An innovative method was developed for production of alginate hydrogel microbeads incorporated with silver nanoparticles (AgNPs) based on electrochemical synthesis followed by electrostatic extrusion. AgNPs were synthesized galvanostatically at different values of AgNO3 concentration in the initial solution (0.5-3.9 mM), current density (5-50 mA cm(-2)), and implementation time (0.5-10 min). Increase in all of these parameters increased the concentration of AgNPs in alginate solution and was confirmed by TEM analysis and UV-vis spectroscopy. Cyclic voltammetry studies and Fourier transform infrared spectroscopy proved the alginate to be a good capping agent for the electrochemical synthesis of silver nanoparticles, due to coordination bonding between hydroxyl and ether groups, as well as ring oxygen atoms in uronic acid residues of alginate molecules, and Ag nanoparticles. Ag/alginate colloid solution was used for production of uniform hydrogel microbeads (with diameter of 487.75 +/- 1...6.5 mu m) by electrostatic extrusion technique. UV-vis spectroscopy confirmed retention and entrapment of AgNPs in microbeads during the production process. Alginate microbeads incorporated with AgNPs are attractive as biocompatible carriers and/or efficient donors of AgNPs as active components especially for potential biomedical applications, which was demonstrated by the antibacterial activity against Staphylococcus aureus.
TY - JOUR
AU - Jovanović, Zeljka
AU - Stojkovska, Jasmina
AU - Obradović, Bojana
AU - Mišković-Stanković, Vesna
PY - 2012
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2206
AB - An innovative method was developed for production of alginate hydrogel microbeads incorporated with silver nanoparticles (AgNPs) based on electrochemical synthesis followed by electrostatic extrusion. AgNPs were synthesized galvanostatically at different values of AgNO3 concentration in the initial solution (0.5-3.9 mM), current density (5-50 mA cm(-2)), and implementation time (0.5-10 min). Increase in all of these parameters increased the concentration of AgNPs in alginate solution and was confirmed by TEM analysis and UV-vis spectroscopy. Cyclic voltammetry studies and Fourier transform infrared spectroscopy proved the alginate to be a good capping agent for the electrochemical synthesis of silver nanoparticles, due to coordination bonding between hydroxyl and ether groups, as well as ring oxygen atoms in uronic acid residues of alginate molecules, and Ag nanoparticles. Ag/alginate colloid solution was used for production of uniform hydrogel microbeads (with diameter of 487.75 +/- 16.5 mu m) by electrostatic extrusion technique. UV-vis spectroscopy confirmed retention and entrapment of AgNPs in microbeads during the production process. Alginate microbeads incorporated with AgNPs are attractive as biocompatible carriers and/or efficient donors of AgNPs as active components especially for potential biomedical applications, which was demonstrated by the antibacterial activity against Staphylococcus aureus.
PB - Elsevier Science Sa, Lausanne
T2 - Materials Chemistry and Physics
T1 - Alginate hydrogel microbeads incorporated with Ag nanoparticles obtained by electrochemical method
EP - 189
IS - 1
SP - 182
VL - 133
DO - 10.1016/j.matchemphys.2012.01.005
ER -
@article{
author = "Jovanović, Zeljka and Stojkovska, Jasmina and Obradović, Bojana and Mišković-Stanković, Vesna",
year = "2012",
abstract = "An innovative method was developed for production of alginate hydrogel microbeads incorporated with silver nanoparticles (AgNPs) based on electrochemical synthesis followed by electrostatic extrusion. AgNPs were synthesized galvanostatically at different values of AgNO3 concentration in the initial solution (0.5-3.9 mM), current density (5-50 mA cm(-2)), and implementation time (0.5-10 min). Increase in all of these parameters increased the concentration of AgNPs in alginate solution and was confirmed by TEM analysis and UV-vis spectroscopy. Cyclic voltammetry studies and Fourier transform infrared spectroscopy proved the alginate to be a good capping agent for the electrochemical synthesis of silver nanoparticles, due to coordination bonding between hydroxyl and ether groups, as well as ring oxygen atoms in uronic acid residues of alginate molecules, and Ag nanoparticles. Ag/alginate colloid solution was used for production of uniform hydrogel microbeads (with diameter of 487.75 +/- 16.5 mu m) by electrostatic extrusion technique. UV-vis spectroscopy confirmed retention and entrapment of AgNPs in microbeads during the production process. Alginate microbeads incorporated with AgNPs are attractive as biocompatible carriers and/or efficient donors of AgNPs as active components especially for potential biomedical applications, which was demonstrated by the antibacterial activity against Staphylococcus aureus.",
publisher = "Elsevier Science Sa, Lausanne",
journal = "Materials Chemistry and Physics",
title = "Alginate hydrogel microbeads incorporated with Ag nanoparticles obtained by electrochemical method",
pages = "189-182",
number = "1",
volume = "133",
doi = "10.1016/j.matchemphys.2012.01.005"
}
Jovanović, Z., Stojkovska, J., Obradović, B.,& Mišković-Stanković, V.. (2012). Alginate hydrogel microbeads incorporated with Ag nanoparticles obtained by electrochemical method. in Materials Chemistry and Physics
Elsevier Science Sa, Lausanne., 133(1), 182-189.
https://doi.org/10.1016/j.matchemphys.2012.01.005
Jovanović Z, Stojkovska J, Obradović B, Mišković-Stanković V. Alginate hydrogel microbeads incorporated with Ag nanoparticles obtained by electrochemical method. in Materials Chemistry and Physics. 2012;133(1):182-189.
doi:10.1016/j.matchemphys.2012.01.005 .
Jovanović, Zeljka, Stojkovska, Jasmina, Obradović, Bojana, Mišković-Stanković, Vesna, "Alginate hydrogel microbeads incorporated with Ag nanoparticles obtained by electrochemical method" in Materials Chemistry and Physics, 133, no. 1 (2012):182-189,
https://doi.org/10.1016/j.matchemphys.2012.01.005 . .
