Dandelion seeds as a new and valuable source of bioactive extracts obtained using the supercritical fluid extraction technique
Samo za registrovane korisnike
2022
Autori
Milovanovic, StojaGrzegorczyk, Agnieszka
Świątek, Łukasz
Dębczak, Agnieszka
Tyskiewicz, Katarzyna
Konkol, Marcin
Članak u časopisu (Objavljena verzija)
Metapodaci
Prikaz svih podataka o dokumentuApstrakt
The present study was intended to explore dandelion seeds as a new source of biologically active constituents using an environmentally friendly extraction technique. The process-function relationships were determined by following the influence of temperature (40 and 60 °C) and pressure (from 100 to 450 bar) on the amount of separated extract, its density, composition, and bioactivity. It was shown that the supercritical CO2-assisted technique enables the separation of 0.6–25.0% extract having a density in a range of 827–941 kg/m3. Extracts contained a high amount of unsaturated fatty acids (89.9–90.6%) including linoleic acid (71%) and α-linolenic acid (up to 0.9%), as well as phenolic (5.5–12.1 mg GAE/g) and flavonoid compounds (208.6–564.5 μg QE/g). The antioxidant activity test showed that 20 mg/mL extract solutions inhibit 26.0–64.4% DPPH radical. In addition, extracts showed significant antimicrobial activity, especially against Gram-positive Bacillus subtilis and Micrococcus lute...us. There was no cytotoxic effect on normal green monkey kidney cells and human skin fibroblasts nor on hypopharyngeal cancer, cervical adenocarcinoma, and colon cancer cells. The study indicated the possible safe application of bioactive dandelion seeds extract in the pharmaceutical, food, and cosmetic industry.
Ključne reči:
Antimicrobial activity / Antioxidant activity / Fatty acid composition / Supercritical carbon dioxide extraction / Taraxacum officinale / Total phenolic contentIzvor:
Sustainable Chemistry and Pharmacy, 2022, 29, 100796-Izdavač:
- Elsevier B.V.
Finansiranje / projekti:
- Ministarstvo nauke, tehnološkog razvoja i inovacija Republike Srbije, institucionalno finansiranje - 200135 (Univerzitet u Beogradu, Tehnološko-metalurški fakultet) (RS-MESTD-inst-2020-200135)
DOI: 10.1016/j.scp.2022.100796
ISSN: 2352-5541
WoS: 00084199420000
Scopus: 2-s2.0-85135525561
Institucija/grupa
Tehnološko-metalurški fakultetTY - JOUR AU - Milovanovic, Stoja AU - Grzegorczyk, Agnieszka AU - Świątek, Łukasz AU - Dębczak, Agnieszka AU - Tyskiewicz, Katarzyna AU - Konkol, Marcin PY - 2022 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5163 AB - The present study was intended to explore dandelion seeds as a new source of biologically active constituents using an environmentally friendly extraction technique. The process-function relationships were determined by following the influence of temperature (40 and 60 °C) and pressure (from 100 to 450 bar) on the amount of separated extract, its density, composition, and bioactivity. It was shown that the supercritical CO2-assisted technique enables the separation of 0.6–25.0% extract having a density in a range of 827–941 kg/m3. Extracts contained a high amount of unsaturated fatty acids (89.9–90.6%) including linoleic acid (71%) and α-linolenic acid (up to 0.9%), as well as phenolic (5.5–12.1 mg GAE/g) and flavonoid compounds (208.6–564.5 μg QE/g). The antioxidant activity test showed that 20 mg/mL extract solutions inhibit 26.0–64.4% DPPH radical. In addition, extracts showed significant antimicrobial activity, especially against Gram-positive Bacillus subtilis and Micrococcus luteus. There was no cytotoxic effect on normal green monkey kidney cells and human skin fibroblasts nor on hypopharyngeal cancer, cervical adenocarcinoma, and colon cancer cells. The study indicated the possible safe application of bioactive dandelion seeds extract in the pharmaceutical, food, and cosmetic industry. PB - Elsevier B.V. T2 - Sustainable Chemistry and Pharmacy T1 - Dandelion seeds as a new and valuable source of bioactive extracts obtained using the supercritical fluid extraction technique SP - 100796 VL - 29 DO - 10.1016/j.scp.2022.100796 ER -
@article{ author = "Milovanovic, Stoja and Grzegorczyk, Agnieszka and Świątek, Łukasz and Dębczak, Agnieszka and Tyskiewicz, Katarzyna and Konkol, Marcin", year = "2022", abstract = "The present study was intended to explore dandelion seeds as a new source of biologically active constituents using an environmentally friendly extraction technique. The process-function relationships were determined by following the influence of temperature (40 and 60 °C) and pressure (from 100 to 450 bar) on the amount of separated extract, its density, composition, and bioactivity. It was shown that the supercritical CO2-assisted technique enables the separation of 0.6–25.0% extract having a density in a range of 827–941 kg/m3. Extracts contained a high amount of unsaturated fatty acids (89.9–90.6%) including linoleic acid (71%) and α-linolenic acid (up to 0.9%), as well as phenolic (5.5–12.1 mg GAE/g) and flavonoid compounds (208.6–564.5 μg QE/g). The antioxidant activity test showed that 20 mg/mL extract solutions inhibit 26.0–64.4% DPPH radical. In addition, extracts showed significant antimicrobial activity, especially against Gram-positive Bacillus subtilis and Micrococcus luteus. There was no cytotoxic effect on normal green monkey kidney cells and human skin fibroblasts nor on hypopharyngeal cancer, cervical adenocarcinoma, and colon cancer cells. The study indicated the possible safe application of bioactive dandelion seeds extract in the pharmaceutical, food, and cosmetic industry.", publisher = "Elsevier B.V.", journal = "Sustainable Chemistry and Pharmacy", title = "Dandelion seeds as a new and valuable source of bioactive extracts obtained using the supercritical fluid extraction technique", pages = "100796", volume = "29", doi = "10.1016/j.scp.2022.100796" }
Milovanovic, S., Grzegorczyk, A., Świątek, Ł., Dębczak, A., Tyskiewicz, K.,& Konkol, M.. (2022). Dandelion seeds as a new and valuable source of bioactive extracts obtained using the supercritical fluid extraction technique. in Sustainable Chemistry and Pharmacy Elsevier B.V.., 29, 100796. https://doi.org/10.1016/j.scp.2022.100796
Milovanovic S, Grzegorczyk A, Świątek Ł, Dębczak A, Tyskiewicz K, Konkol M. Dandelion seeds as a new and valuable source of bioactive extracts obtained using the supercritical fluid extraction technique. in Sustainable Chemistry and Pharmacy. 2022;29:100796. doi:10.1016/j.scp.2022.100796 .
Milovanovic, Stoja, Grzegorczyk, Agnieszka, Świątek, Łukasz, Dębczak, Agnieszka, Tyskiewicz, Katarzyna, Konkol, Marcin, "Dandelion seeds as a new and valuable source of bioactive extracts obtained using the supercritical fluid extraction technique" in Sustainable Chemistry and Pharmacy, 29 (2022):100796, https://doi.org/10.1016/j.scp.2022.100796 . .