Ultrasound-assisted extraction of biologically active compounds and their successive concentration by using membrane processes
Само за регистроване кориснике
2019
Аутори
Trojanowska, AnnaTsibranska, Iren
Dzhonova, Daniela
Wroblewska, Michalina
Haponska, Monika
Jovančić, Petar
Marturano, Valentina
Tylkowski, Bartosz
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
Sideritis scardica and Sideritis syriaca are considered highly valuable plant materials and their total polyphenols (TP) and total flavonoids (TF) extracts can be employed in nutraceutics and cosmetics. A two-step process was proposed consisting in the ultrasound-assisted extraction (UAE) and concentration of the biologically active compounds via nanofiltration (NF). An extensive comparison between UAE and conventional high-temperature stirring was performed, taking into account the effect of process parameters such as solvent, temperature and ultrasonication. In terms of radical scavenging activity and time optimization, UAE was found more effective, providing – after only 1 h – extraction yields comparable to 20 h of the conventional thermo-mechanical method. The extract was then concentrated by nanofiltration in tangential mode at 20 bar using 300 and 500 Da cut-off Duramem membranes. Permeate and rejection flux was monitored during the filtration process. The lower molecular weight... membrane showed higher permeability towards TP and TF and contributed to a more stable flux and lower fouling processes. To predict operational drawbacks, computational fluid dynamic simulations were performed to model the complex rotational flow occurring during membrane filtration.
Кључне речи:
Flavonoids / Organic solvent nanofiltration / Polyphenols / Sideritis (Pirin mountain tea) / Ultrasound-assisted extractionИзвор:
Chemical Engineering Research and Design, 2019, 147, 378-389Издавач:
- Institution of Chemical Engineers
Финансирање / пројекти:
- Bulgarian National Science Fund – Ministry of Education and Science under Contract DN 07/11-15.12.2016.
- The EURECAT internal research program: Plan of Research and Innovation 2018 (PRI 2018).
- ACCIÓ - Regional Agency for the Business Competitiveness of the Generalitat de Catalunya, financial support of MICRO- TEX project (Textile Microencapsulation of Biologically Active Compounds from Natural Sources).
DOI: 10.1016/j.cherd.2019.05.018
ISSN: 0263-8762
WoS: 000475998100031
Scopus: 2-s2.0-85066280952
Институција/група
Tehnološko-metalurški fakultetTY - JOUR AU - Trojanowska, Anna AU - Tsibranska, Iren AU - Dzhonova, Daniela AU - Wroblewska, Michalina AU - Haponska, Monika AU - Jovančić, Petar AU - Marturano, Valentina AU - Tylkowski, Bartosz PY - 2019 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/5915 AB - Sideritis scardica and Sideritis syriaca are considered highly valuable plant materials and their total polyphenols (TP) and total flavonoids (TF) extracts can be employed in nutraceutics and cosmetics. A two-step process was proposed consisting in the ultrasound-assisted extraction (UAE) and concentration of the biologically active compounds via nanofiltration (NF). An extensive comparison between UAE and conventional high-temperature stirring was performed, taking into account the effect of process parameters such as solvent, temperature and ultrasonication. In terms of radical scavenging activity and time optimization, UAE was found more effective, providing – after only 1 h – extraction yields comparable to 20 h of the conventional thermo-mechanical method. The extract was then concentrated by nanofiltration in tangential mode at 20 bar using 300 and 500 Da cut-off Duramem membranes. Permeate and rejection flux was monitored during the filtration process. The lower molecular weight membrane showed higher permeability towards TP and TF and contributed to a more stable flux and lower fouling processes. To predict operational drawbacks, computational fluid dynamic simulations were performed to model the complex rotational flow occurring during membrane filtration. PB - Institution of Chemical Engineers T2 - Chemical Engineering Research and Design T1 - Ultrasound-assisted extraction of biologically active compounds and their successive concentration by using membrane processes EP - 389 SP - 378 VL - 147 DO - 10.1016/j.cherd.2019.05.018 ER -
@article{ author = "Trojanowska, Anna and Tsibranska, Iren and Dzhonova, Daniela and Wroblewska, Michalina and Haponska, Monika and Jovančić, Petar and Marturano, Valentina and Tylkowski, Bartosz", year = "2019", abstract = "Sideritis scardica and Sideritis syriaca are considered highly valuable plant materials and their total polyphenols (TP) and total flavonoids (TF) extracts can be employed in nutraceutics and cosmetics. A two-step process was proposed consisting in the ultrasound-assisted extraction (UAE) and concentration of the biologically active compounds via nanofiltration (NF). An extensive comparison between UAE and conventional high-temperature stirring was performed, taking into account the effect of process parameters such as solvent, temperature and ultrasonication. In terms of radical scavenging activity and time optimization, UAE was found more effective, providing – after only 1 h – extraction yields comparable to 20 h of the conventional thermo-mechanical method. The extract was then concentrated by nanofiltration in tangential mode at 20 bar using 300 and 500 Da cut-off Duramem membranes. Permeate and rejection flux was monitored during the filtration process. The lower molecular weight membrane showed higher permeability towards TP and TF and contributed to a more stable flux and lower fouling processes. To predict operational drawbacks, computational fluid dynamic simulations were performed to model the complex rotational flow occurring during membrane filtration.", publisher = "Institution of Chemical Engineers", journal = "Chemical Engineering Research and Design", title = "Ultrasound-assisted extraction of biologically active compounds and their successive concentration by using membrane processes", pages = "389-378", volume = "147", doi = "10.1016/j.cherd.2019.05.018" }
Trojanowska, A., Tsibranska, I., Dzhonova, D., Wroblewska, M., Haponska, M., Jovančić, P., Marturano, V.,& Tylkowski, B.. (2019). Ultrasound-assisted extraction of biologically active compounds and their successive concentration by using membrane processes. in Chemical Engineering Research and Design Institution of Chemical Engineers., 147, 378-389. https://doi.org/10.1016/j.cherd.2019.05.018
Trojanowska A, Tsibranska I, Dzhonova D, Wroblewska M, Haponska M, Jovančić P, Marturano V, Tylkowski B. Ultrasound-assisted extraction of biologically active compounds and their successive concentration by using membrane processes. in Chemical Engineering Research and Design. 2019;147:378-389. doi:10.1016/j.cherd.2019.05.018 .
Trojanowska, Anna, Tsibranska, Iren, Dzhonova, Daniela, Wroblewska, Michalina, Haponska, Monika, Jovančić, Petar, Marturano, Valentina, Tylkowski, Bartosz, "Ultrasound-assisted extraction of biologically active compounds and their successive concentration by using membrane processes" in Chemical Engineering Research and Design, 147 (2019):378-389, https://doi.org/10.1016/j.cherd.2019.05.018 . .