The influence of hydrogenation on the biocompatibility of different hydroxyapatite (HAP) materials was tested. Materials consisted of pure HAP, HAP substituted with manganese (Mn+2) and with magnesium (Mg+2) - all axially pressed and conventionally sintered for 2 h at 1200 degrees C; pure HAP isostatic pressed and sintered by a microwave technique for 15 min at temperature of 1200 degrees C. Biocompatibility was compared by enumeration of the number of osteoblast-like cells to the materials before and after hydrogenation. Obtained results show that the osteoblastic cells demonstrated a higher ability to attach to HAP if its surface was negatively charged. Hydrogenation altered the surface potential; HAP substituted with manganese - HAP(Mn) and with magnesium - HAP(Mg) demonstrated the highest ability to engineer the charge.
Source:
Annual Conference on Functional Materials and Nanotechnologies - FM&NT 2011, 2011, 23
TY - JOUR
AU - Palcevskis, Eriks
AU - Dindune, Antonija
AU - Dekhtyar, Y.
AU - Polyaka, N.
AU - Veljović, Đorđe
AU - Sammons, R. L.
PY - 2011
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1882
AB - The influence of hydrogenation on the biocompatibility of different hydroxyapatite (HAP) materials was tested. Materials consisted of pure HAP, HAP substituted with manganese (Mn+2) and with magnesium (Mg+2) - all axially pressed and conventionally sintered for 2 h at 1200 degrees C; pure HAP isostatic pressed and sintered by a microwave technique for 15 min at temperature of 1200 degrees C. Biocompatibility was compared by enumeration of the number of osteoblast-like cells to the materials before and after hydrogenation. Obtained results show that the osteoblastic cells demonstrated a higher ability to attach to HAP if its surface was negatively charged. Hydrogenation altered the surface potential; HAP substituted with manganese - HAP(Mn) and with magnesium - HAP(Mg) demonstrated the highest ability to engineer the charge.
PB - IOP Publishing Ltd, Bristol
T2 - Annual Conference on Functional Materials and Nanotechnologies - FM&NT 2011
T1 - The Influence of Surface Treatment by Hydrogenation on the Biocompatibility of Different Hydroxyapatite Materials
VL - 23
DO - 10.1088/1757-899X/23/1/012032
ER -
@article{
author = "Palcevskis, Eriks and Dindune, Antonija and Dekhtyar, Y. and Polyaka, N. and Veljović, Đorđe and Sammons, R. L.",
year = "2011",
abstract = "The influence of hydrogenation on the biocompatibility of different hydroxyapatite (HAP) materials was tested. Materials consisted of pure HAP, HAP substituted with manganese (Mn+2) and with magnesium (Mg+2) - all axially pressed and conventionally sintered for 2 h at 1200 degrees C; pure HAP isostatic pressed and sintered by a microwave technique for 15 min at temperature of 1200 degrees C. Biocompatibility was compared by enumeration of the number of osteoblast-like cells to the materials before and after hydrogenation. Obtained results show that the osteoblastic cells demonstrated a higher ability to attach to HAP if its surface was negatively charged. Hydrogenation altered the surface potential; HAP substituted with manganese - HAP(Mn) and with magnesium - HAP(Mg) demonstrated the highest ability to engineer the charge.",
publisher = "IOP Publishing Ltd, Bristol",
journal = "Annual Conference on Functional Materials and Nanotechnologies - FM&NT 2011",
title = "The Influence of Surface Treatment by Hydrogenation on the Biocompatibility of Different Hydroxyapatite Materials",
volume = "23",
doi = "10.1088/1757-899X/23/1/012032"
}
Palcevskis, E., Dindune, A., Dekhtyar, Y., Polyaka, N., Veljović, Đ.,& Sammons, R. L.. (2011). The Influence of Surface Treatment by Hydrogenation on the Biocompatibility of Different Hydroxyapatite Materials. in Annual Conference on Functional Materials and Nanotechnologies - FM&NT 2011
IOP Publishing Ltd, Bristol., 23.
https://doi.org/10.1088/1757-899X/23/1/012032
Palcevskis E, Dindune A, Dekhtyar Y, Polyaka N, Veljović Đ, Sammons RL. The Influence of Surface Treatment by Hydrogenation on the Biocompatibility of Different Hydroxyapatite Materials. in Annual Conference on Functional Materials and Nanotechnologies - FM&NT 2011. 2011;23.
doi:10.1088/1757-899X/23/1/012032 .
Palcevskis, Eriks, Dindune, Antonija, Dekhtyar, Y., Polyaka, N., Veljović, Đorđe, Sammons, R. L., "The Influence of Surface Treatment by Hydrogenation on the Biocompatibility of Different Hydroxyapatite Materials" in Annual Conference on Functional Materials and Nanotechnologies - FM&NT 2011, 23 (2011),
https://doi.org/10.1088/1757-899X/23/1/012032 . .
