Micro-kinetic model of fructo-oligosaccharide synthesis for prebiotic products
Само за регистроване кориснике
2023
Аутори
Pravilović, RadoslavaJanković, Tamara
Veljković, Milica
Todić, Branislav
Simović, Milica
Bezbradica, Dejan
Nikačević, Nikola
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
A new micro-kinetic model of the enzyme-catalyzed synthesis of fructo-oligosaccharides (FOS) was developed. A commercial enzyme mixture Pectinex® Ultra SP-L derived from Aspergillus aculeatus was used. A variety of initial enzyme concentrations (1–5 vol%) and sucrose concentrations (400–600 g/L) were experimentally investigated and included in kinetic modeling. Several variations of kinetic mechanisms and corresponding models have been examined. A hybrid genetic algorithm was used to predict the kinetic parameters simultaneously for all experimental data. The best fitting model has been adopted, and with an average error of 13.34%, it describes the experimental data very well. The influence of initial concentrations on the conversion of sucrose and production of FOS is being carefully investigated. It was shown that the initial sucrose concentration significantly affects the highest level of FOS concentration, but the enzyme concentration controls the time at which maximum is reached a...s well as the rate of FOS decomposition.
Кључне речи:
enzymatic reaction / fructo-oligosaccharide / kinetic model / parameter estimationИзвор:
AIChE Journal, 2023, 69, 9, e18122-Издавач:
- John Wiley and Sons Inc.
Финансирање / пројекти:
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200135 (Универзитет у Београду, Технолошко-металуршки факултет) (RS-MESTD-inst-2020-200135)
- PrIntPrEnzy - Prebiotics for functional food and bioactive cosmetics produced in intensified enzymatic processes (RS-ScienceFundRS-Ideje-7750109)
Колекције
Институција/група
Tehnološko-metalurški fakultetTY - JOUR AU - Pravilović, Radoslava AU - Janković, Tamara AU - Veljković, Milica AU - Todić, Branislav AU - Simović, Milica AU - Bezbradica, Dejan AU - Nikačević, Nikola PY - 2023 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/6385 AB - A new micro-kinetic model of the enzyme-catalyzed synthesis of fructo-oligosaccharides (FOS) was developed. A commercial enzyme mixture Pectinex® Ultra SP-L derived from Aspergillus aculeatus was used. A variety of initial enzyme concentrations (1–5 vol%) and sucrose concentrations (400–600 g/L) were experimentally investigated and included in kinetic modeling. Several variations of kinetic mechanisms and corresponding models have been examined. A hybrid genetic algorithm was used to predict the kinetic parameters simultaneously for all experimental data. The best fitting model has been adopted, and with an average error of 13.34%, it describes the experimental data very well. The influence of initial concentrations on the conversion of sucrose and production of FOS is being carefully investigated. It was shown that the initial sucrose concentration significantly affects the highest level of FOS concentration, but the enzyme concentration controls the time at which maximum is reached as well as the rate of FOS decomposition. PB - John Wiley and Sons Inc. T2 - AIChE Journal T1 - Micro-kinetic model of fructo-oligosaccharide synthesis for prebiotic products IS - 9 SP - e18122 VL - 69 DO - 10.1002/aic.18122 ER -
@article{ author = "Pravilović, Radoslava and Janković, Tamara and Veljković, Milica and Todić, Branislav and Simović, Milica and Bezbradica, Dejan and Nikačević, Nikola", year = "2023", abstract = "A new micro-kinetic model of the enzyme-catalyzed synthesis of fructo-oligosaccharides (FOS) was developed. A commercial enzyme mixture Pectinex® Ultra SP-L derived from Aspergillus aculeatus was used. A variety of initial enzyme concentrations (1–5 vol%) and sucrose concentrations (400–600 g/L) were experimentally investigated and included in kinetic modeling. Several variations of kinetic mechanisms and corresponding models have been examined. A hybrid genetic algorithm was used to predict the kinetic parameters simultaneously for all experimental data. The best fitting model has been adopted, and with an average error of 13.34%, it describes the experimental data very well. The influence of initial concentrations on the conversion of sucrose and production of FOS is being carefully investigated. It was shown that the initial sucrose concentration significantly affects the highest level of FOS concentration, but the enzyme concentration controls the time at which maximum is reached as well as the rate of FOS decomposition.", publisher = "John Wiley and Sons Inc.", journal = "AIChE Journal", title = "Micro-kinetic model of fructo-oligosaccharide synthesis for prebiotic products", number = "9", pages = "e18122", volume = "69", doi = "10.1002/aic.18122" }
Pravilović, R., Janković, T., Veljković, M., Todić, B., Simović, M., Bezbradica, D.,& Nikačević, N.. (2023). Micro-kinetic model of fructo-oligosaccharide synthesis for prebiotic products. in AIChE Journal John Wiley and Sons Inc.., 69(9), e18122. https://doi.org/10.1002/aic.18122
Pravilović R, Janković T, Veljković M, Todić B, Simović M, Bezbradica D, Nikačević N. Micro-kinetic model of fructo-oligosaccharide synthesis for prebiotic products. in AIChE Journal. 2023;69(9):e18122. doi:10.1002/aic.18122 .
Pravilović, Radoslava, Janković, Tamara, Veljković, Milica, Todić, Branislav, Simović, Milica, Bezbradica, Dejan, Nikačević, Nikola, "Micro-kinetic model of fructo-oligosaccharide synthesis for prebiotic products" in AIChE Journal, 69, no. 9 (2023):e18122, https://doi.org/10.1002/aic.18122 . .