Electrochemical and biocompatibility examinations of high-pressure torsion processed titanium and Ti-13Nb-13Zr alloy
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2018
Authors
Dimić, IvanaCvijović-Alagić, Ivana
Hohenwarter, Anton
Pippan, Reinhard
Kojić, Vesna
Bajat, Jelena
Rakin, Marko
Article (Published version)
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The purpose of this study was to estimate the electrochemical behavior and biocompatibility of ultrafine-grained (UFG) commercially pure titanium (CPTi) and Ti-13Nb-13Zr (TNZ) alloy obtained by high-pressure torsion process. Electrochemical behavior of materials in artificial saliva at 37 degrees C was evaluated by potentiodynamic polarization tests and electrochemical impedance spectroscopy (EIS), and the obtained results indicated that UFG TNZ alloy showed corrosion current density (j(corr)=53 +/- 5 nA cm(-2)) which was 2 times lower compared to coarse-grained (CG) TNZ alloy (j(corr)=110 +/- 12 nA cm(-2)) and higher corrosion resistance, while UFG CPTi and CPTi showed approximately the same corrosion rate (mean j(corr) approximate to 38-40 nA cm(-2)). Static immersion test in artificial saliva, performed in this study, showed that the released ion concentrations from UFG materials were more than 10 times lower than the permitted concentration (the highest released Ti ion concentratio...n from UFG CPTi and UFG TNZ alloy was 1.12 and 1.28 ppb, respectively, while permitted concentration was 15.5 ppb). The in vitro cytotoxicity tests, as the initial phase of the biocompatibility evaluation, showed that the fraction of surviving cells in all examined materials was much higher compared to the control sample and hence demonstrated absence of cytotoxicity and an increase of fibroblast cells adhesion on UFG materials surfaces. UFG CPTi and UFG TNZ alloy can be considered as promising materials for applications in dentistry due to high corrosion resistance and outstanding biocompatibility which were shown in this study.
Keywords:
high-pressure torsion / ultrafine-grained alloy / Ti-13Nb-13Zr / biocompatibility / corrosion resistanceSource:
Journal of Biomedical Materials Research Part B-Applied Biomaterials, 2018, 106, 3, 1097-1107Publisher:
- Wiley, Hoboken
Funding / projects:
- Novel encapsulation and enzyme technologies for designing of new biocatalysts and biologically active compounds targeting enhancement of food quality, safety and competitiveness (RS-MESTD-Integrated and Interdisciplinary Research (IIR or III)-46010)
- Micromechanical criteria of damage and fracture (RS-MESTD-Basic Research (BR or ON)-174004)
DOI: 10.1002/jbm.b.33919
ISSN: 1552-4973
PubMed: 28503902
WoS: 000427068200016
Scopus: 2-s2.0-85019206964
Institution/Community
Tehnološko-metalurški fakultetTY - JOUR AU - Dimić, Ivana AU - Cvijović-Alagić, Ivana AU - Hohenwarter, Anton AU - Pippan, Reinhard AU - Kojić, Vesna AU - Bajat, Jelena AU - Rakin, Marko PY - 2018 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3963 AB - The purpose of this study was to estimate the electrochemical behavior and biocompatibility of ultrafine-grained (UFG) commercially pure titanium (CPTi) and Ti-13Nb-13Zr (TNZ) alloy obtained by high-pressure torsion process. Electrochemical behavior of materials in artificial saliva at 37 degrees C was evaluated by potentiodynamic polarization tests and electrochemical impedance spectroscopy (EIS), and the obtained results indicated that UFG TNZ alloy showed corrosion current density (j(corr)=53 +/- 5 nA cm(-2)) which was 2 times lower compared to coarse-grained (CG) TNZ alloy (j(corr)=110 +/- 12 nA cm(-2)) and higher corrosion resistance, while UFG CPTi and CPTi showed approximately the same corrosion rate (mean j(corr) approximate to 38-40 nA cm(-2)). Static immersion test in artificial saliva, performed in this study, showed that the released ion concentrations from UFG materials were more than 10 times lower than the permitted concentration (the highest released Ti ion concentration from UFG CPTi and UFG TNZ alloy was 1.12 and 1.28 