The qualitative electrochemical determination of clarithromycin and spectroscopic detection of its structural changes at gold electrode
Аутори
Avramov-Ivić, MilkaPetrović, Slobodan
Vonmoos, F.
Mijin, Dušan
Živković, Predrag M.
Drljević, Katica
Чланак у часопису (Објављена верзија)
Метаподаци
Приказ свих података о документуАпстракт
The aim of the present study was the qualitative determination of the pure clarithromycin using a gold electrode in neutral electrolyte by cyclic linear sweep voltammetry. It was shown that in the range of -1.2 V to 1.0 V vs. SCE in 0.05 M NaHCO3, a gold electrode is successfully employed for the qualitative determination of clarithromycin by detection of the reproductive four anodic and one cathodic peaks. After the potentiostatic measurements at the potential values corresponded to current peaks, the bulk electrolyte was analyzed by FTIR spectroscopy to show the changes in molecular structure of clarithromycin. FTIR analysis of the bulk electrolyte after 4 h of holding the potential at -0.61 V vs. SCE (cathodic peak) showed the apparent changes in clarithromycin molecule structure: in the ester bond of the lactone and in ethers and acetal bonds.
Кључне речи:
clarithromycin / qualitative determination / gold electrode / cyclic voltammetry / FTIR spectroscopyИзвор:
Electrochemistry Communications, 2007, 9, 7, 1643-1647Издавач:
- Elsevier Science Inc, New York
Финансирање / пројекти:
- Проучавање синтезе, структуре и активности органских једињења природног и синтетског порекла (RS-142063)
DOI: 10.1016/j.elecom.2007.03.011
ISSN: 1388-2481
WoS: 000248089400042
Scopus: 2-s2.0-34250369288
Институција/група
Tehnološko-metalurški fakultetTY - JOUR AU - Avramov-Ivić, Milka AU - Petrović, Slobodan AU - Vonmoos, F. AU - Mijin, Dušan AU - Živković, Predrag M. AU - Drljević, Katica PY - 2007 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1160 AB - The aim of the present study was the qualitative determination of the pure clarithromycin using a gold electrode in neutral electrolyte by cyclic linear sweep voltammetry. It was shown that in the range of -1.2 V to 1.0 V vs. SCE in 0.05 M NaHCO3, a gold electrode is successfully employed for the qualitative determination of clarithromycin by detection of the reproductive four anodic and one cathodic peaks. After the potentiostatic measurements at the potential values corresponded to current peaks, the bulk electrolyte was analyzed by FTIR spectroscopy to show the changes in molecular structure of clarithromycin. FTIR analysis of the bulk electrolyte after 4 h of holding the potential at -0.61 V vs. SCE (cathodic peak) showed the apparent changes in clarithromycin molecule structure: in the ester bond of the lactone and in ethers and acetal bonds. PB - Elsevier Science Inc, New York T2 - Electrochemistry Communications T1 - The qualitative electrochemical determination of clarithromycin and spectroscopic detection of its structural changes at gold electrode EP - 1647 IS - 7 SP - 1643 VL - 9 DO - 10.1016/j.elecom.2007.03.011 ER -
@article{ author = "Avramov-Ivić, Milka and Petrović, Slobodan and Vonmoos, F. and Mijin, Dušan and Živković, Predrag M. and Drljević, Katica", year = "2007", abstract = "The aim of the present study was the qualitative determination of the pure clarithromycin using a gold electrode in neutral electrolyte by cyclic linear sweep voltammetry. It was shown that in the range of -1.2 V to 1.0 V vs. SCE in 0.05 M NaHCO3, a gold electrode is successfully employed for the qualitative determination of clarithromycin by detection of the reproductive four anodic and one cathodic peaks. After the potentiostatic measurements at the potential values corresponded to current peaks, the bulk electrolyte was analyzed by FTIR spectroscopy to show the changes in molecular structure of clarithromycin. FTIR analysis of the bulk electrolyte after 4 h of holding the potential at -0.61 V vs. SCE (cathodic peak) showed the apparent changes in clarithromycin molecule structure: in the ester bond of the lactone and in ethers and acetal bonds.", publisher = "Elsevier Science Inc, New York", journal = "Electrochemistry Communications", title = "The qualitative electrochemical determination of clarithromycin and spectroscopic detection of its structural changes at gold electrode", pages = "1647-1643", number = "7", volume = "9", doi = "10.1016/j.elecom.2007.03.011" }
Avramov-Ivić, M., Petrović, S., Vonmoos, F., Mijin, D., Živković, P. M.,& Drljević, K.. (2007). The qualitative electrochemical determination of clarithromycin and spectroscopic detection of its structural changes at gold electrode. in Electrochemistry Communications Elsevier Science Inc, New York., 9(7), 1643-1647. https://doi.org/10.1016/j.elecom.2007.03.011
Avramov-Ivić M, Petrović S, Vonmoos F, Mijin D, Živković PM, Drljević K. The qualitative electrochemical determination of clarithromycin and spectroscopic detection of its structural changes at gold electrode. in Electrochemistry Communications. 2007;9(7):1643-1647. doi:10.1016/j.elecom.2007.03.011 .
Avramov-Ivić, Milka, Petrović, Slobodan, Vonmoos, F., Mijin, Dušan, Živković, Predrag M., Drljević, Katica, "The qualitative electrochemical determination of clarithromycin and spectroscopic detection of its structural changes at gold electrode" in Electrochemistry Communications, 9, no. 7 (2007):1643-1647, https://doi.org/10.1016/j.elecom.2007.03.011 . .