Dynamic mechanical properties and in vitro bioactivity of PHBHV/HA nanocomposite
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2007
Authors
Chen, D. Z.Tang, C. Y.

Chan, K. C.

Tsui, C. P.

Yu, Peter H. F.
Leung, Mason C. P.
Uskoković, Petar

Article (Published version)

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Biopolymer composite materials for potential medical applications are of current research interest. In this study, a nanocomposite based on bioresorbable polymer-poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBHV) was prepared by the incorporation of nano-sized hydroxyapatite (nano-HA) using a solution casting method. Homogeneous distribution of nanoparticles in the polymer matrix was validated by the observation of field emission scanning electron microscope (FE-SEM). The dynamic mechanical properties, thermal properties, and bioactivity of the natiocomposite were examined by using varieties of techniques including dynamic mechanical analyser (DMA), differential scanning calorimeter (DSC), thermogravimetric analyzer (TGA), scanning electron microscope coupled with energy dispersive X-ray analysis detector (SEM + EDXA), Fourier transforms infra-red spectrometer (FT-IR) and thin-film X-ray diffractometer (TF-XRD). The results indicated that the storage modulus (E') of PHBHV was conside...rably improved with the introduction of nano-HA. For an instance of examination at I Hz, the PHBHV/HA (100/30) nanocomposite showed an increment of 41.2% at -50 degrees C and 99.1% at 75 degrees C in E' as compared with the polymer matrix. It was also found that higher testing frequencies used induce more elastic-like behavior. With the increase in the amount of nano-HA, both the glass transition temperature (T-g) and the activation energy (Delta E) for the glass transition increased, while the tangent of loss angle (tan delta) decreased due to the hindrance of the nanofillers to the mobility of the polymer segments. The thermal experiments revealed that, when incorporating HA nanoparticles, the decomposition of the polymer matrix was accelerated at the initial stage but postponed thereafter. The addition of nano-HA also resulted in a decrement in the melting enthalpy of PHBHV. The in vitro investigation indicated that the nanocomposite has an improved bioactivity over the conventional one.
Keywords:
polymer-matrix composites (PMCs) / nanostructures / mechanical properties / bioactivitySource:
Composites Science and Technology, 2007, 67, 7-8, 1617-1626Publisher:
- Elsevier Sci Ltd, Oxford
DOI: 10.1016/j.compscitech.2006.07.034
ISSN: 0266-3538
WoS: 000246253200033
Scopus: 2-s2.0-33847793097
Institution/Community
Tehnološko-metalurški fakultetTY - JOUR AU - Chen, D. Z. AU - Tang, C. Y. AU - Chan, K. C. AU - Tsui, C. P. AU - Yu, Peter H. F. AU - Leung, Mason C. P. AU - Uskoković, Petar PY - 2007 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1099 AB - Biopolymer composite materials for potential medical applications are of current research interest. In this study, a nanocomposite based on bioresorbable polymer-poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBHV) was prepared by the incorporation of nano-sized hydroxyapatite (nano-HA) using a solution casting method. Homogeneous distribution of nanoparticles in the polymer matrix was validated by the observation of field emission scanning electron microscope (FE-SEM). The dynamic mechanical properties, thermal properties, and bioactivity of the natiocomposite were examined by using varieties of techniques including dynamic mechanical analyser (DMA), differential scanning calorimeter (DSC), thermogravimetric analyzer (TGA), scanning electron microscope coupled with energy dispersive X-ray analysis detector (SEM + EDXA), Fourier transforms infra-red spectrometer (FT-IR) and thin-film X-ray diffractometer (TF-XRD). The results indicated that the storage modulus (E') of PHBHV was considerably improved with the introduction of nano-HA. For an instance of examination at I Hz, the PHBHV/HA (100/30) nanocomposite showed an increment of 41.2% at -50 degrees C and 99.1% at 75 degrees C in E' as compared with the polymer matrix. It was also found that higher testing frequencies used induce more elastic-like behavior. With