Antimikrobna aktivnost viskozne tkanine modifikovane hitozanom i nanočesticama Ag

Abstract

Potrebe za medicinskim tekstilom koji poseduje antimikrobna svojstva kontinualno rastu. U poslednje vreme se cine napori da se sinteza nanocestica Ag ostvari upotrebom zelenih redukcionih sredstava, a pre svega biljnih ekstrakta. U ovom radu su nanocestice Ag sintetisane na viskoznoj tkanini modifikovanoj biopolimerom hitozanom sa i bez prisustva umreživaca 1,2,3,4-butantetrakarboksilne kiseline primenom ekstrakta kore nara kao redukcionog sredstva. Uprkos razlici u sadržaju i velicini nanocestica Ag, oba uzorka pokazuju odlicnu antibakterijsku aktivnost prema bakterijamaS. aureusi E. coli, a još bolju antifungalnu aktivnost prema kvascu C. albicans. Pri tome je citotoksicnost ovih uzoraka prema celijama keratinocita ljudske kože niska.

The needs for medical textiles with antimicrobial properties are continually growing. Recently many efforts have been made to synthesize Ag nanoparticles using green reducing agents, in particular plant extracts. In this study Ag nanoparticles were synthesized on viscose rayon fabric modified with biopolymer chitosan with or without crosslinker 1,2,3,4-tetrabutanecarboxylic acid by applying pomegranate peel extract as a reducing agent. Despite the difference in content andsize of Ag nanoparticles both samples showed excellent antibacterial activity against bacteria S. aureus and E. coli and even better against yeast C. albicans. The cytotoxicity of these samples onhuman keratinocyte cellswas low.