Antibacterial activity of thymol/carvacrol and clinoptilolite composites prepared by supercritical solvent impregnation
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2021
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Novel composites based on natural zeolite-clinoptilolite and monoterpene phenols-thymol and carvacrol were prepared by supercritical solvent impregnation (SSI) in supercritical carbon dioxide (scCO(2)) at 30 MPa and 35 degrees C during 18 h. The content of phenols in composites (thymol-23.0 and carvacrol-19.1 wt%) was determined using both C,H,N and thermal analysis (TGA); interactions of the phenols with the zeolite lattice studied by Fourier transform infrared spectroscopy (FTIR) and powder X-ray diffraction (PXRD) showed that the zeolite lattice was preserved in the composites. The composites exhibited antibacterial activity toward Gram-negative bacteria Escherichia coli DSM 498 and Gram-positive bacteria Staphylococcus aureus ATCC 25923 in different water media (phosphate buffer solution, spring water and lake water). After 1 h carvacrol-containing clinoptilolite showed better antibacterial activity than composite with thymol. Both composites expressed bactericidal effect after 24 ...h of contact. Leaching of the phenols from composite in water was more pronounced from thymol (22.7-32.1%) than for carvacrol (6.2-8.9%) suggesting influence of steric effect on the desorption process.
Ključne reči:
Zeolite / Thymol / Carvacrol / Supercritical solvent impregnation / Supercritical carbon dioxide / Antibacterial activityIzvor:
Journal of Porous Materials, 2021, 28, 5, 1577-1584Finansiranje / projekti:
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200135 (Univerzitet u Beogradu, Tehnološko-metalurški fakultet) (RS-MESTD-inst-2020-200135)
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200287 (Inovacioni centar Tehnološko-metalurškog fakulteta u Beogradu doo) (RS-MESTD-inst-2020-200287)
DOI: 10.1007/s10934-021-01107-y
ISSN: 1380-2224
WoS: 000662119800001
Scopus: 2-s2.0-85108177549
Institucija/grupa
Inovacioni centarTY - JOUR AU - Dikić, Jelena AU - Lukić, Ivana AU - Pajnik, Jelena AU - Pavlovic, Jelena AU - Hrenovic, Jasna AU - Rajić, Nevenka PY - 2021 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4915 AB - Novel composites based on natural zeolite-clinoptilolite and monoterpene phenols-thymol and carvacrol were prepared by supercritical solvent impregnation (SSI) in supercritical carbon dioxide (scCO(2)) at 30 MPa and 35 degrees C during 18 h. The content of phenols in composites (thymol-23.0 and carvacrol-19.1 wt%) was determined using both C,H,N and thermal analysis (TGA); interactions of the phenols with the zeolite lattice studied by Fourier transform infrared spectroscopy (FTIR) and powder X-ray diffraction (PXRD) showed that the zeolite lattice was preserved in the composites. The composites exhibited antibacterial activity toward Gram-negative bacteria Escherichia coli DSM 498 and Gram-positive bacteria Staphylococcus aureus ATCC 25923 in different water media (phosphate buffer solution, spring water and lake water). After 1 h carvacrol-containing clinoptilolite showed better antibacterial activity than composite with thymol. Both composites expressed bactericidal effect after 24 h of contact. Leaching of the phenols from composite in water was more pronounced from thymol (22.7-32.1%) than for carvacrol (6.2-8.9%) suggesting influence of steric effect on the desorption process. T2 - Journal of Porous Materials T1 - Antibacterial activity of thymol/carvacrol and clinoptilolite composites prepared by supercritical solvent impregnation EP - 1584 IS - 5 SP - 1577 VL - 28 DO - 10.1007/s10934-021-01107-y ER -
@article{ author = "Dikić, Jelena and Lukić, Ivana and Pajnik, Jelena and Pavlovic, Jelena and Hrenovic, Jasna and Rajić, Nevenka", year = "2021", abstract = "Novel composites based on natural zeolite-clinoptilolite and monoterpene phenols-thymol and carvacrol were prepared by supercritical solvent impregnation (SSI) in supercritical carbon dioxide (scCO(2)) at 30 MPa and 35 degrees C during 18 h. The content of phenols in composites (thymol-23.0 and carvacrol-19.1 wt%) was determined using both C,H,N and thermal analysis (TGA); interactions of the phenols with the zeolite lattice studied by Fourier transform infrared spectroscopy (FTIR) and powder X-ray diffraction (PXRD) showed that the zeolite lattice was preserved in the composites. The composites exhibited antibacterial activity toward Gram-negative bacteria Escherichia coli DSM 498 and Gram-positive bacteria Staphylococcus aureus ATCC 25923 in different water media (phosphate buffer solution, spring water and lake water). After 1 h carvacrol-containing clinoptilolite showed better antibacterial activity than composite with thymol. Both composites expressed bactericidal effect after 24 h of contact. Leaching of the phenols from composite in water was more pronounced from thymol (22.7-32.1%) than for carvacrol (6.2-8.9%) suggesting influence of steric effect on the desorption process.", journal = "Journal of Porous Materials", title = "Antibacterial activity of thymol/carvacrol and clinoptilolite composites prepared by supercritical solvent impregnation", pages = "1584-1577", number = "5", volume = "28", doi = "10.1007/s10934-021-01107-y" }
Dikić, J., Lukić, I., Pajnik, J., Pavlovic, J., Hrenovic, J.,& Rajić, N.. (2021). Antibacterial activity of thymol/carvacrol and clinoptilolite composites prepared by supercritical solvent impregnation. in Journal of Porous Materials, 28(5), 1577-1584. https://doi.org/10.1007/s10934-021-01107-y
Dikić J, Lukić I, Pajnik J, Pavlovic J, Hrenovic J, Rajić N. Antibacterial activity of thymol/carvacrol and clinoptilolite composites prepared by supercritical solvent impregnation. in Journal of Porous Materials. 2021;28(5):1577-1584. doi:10.1007/s10934-021-01107-y .
Dikić, Jelena, Lukić, Ivana, Pajnik, Jelena, Pavlovic, Jelena, Hrenovic, Jasna, Rajić, Nevenka, "Antibacterial activity of thymol/carvacrol and clinoptilolite composites prepared by supercritical solvent impregnation" in Journal of Porous Materials, 28, no. 5 (2021):1577-1584, https://doi.org/10.1007/s10934-021-01107-y . .