the applied current of 300 mA. The differential pulse voltammetry using glassy carbon electrode was performed for the first time in the above-mentioned content of electrolyte for the nine concentration of azithromycin (0.075-0.675 mg cm(-3)) giving the limits of azithromycin detection and of quantification as: LOD 0.044 mg cm(-3) and LOQ 0.145 mg cm(-3). The calibration curve was constructed enabling the electrolyte analysis during its electrodegradation process. The electrolyte was analyzed by high-performance liquid chromatography and electrospray ionization time-of-flight mass spectrometry. The electrooxidation products were identified and after 180 min there was no azithromycin in the electrolyte while TOC analysis showed that 79% of azithromycin was mineralized. The proposed degradation scheme is presented.", publisher = "Springer International Publishing Ag, Cham", journal = "Chemical Papers", title = "Degradation of azithromycin using Ti/RuO2 anode as catalyst followed by DPV, HPLC-UV and MS analysis", pages = "1224-1217", number = "7", volume = "71", doi = "10.1007/s11696-016-0115-2" }
Radosavljević, K. D., Lović, J., Mijin, D., Petrović, S., Jadranin, M., Mladenović, A. R.,& Avramov-Ivić, M.. (2017). Degradation of azithromycin using Ti/RuO2 anode as catalyst followed by DPV, HPLC-UV and MS analysis. in Chemical Papers Springer International Publishing Ag, Cham., 71(7), 1217-1224. https://doi.org/10.1007/s11696-016-0115-2
Radosavljević KD, Lović J, Mijin D, Petrović S, Jadranin M, Mladenović AR, Avramov-Ivić M. Degradation of azithromycin using Ti/RuO2 anode as catalyst followed by DPV, HPLC-UV and MS analysis. in Chemical Papers. 2017;71(7):1217-1224. doi:10.1007/s11696-016-0115-2 .
Radosavljević, Kristina D., Lović, Jelena, Mijin, Dušan, Petrović, Slobodan, Jadranin, Milka, Mladenović, Aleksandar R., Avramov-Ivić, Milka, "Degradation of azithromycin using Ti/RuO2 anode as catalyst followed by DPV, HPLC-UV and MS analysis" in Chemical Papers, 71, no. 7 (2017):1217-1224, https://doi.org/10.1007/s11696-016-0115-2 . .