Приказ основних података о документу
Ethylene glycol and glycolic acid production by wild-typeEscherichia coli
dc.creator | Lu, Xiyang | |
dc.creator | Yao, Yao | |
dc.creator | Yang, Yang | |
dc.creator | Zhang, Zhongxi | |
dc.creator | Gu, Jinjie | |
dc.creator | Mojović, Ljiljana | |
dc.creator | Knežević-Jugović, Zorica | |
dc.creator | Baganz, Frank | |
dc.creator | Lye, Gary | |
dc.creator | Shi, Jiping | |
dc.creator | Hao, Jian | |
dc.date.accessioned | 2021-03-10T09:33:16Z | |
dc.date.available | 2021-03-10T09:33:16Z | |
dc.date.issued | 2021 | |
dc.identifier.issn | 0885-4513 | |
dc.identifier.uri | http://TechnoRep.tmf.bg.ac.rs/handle/123456789/14 | |
dc.description.abstract | Ethylene glycol and glycolic acid are bulk chemicals with a broad range of applications. The ethylene glycol and glycolic acid biosynthesis pathways have been produced by microorganisms and used as a biological route for their production. Unlike the methods that use xylose or glucose as carbon sources, xylonic acid was used as a carbon source to produce ethylene glycol and glycolic acid in this study. Amounts of 4.2 g/L of ethylene glycol and 0.7 g/L of glycolic acid were produced by a wild-typeEscherichia coliW3110 within 10 H of cultivation with a substrate conversion ratio of 0.5 mol/mol. Furthermore,E. colistrains that produce solely ethylene glycol or glycolic acid were constructed. 10.3 g/L of glycolic acid was produced byE. coli Delta yqhD+aldA, and the achieved conversion ratio was 0.56 mol/mol. Similarly, theE. coli Delta aldA+yqhDproduced 8.0 g/L of ethylene glycol with a conversion ratio of 0.71 mol/mol. Ethylene glycol and glycolic acid production byE. colion xylonic acid as a carbon source provides new information on the biosynthesis pathway of these products and opens a novel way of biomass utilization. | en |
dc.publisher | Wiley, Hoboken | |
dc.relation | National Key R&D Program of China [2017YFE0112700] | |
dc.relation | Royal Society-Newton Advanced Fellowship | |
dc.relation | NAF [\R2\180721] | |
dc.relation | Natural Science Foundation of ShanghaiNatural Science Foundation of Shanghai [19ZR1463600] | |
dc.relation | National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21576279] | |
dc.rights | restrictedAccess | |
dc.source | Biotechnology and Applied Biochemistry | |
dc.subject | E | en |
dc.subject | coli | en |
dc.subject | ethylene glycol | en |
dc.subject | glycolic acid | en |
dc.subject | xylonic acid | en |
dc.subject | xylose | en |
dc.title | Ethylene glycol and glycolic acid production by wild-typeEscherichia coli | en |
dc.type | article | |
dc.rights.license | ARR | |
dc.citation.epage | 755 | |
dc.citation.issue | 4 | |
dc.citation.rank | M23 | |
dc.citation.spage | 744 | |
dc.citation.spage | 755 | |
dc.citation.volume | 68 | |
dc.identifier.doi | 10.1002/bab.1987 | |
dc.identifier.pmid | 32683722 | |
dc.identifier.scopus | 2-s2.0-85088944961 | |
dc.identifier.wos | 000553676700001 | |
dc.type.version | publishedVersion |