Retention behavior of some N-(4-phenylsubstituted)-2,3-diphenylpropanamides was investigated on reversed phase thin layer chromatography (RP-C18). Retention constants of investigated compounds were determined in the following solvent systems: water-ethanol, watern-propanol and water-i-propanol. Linear relationships were obtained between retention, RM and volume fraction of organic solvent, ϕ. As a measure of lipophilicity of tested propanamides, Hansch`s lipophilicity parameter, π, were calculated. Chromatography retention constants RM0 were correlated with Hansch`s lipophilicity parameter, and good linear relationships were obtained. These results confirm, that retention constants, (RM0 ), determined in reversed phase thin-layer chromatography (RP-TCL) can be used, as criteria of lipophilicity.
Ključne reči:
Chromatography / Compound / Structure
Izvor:
Journal of Engineering & Processing Management, 2011, 3, 1, 7-15
Izdavač:
University of East Sarajevo, Faculty of Technology
TY - JOUR
AU - Vaštag, Đenđi
AU - Perišić-Janjić, Nada
AU - Apostolov, Suzana
AU - Petrović, Slobodan
PY - 2011
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1764
AB - Retention behavior of some N-(4-phenylsubstituted)-2,3-diphenylpropanamides was investigated on reversed phase thin layer chromatography (RP-C18). Retention constants of investigated compounds were determined in the following solvent systems: water-ethanol, watern-propanol and water-i-propanol. Linear relationships were obtained between retention, RM and volume fraction of organic solvent, ϕ. As a measure of lipophilicity of tested propanamides, Hansch`s lipophilicity parameter, π, were calculated. Chromatography retention constants RM0 were correlated with Hansch`s lipophilicity parameter, and good linear relationships were obtained. These results confirm, that retention constants, (RM0 ), determined in reversed phase thin-layer chromatography (RP-TCL) can be used, as criteria of lipophilicity.
PB - University of East Sarajevo, Faculty of Technology
T2 - Journal of Engineering & Processing Management
T1 - Chromatographic behavior and lipophilicity of n-(4-phenylsubstituted)-2,3-diphenylpropanamides
EP - 15
IS - 1
SP - 7
VL - 3
UR - https://hdl.handle.net/21.15107/rcub_technorep_1764
ER -
@article{
author = "Vaštag, Đenđi and Perišić-Janjić, Nada and Apostolov, Suzana and Petrović, Slobodan",
year = "2011",
abstract = "Retention behavior of some N-(4-phenylsubstituted)-2,3-diphenylpropanamides was investigated on reversed phase thin layer chromatography (RP-C18). Retention constants of investigated compounds were determined in the following solvent systems: water-ethanol, watern-propanol and water-i-propanol. Linear relationships were obtained between retention, RM and volume fraction of organic solvent, ϕ. As a measure of lipophilicity of tested propanamides, Hansch`s lipophilicity parameter, π, were calculated. Chromatography retention constants RM0 were correlated with Hansch`s lipophilicity parameter, and good linear relationships were obtained. These results confirm, that retention constants, (RM0 ), determined in reversed phase thin-layer chromatography (RP-TCL) can be used, as criteria of lipophilicity.",
publisher = "University of East Sarajevo, Faculty of Technology",
journal = "Journal of Engineering & Processing Management",
title = "Chromatographic behavior and lipophilicity of n-(4-phenylsubstituted)-2,3-diphenylpropanamides",
pages = "15-7",
number = "1",
volume = "3",
url = "https://hdl.handle.net/21.15107/rcub_technorep_1764"
}
Vaštag, Đ., Perišić-Janjić, N., Apostolov, S.,& Petrović, S.. (2011). Chromatographic behavior and lipophilicity of n-(4-phenylsubstituted)-2,3-diphenylpropanamides. in Journal of Engineering & Processing Management
University of East Sarajevo, Faculty of Technology., 3(1), 7-15.
https://hdl.handle.net/21.15107/rcub_technorep_1764
Vaštag Đ, Perišić-Janjić N, Apostolov S, Petrović S. Chromatographic behavior and lipophilicity of n-(4-phenylsubstituted)-2,3-diphenylpropanamides. in Journal of Engineering & Processing Management. 2011;3(1):7-15.
https://hdl.handle.net/21.15107/rcub_technorep_1764 .
Vaštag, Đenđi, Perišić-Janjić, Nada, Apostolov, Suzana, Petrović, Slobodan, "Chromatographic behavior and lipophilicity of n-(4-phenylsubstituted)-2,3-diphenylpropanamides" in Journal of Engineering & Processing Management, 3, no. 1 (2011):7-15,
https://hdl.handle.net/21.15107/rcub_technorep_1764 .
