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dc.creatorSalcher, Andrea
dc.creatorNikolić, Marija
dc.creatorCasado, Santiago
dc.creatorVelez, Marisela
dc.creatorWeller, Horst
dc.creatorJuarez, Beatriz H.
dc.date.accessioned2021-03-10T11:22:14Z
dc.date.available2021-03-10T11:22:14Z
dc.date.issued2010
dc.identifier.issn0959-9428
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/1687
dc.description.abstractIn this work, CdSe/CdS semiconductor ligand-exchanged nanoparticles have been immobilized on poly-(N-isopropylacrylamide) (pNIPAM)-based microspheres. The size and the shrinkage capacity of the spheres can be tuned by the ratio of NIPAM/styrene (pNIPAM-PS spheres) or NIPAM/BIS (N-N'-methylene-bis-acrylamide) and MA (maleic acid) (pNIPAM-BIS-MA spheres). A ligand-exchange procedure for the transfer of initially organic compatible nanoparticles into aqueous solution using amine-modified or thiol-modified poly(ethylene oxide)s (PEOs) has been carried out prior to their immobilization. We observed that the interaction of the nanoparticles with the pNIPAM-based system depends on the nature of the ligands and the chemical composition of the microspheres. Nanoparticles capped with amine-or mercapto-poly(ethylene oxide) s ligands interact with pNIPAM-PS beads while only amine-capped ones show a clear tendency to interact with pNIPAM containing acid groups which leads to a high nanoparticle coverage. Dynamic light scattering measurements, atomic force microscopy and optical spectroscopy hint that nanoparticles are placed on the surface of pNIPAM-BIS-MA beads while being partially incorporated into pNIPAM-PS network. Cell culture studies demonstrate that the fluorescent composites show non-specific binding to fibroblasts. These features may be very valuable to develop materials for drug delivery and specific targeting of cells combined with the outstanding optical properties of semiconductor nanoparticles as fluorescent labelers.en
dc.publisherRoyal Soc Chemistry, Cambridge
dc.relationEuropean CommissionEuropean CommissionEuropean Commission Joint Research Centre
dc.relationMinisterio de Ciencia e InnovacionInstituto de Salud Carlos IIISpanish Government [CONSOLIDER-INGENIOCSD00C-07-25200]
dc.relationComunidad Autonoma de MadridComunidad de Madrid [S-0505/MAT-0283]
dc.rightsrestrictedAccess
dc.sourceJournal of Materials Chemistry
dc.titleCdSe/CdS nanoparticles immobilized on pNIPAm-based microspheresen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage1374
dc.citation.issue7
dc.citation.other20(7): 1367-1374
dc.citation.rankaM21
dc.citation.spage1367
dc.citation.volume20
dc.identifier.doi10.1039/b917022g
dc.identifier.scopus2-s2.0-75749113670
dc.identifier.wos000274207500018
dc.type.versionpublishedVersion


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Приказ основних података о документу