Fibrous systems with programmed biological-activity and their application in medical practice
Abstract
An effective two-stage method for obtaining both biologically activated fibres with antibacterial and anaesthetic activity and biologically activated complex fibres -insulin as an artificial store of insulin has been developed. The first stage involves the formation of reactive functional groups by chemical modification, followed by the second stage where the fibres are modified with chemotherapeutic agent solutions. This paper presents the results of obtaining biologically activated fibres with antibacterial and anaesthetic activity as well as an artificial store of insulin in the form of complex ion-exchanged fibre-insulin. The level of immobilisation of the drug in the antibacterial fibre amounts to 140 mg of gentamicin sulphate per 1 g of fibres, in the anaesthetic fibre 180 mg of procaine hydrochloride per 1 g of fibres, and in the fibrous store of insulin 800 mg of insulin per 1 g of fibres. 2002
Source:
Autex Research Journal, 2002, 2, 2, 78-84Institution/Community
Tehnološko-metalurški fakultetTY - JOUR AU - Škundrić, Petar AU - Medović, Adela AU - Kostić, Mirjana PY - 2002 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/407 AB - An effective two-stage method for obtaining both biologically activated fibres with antibacterial and anaesthetic activity and biologically activated complex fibres -insulin as an artificial store of insulin has been developed. The first stage involves the formation of reactive functional groups by chemical modification, followed by the second stage where the fibres are modified with chemotherapeutic agent solutions. This paper presents the results of obtaining biologically activated fibres with antibacterial and anaesthetic activity as well as an artificial store of insulin in the form of complex ion-exchanged fibre-insulin. The level of immobilisation of the drug in the antibacterial fibre amounts to 140 mg of gentamicin sulphate per 1 g of fibres, in the anaesthetic fibre 180 mg of procaine hydrochloride per 1 g of fibres, and in the fibrous store of insulin 800 mg of insulin per 1 g of fibres. 2002 T2 - Autex Research Journal T1 - Fibrous systems with programmed biological-activity and their application in medical practice EP - 84 IS - 2 SP - 78 VL - 2 UR - https://hdl.handle.net/21.15107/rcub_technorep_407 ER -
@article{ author = "Škundrić, Petar and Medović, Adela and Kostić, Mirjana", year = "2002", abstract = "An effective two-stage method for obtaining both biologically activated fibres with antibacterial and anaesthetic activity and biologically activated complex fibres -insulin as an artificial store of insulin has been developed. The first stage involves the formation of reactive functional groups by chemical modification, followed by the second stage where the fibres are modified with chemotherapeutic agent solutions. This paper presents the results of obtaining biologically activated fibres with antibacterial and anaesthetic activity as well as an artificial store of insulin in the form of complex ion-exchanged fibre-insulin. The level of immobilisation of the drug in the antibacterial fibre amounts to 140 mg of gentamicin sulphate per 1 g of fibres, in the anaesthetic fibre 180 mg of procaine hydrochloride per 1 g of fibres, and in the fibrous store of insulin 800 mg of insulin per 1 g of fibres. 2002", journal = "Autex Research Journal", title = "Fibrous systems with programmed biological-activity and their application in medical practice", pages = "84-78", number = "2", volume = "2", url = "https://hdl.handle.net/21.15107/rcub_technorep_407" }
Škundrić, P., Medović, A.,& Kostić, M.. (2002). Fibrous systems with programmed biological-activity and their application in medical practice. in Autex Research Journal, 2(2), 78-84. https://hdl.handle.net/21.15107/rcub_technorep_407
Škundrić P, Medović A, Kostić M. Fibrous systems with programmed biological-activity and their application in medical practice. in Autex Research Journal. 2002;2(2):78-84. https://hdl.handle.net/21.15107/rcub_technorep_407 .
Škundrić, Petar, Medović, Adela, Kostić, Mirjana, "Fibrous systems with programmed biological-activity and their application in medical practice" in Autex Research Journal, 2, no. 2 (2002):78-84, https://hdl.handle.net/21.15107/rcub_technorep_407 .