ppb, respectively, while permitted concentration was 15.5 ppb). The in vitro cytotoxicity tests, as the initial phase of the biocompatibility evaluation, showed that the fraction of surviving cells in all examined materials was much higher compared to the control sample and hence demonstrated absence of cytotoxicity and an increase of fibroblast cells adhesion on UFG materials surfaces. UFG CPTi and UFG TNZ alloy can be considered as promising materials for applications in dentistry due to high corrosion resistance and outstanding biocompatibility which were shown in this study. PB - Wiley, Hoboken T2 - Journal of Biomedical Materials Research Part B-Applied Biomaterials T1 - Electrochemical and biocompatibility examinations of high-pressure torsion processed titanium and Ti-13Nb-13Zr alloy EP - 1107 IS - 3 SP - 1097 VL - 106 DO - 10.1002/jbm.b.33919 ER -
@article{ author = "Dimić, Ivana and Cvijović-Alagić, Ivana and Hohenwarter, Anton and Pippan, Reinhard and Kojić, Vesna and Bajat, Jelena and Rakin, Marko", year = "2018", abstract = "The purpose of this study was to estimate the electrochemical behavior and biocompatibility of ultrafine-grained (UFG) commercially pure titanium (CPTi) and Ti-13Nb-13Zr (TNZ) alloy obtained by high-pressure torsion process. Electrochemical behavior of materials in artificial saliva at 37 degrees C was evaluated by potentiodynamic polarization tests and electrochemical impedance spectroscopy (EIS), and the obtained results indicated that UFG TNZ alloy showed corrosion current density (j(corr)=53 +/- 5 nA cm(-2)) which was 2 times lower compared to coarse-grained (CG) TNZ alloy (j(corr)=110 +/- 12 nA cm(-2)) and higher corrosion resistance, while UFG CPTi and CPTi showed approximately the same corrosion rate (mean j(corr) approximate to 38-40 nA cm(-2)). Static immersion test in artificial saliva, performed in this study, showed that the released ion concentrations from UFG materials were more than 10 times lower than the permitted concentration (the highest released Ti ion concentration from UFG CPTi and UFG TNZ alloy was 1.12 and 1.28 ppb, respectively, while permitted concentration was 15.5 ppb). The in vitro cytotoxicity tests, as the initial phase of the biocompatibility evaluation, showed that the fraction of surviving cells in all examined materials was much higher compared to the control sample and hence demonstrated absence of cytotoxicity and an increase of fibroblast cells adhesion on UFG materials surfaces. UFG CPTi and UFG TNZ alloy can be considered as promising materials for applications in dentistry due to high corrosion resistance and outstanding biocompatibility which were shown in this study.", publisher = "Wiley, Hoboken", journal = "Journal of Biomedical Materials Research Part B-Applied Biomaterials", title = "Electrochemical and biocompatibility examinations of high-pressure torsion processed titanium and Ti-13Nb-13Zr alloy", pages = "1107-1097", number = "3", volume = "106", doi = "10.1002/jbm.b.33919" }
Dimić, I., Cvijović-Alagić, I., Hohenwarter, A., Pippan, R., Kojić, V., Bajat, J.,& Rakin, M.. (2018). Electrochemical and biocompatibility examinations of high-pressure torsion processed titanium and Ti-13Nb-13Zr alloy. in Journal of Biomedical Materials Research Part B-Applied Biomaterials Wiley, Hoboken., 106(3), 1097-1107. https://doi.org/10.1002/jbm.b.33919
Dimić I, Cvijović-Alagić I, Hohenwarter A, Pippan R, Kojić V, Bajat J, Rakin M. Electrochemical and biocompatibility examinations of high-pressure torsion processed titanium and Ti-13Nb-13Zr alloy. in Journal of Biomedical Materials Research Part B-Applied Biomaterials. 2018;106(3):1097-1107. doi:10.1002/jbm.b.33919 .
Dimić, Ivana, Cvijović-Alagić, Ivana, Hohenwarter, Anton, Pippan, Reinhard, Kojić, Vesna, Bajat, Jelena, Rakin, Marko, "Electrochemical and biocompatibility examinations of high-pressure torsion processed titanium and Ti-13Nb-13Zr alloy" in Journal of Biomedical Materials Research Part B-Applied Biomaterials, 106, no. 3 (2018):1097-1107, https://doi.org/10.1002/jbm.b.33919 . .