Silver/poly(vinyl alcohol)/chitosan/graphene hydrogels - Synthesis, biological and physicochemical properties and silver release kinetics
Само за регистроване кориснике
2018
Аутори
Nešović, KatarinaJanković, Ana
Kojić, Vesna
Vukašinović-Sekulić, Maja
Perić-Grujić, Aleksandra
Rhee, Kyong Yop
Mišković-Stanković, Vesna
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
This study presents the synthesis of novel silver/poly(vinyl alcohol)/chitosan/graphene (Ag/PVA/CHI/Gr) nanocomposite hydrogels by in situ electrochemical reduction of silver ions in the hydrogel matrix and their thorough characterization by UV-visible and Raman spectroscopies, field-emission scanning electron microscopy (FE-SEM), X-ray photoelectron spectroscopy (XPS), and silver release measurements. The influence of chitosan content on the incorporation and stabilization of silver nanoparticles (AgNPs) was investigated, and we found that hydrogels with higher chitosan content contain higher amounts of AgNPs. In addition, the cytotoxicity and antibacterial activity of Ag/PVA/CHI/Gr nanocomposite hydrogels were evaluated. Based on in vitro investigations, the obtained materials exhibit diffusion-controlled release profiles over 28 days, strong antibacterial activity against Staphylococcus aureus and Escherichia coli bacterial strains, and no cytotoxicity toward human and mice fibrobla...st cell lines.
Кључне речи:
Polymer-matrix composites (PMCs) / Nano-structures / Surface properties / Electron microscopyИзвор:
Composites Part B-Engineering, 2018, 154, 175-185Издавач:
- Elsevier Sci Ltd, Oxford
Финансирање / пројекти:
- Синтеза, развој технологија добијања и примена наноструктурних мултифункционалних материјала дефинисаних својстава (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-45019)
- Basic Science Research Program of the Ministry of Education, Science and Technology of Korea [2018R1A2B5A02023190]
DOI: 10.1016/j.compositesb.2018.08.005
ISSN: 1359-8368
WoS: 000449904300018
Scopus: 2-s2.0-85051107977
Колекције
Институција/група
Tehnološko-metalurški fakultetTY - JOUR AU - Nešović, Katarina AU - Janković, Ana AU - Kojić, Vesna AU - Vukašinović-Sekulić, Maja AU - Perić-Grujić, Aleksandra AU - Rhee, Kyong Yop AU - Mišković-Stanković, Vesna PY - 2018 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3942 AB - This study presents the synthesis of novel silver/poly(vinyl alcohol)/chitosan/graphene (Ag/PVA/CHI/Gr) nanocomposite hydrogels by in situ electrochemical reduction of silver ions in the hydrogel matrix and their thorough characterization by UV-visible and Raman spectroscopies, field-emission scanning electron microscopy (FE-SEM), X-ray photoelectron spectroscopy (XPS), and silver release measurements. The influence of chitosan content on the incorporation and stabilization of silver nanoparticles (AgNPs) was investigated, and we found that hydrogels with higher chitosan content contain higher amounts of AgNPs. In addition, the cytotoxicity and antibacterial activity of Ag/PVA/CHI/Gr nanocomposite hydrogels were evaluated. Based on in vitro investigations, the obtained materials exhibit diffusion-controlled release profiles over 28 days, strong antibacterial activity against Staphylococcus aureus and Escherichia coli bacterial strains, and no cytotoxicity toward human and mice fibroblast cell lines. PB - Elsevier Sci Ltd, Oxford T2 - Composites Part B-Engineering T1 - Silver/poly(vinyl alcohol)/chitosan/graphene hydrogels - Synthesis, biological and physicochemical properties and silver release kinetics EP - 185 SP - 175 VL - 154 DO - 10.1016/j.compositesb.2018.08.005 ER -
@article{ author = "Nešović, Katarina and Janković, Ana and Kojić, Vesna and Vukašinović-Sekulić, Maja and Perić-Grujić, Aleksandra and Rhee, Kyong Yop and Mišković-Stanković, Vesna", year = "2018", abstract = "This study presents the synthesis of novel silver/poly(vinyl alcohol)/chitosan/graphene (Ag/PVA/CHI/Gr) nanocomposite hydrogels by in situ electrochemical reduction of silver ions in the hydrogel matrix and their thorough characterization by UV-visible and Raman spectroscopies, field-emission scanning electron microscopy (FE-SEM), X-ray photoelectron spectroscopy (XPS), and silver release measurements. The influence of chitosan content on the incorporation and stabilization of silver nanoparticles (AgNPs) was investigated, and we found that hydrogels with higher chitosan content contain higher amounts of AgNPs. In addition, the cytotoxicity and antibacterial activity of Ag/PVA/CHI/Gr nanocomposite hydrogels were evaluated. Based on in vitro investigations, the obtained materials exhibit diffusion-controlled release profiles over 28 days, strong antibacterial activity against Staphylococcus aureus and Escherichia coli bacterial strains, and no cytotoxicity toward human and mice fibroblast cell lines.", publisher = "Elsevier Sci Ltd, Oxford", journal = "Composites Part B-Engineering", title = "Silver/poly(vinyl alcohol)/chitosan/graphene hydrogels - Synthesis, biological and physicochemical properties and silver release kinetics", pages = "185-175", volume = "154", doi = "10.1016/j.compositesb.2018.08.005" }
Nešović, K., Janković, A., Kojić, V., Vukašinović-Sekulić, M., Perić-Grujić, A., Rhee, K. Y.,& Mišković-Stanković, V.. (2018). Silver/poly(vinyl alcohol)/chitosan/graphene hydrogels - Synthesis, biological and physicochemical properties and silver release kinetics. in Composites Part B-Engineering Elsevier Sci Ltd, Oxford., 154, 175-185. https://doi.org/10.1016/j.compositesb.2018.08.005
Nešović K, Janković A, Kojić V, Vukašinović-Sekulić M, Perić-Grujić A, Rhee KY, Mišković-Stanković V. Silver/poly(vinyl alcohol)/chitosan/graphene hydrogels - Synthesis, biological and physicochemical properties and silver release kinetics. in Composites Part B-Engineering. 2018;154:175-185. doi:10.1016/j.compositesb.2018.08.005 .
Nešović, Katarina, Janković, Ana, Kojić, Vesna, Vukašinović-Sekulić, Maja, Perić-Grujić, Aleksandra, Rhee, Kyong Yop, Mišković-Stanković, Vesna, "Silver/poly(vinyl alcohol)/chitosan/graphene hydrogels - Synthesis, biological and physicochemical properties and silver release kinetics" in Composites Part B-Engineering, 154 (2018):175-185, https://doi.org/10.1016/j.compositesb.2018.08.005 . .