Efficiency and Biocompatibility of Antimicrobial Textile Material of Broad Spectrum Activity
Authorized Users Only
2011
Authors
Simović, LjiljanaŠkundrić, Petar
Kostić, Mirjana

Tasić, Goran
Kojić, Zvezdana Z.
Milaković, Branko D.
Medović, Adela
Article (Published version)

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Show full item recordAbstract
the antimicrobial textile material. The material is in the form of plaster wound dressing which is consisting of a nonwoven textile base containing polypropylene (PP)/viscose, a polymer carrier, and an antimicrobial active substance. The polymer carrier is the polysaccharide D-glucosamine (chitosan), and the active antimicrobial substance is antibiotic gentamicin sulfate. The amount of gentamicin sulfate immobilized into the polymer matrix of the polymer carrier was 0.15-0.20 mg/cm(2) or 2.0-2.5% of the mass of the nonwoven textile material. The antimicrobial textile material has been studied in vitro and in vivo conditions through the efficiency of the antimicrobial effects on different kinds of pathogenic microorganisms, as well as the biocompatibility in preclinical research. The results of these experiments indicate that all bioactive textile materials were biocidal in vitro for all pathogenic test organisms. Good biocompatibility, the existence of the correlation between the in vi...tro and in vivo results, concerning efficiency, qualifies these antimicrobial biornaterials for clinical use.
Keywords:
drug delivery system / biocompatibility / biological applications of polymers / polysaccharidesSource:
Journal of Applied Polymer Science, 2011, 120, 3, 1459-1467Publisher:
- Wiley, Hoboken
Funding / projects:
- Ministry of Science of the Republic SerbiaMinistry of Science, Serbia
DOI: 10.1002/app.33235
ISSN: 0021-8995
WoS: 000288142700028
Scopus: 2-s2.0-79551690983
Institution/Community
Tehnološko-metalurški fakultetTY - JOUR AU - Simović, Ljiljana AU - Škundrić, Petar AU - Kostić, Mirjana AU - Tasić, Goran AU - Kojić, Zvezdana Z. AU - Milaković, Branko D. AU - Medović, Adela PY - 2011 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/1948 AB - the antimicrobial textile material. The material is in the form of plaster wound dressing which is consisting of a nonwoven textile base containing polypropylene (PP)/viscose, a polymer carrier, and an antimicrobial active substance. The polymer carrier is the polysaccharide D-glucosamine (chitosan), and the active antimicrobial substance is antibiotic gentamicin sulfate. The amount of gentamicin sulfate immobilized into the polymer matrix of the polymer carrier was 0.15-0.20 mg/cm(2) or 2.0-2.5% of the mass of the nonwoven textile material. The antimicrobial textile material has been studied in vitro and in vivo conditions through the efficiency of the antimicrobial effects on different kinds of pathogenic microorganisms, as well as the biocompatibility in preclinical research. The results of these experiments indicate that all bioactive textile materials were biocidal in vitro for all pathogenic test organisms. Good biocompatibility, the existence of the correlation between the in vitro and in vivo results, concerning efficiency, qualifies these antimicrobial biornaterials for clinical use. PB - Wiley, Hoboken T2 - Journal of Applied Polymer Science T1 - Efficiency and Biocompatibility of Antimicrobial Textile Material of Broad Spectrum Activity EP - 1467 IS - 3 SP - 1459 VL - 120 DO - 10.1002/app.33235 ER -
@article{ author = "Simović, Ljiljana and Škundrić, Petar and Kostić, Mirjana and Tasić, Goran and Kojić, Zvezdana Z. and Milaković, Branko D. and Medović, Adela", year = "2011", abstract = "the antimicrobial textile material. The material is in the form of plaster wound dressing which is consisting of a nonwoven textile base containing polypropylene (PP)/viscose, a polymer carrier, and an antimicrobial active substance. The polymer carrier is the polysaccharide D-glucosamine (chitosan), and the active antimicrobial substance is antibiotic gentamicin sulfate. The amount of gentamicin sulfate immobilized into the polymer matrix of the polymer carrier was 0.15-0.20 mg/cm(2) or 2.0-2.5% of the mass of the nonwoven textile material. The antimicrobial textile material has been studied in vitro and in vivo conditions through the efficiency of the antimicrobial effects on different kinds of pathogenic microorganisms, as well as the biocompatibility in preclinical research. The results of these experiments indicate that all bioactive textile materials were biocidal in vitro for all pathogenic test organisms. Good biocompatibility, the existence of the correlation between the in vitro and in vivo results, concerning efficiency, qualifies these antimicrobial biornaterials for clinical use.", publisher = "Wiley, Hoboken", journal = "Journal of Applied Polymer Science", title = "Efficiency and Biocompatibility of Antimicrobial Textile Material of Broad Spectrum Activity", pages = "1467-1459", number = "3", volume = "120", doi = "10.1002/app.33235" }
Simović, L., Škundrić, P., Kostić, M., Tasić, G., Kojić, Z. Z., Milaković, B. D.,& Medović, A.. (2011). Efficiency and Biocompatibility of Antimicrobial Textile Material of Broad Spectrum Activity. in Journal of Applied Polymer Science Wiley, Hoboken., 120(3), 1459-1467. https://doi.org/10.1002/app.33235
Simović L, Škundrić P, Kostić M, Tasić G, Kojić ZZ, Milaković BD, Medović A. Efficiency and Biocompatibility of Antimicrobial Textile Material of Broad Spectrum Activity. in Journal of Applied Polymer Science. 2011;120(3):1459-1467. doi:10.1002/app.33235 .
Simović, Ljiljana, Škundrić, Petar, Kostić, Mirjana, Tasić, Goran, Kojić, Zvezdana Z., Milaković, Branko D., Medović, Adela, "Efficiency and Biocompatibility of Antimicrobial Textile Material of Broad Spectrum Activity" in Journal of Applied Polymer Science, 120, no. 3 (2011):1459-1467, https://doi.org/10.1002/app.33235 . .