the increase in the amount of nano-HA, both the glass transition temperature (T-g) and the activation energy (Delta E) for the glass transition increased, while the tangent of loss angle (tan delta) decreased due to the hindrance of the nanofillers to the mobility of the polymer segments. The thermal experiments revealed that, when incorporating HA nanoparticles, the decomposition of the polymer matrix was accelerated at the initial stage but postponed thereafter. The addition of nano-HA also resulted in a decrement in the melting enthalpy of PHBHV. The in vitro investigation indicated that the nanocomposite has an improved bioactivity over the conventional one. PB - Elsevier Sci Ltd, Oxford T2 - Composites Science and Technology T1 - Dynamic mechanical properties and in vitro bioactivity of PHBHV/HA nanocomposite EP - 1626 IS - 7-8 SP - 1617 VL - 67 DO - 10.1016/j.compscitech.2006.07.034 ER -
@article{ author = "Chen, D. Z. and Tang, C. Y. and Chan, K. C. and Tsui, C. P. and Yu, Peter H. F. and Leung, Mason C. P. and Uskoković, Petar", year = "2007", abstract = "Biopolymer composite materials for potential medical applications are of current research interest. In this study, a nanocomposite based on bioresorbable polymer-poly(3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBHV) was prepared by the incorporation of nano-sized hydroxyapatite (nano-HA) using a solution casting method. Homogeneous distribution of nanoparticles in the polymer matrix was validated by the observation of field emission scanning electron microscope (FE-SEM). The dynamic mechanical properties, thermal properties, and bioactivity of the natiocomposite were examined by using varieties of techniques including dynamic mechanical analyser (DMA), differential scanning calorimeter (DSC), thermogravimetric analyzer (TGA), scanning electron microscope coupled with energy dispersive X-ray analysis detector (SEM + EDXA), Fourier transforms infra-red spectrometer (FT-IR) and thin-film X-ray diffractometer (TF-XRD). The results indicated that the storage modulus (E') of PHBHV was considerably improved with the introduction of nano-HA. For an instance of examination at I Hz, the PHBHV/HA (100/30) nanocomposite showed an increment of 41.2% at -50 degrees C and 99.1% at 75 degrees C in E' as compared with the polymer matrix. It was also found that higher testing frequencies used induce more elastic-like behavior. With the increase in the amount of nano-HA, both the glass transition temperature (T-g) and the activation energy (Delta E) for the glass transition increased, while the tangent of loss angle (tan delta) decreased due to the hindrance of the nanofillers to the mobility of the polymer segments. The thermal experiments revealed that, when incorporating HA nanoparticles, the decomposition of the polymer matrix was accelerated at the initial stage but postponed thereafter. The addition of nano-HA also resulted in a decrement in the melting enthalpy of PHBHV. The in vitro investigation indicated that the nanocomposite has an improved bioactivity over the conventional one.", publisher = "Elsevier Sci Ltd, Oxford", journal = "Composites Science and Technology", title = "Dynamic mechanical properties and in vitro bioactivity of PHBHV/HA nanocomposite", pages = "1626-1617", number = "7-8", volume = "67", doi = "10.1016/j.compscitech.2006.07.034" }
Chen, D. Z., Tang, C. Y., Chan, K. C., Tsui, C. P., Yu, P. H. F., Leung, M. C. P.,& Uskoković, P.. (2007). Dynamic mechanical properties and in vitro bioactivity of PHBHV/HA nanocomposite. in Composites Science and Technology Elsevier Sci Ltd, Oxford., 67(7-8), 1617-1626. https://doi.org/10.1016/j.compscitech.2006.07.034
Chen DZ, Tang CY, Chan KC, Tsui CP, Yu PHF, Leung MCP, Uskoković P. Dynamic mechanical properties and in vitro bioactivity of PHBHV/HA nanocomposite. in Composites Science and Technology. 2007;67(7-8):1617-1626. doi:10.1016/j.compscitech.2006.07.034 .
Chen, D. Z., Tang, C. Y., Chan, K. C., Tsui, C. P., Yu, Peter H. F., Leung, Mason C. P., Uskoković, Petar, "Dynamic mechanical properties and in vitro bioactivity of PHBHV/HA nanocomposite" in Composites Science and Technology, 67, no. 7-8 (2007):1617-1626, https://doi.org/10.1016/j.compscitech.2006.07.034 . .