Alginate colloid solution containing electrochemically synthesized silver nanoparticles (AgNPs) was investigated regarding the nanoparticle stabilization and possibilities for production of alginate based nanocomposite hydrogels in different forms. AgNPs were shown to continue to grow in alginate solutions for additional 3 days after the synthesis by aggregative mechanism and Ostwald ripening. Thereafter, the colloid solution remains stable for 30 days and could be used alone or in mixtures with aqueous solutions of poly(vinyl alcohol) (PVA) and poly(N-vinyl-2-pyrrolidone) (PVP) while preserving AgNPs as verified by UV-Vis spectroscopy studies. We have optimized techniques for production of Ag/alginate microbeads and Ag/alginate/PVA beads, which were shown to efficiently release AgNPs decreasing the Escherichia coli concentration in suspensions for 99.9% over 24 h. Furthermore, Ag/hydrogel discs based on alginate, PVA and PVP were produced by freezing-thawing technique allowing adjustm...ents of hydrogel composition and mechanical properties as demonstrated in compression studies performed in a biomimetic bioreactor.
Source:
Journal of Materials Science-Materials in Medicine, 2012, 23, 1, 99-107
TY - JOUR
AU - Obradović, Bojana
AU - Stojkovska, Jasmina
AU - Jovanović, Zeljka
AU - Mišković-Stanković, Vesna
PY - 2012
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2221
AB - Alginate colloid solution containing electrochemically synthesized silver nanoparticles (AgNPs) was investigated regarding the nanoparticle stabilization and possibilities for production of alginate based nanocomposite hydrogels in different forms. AgNPs were shown to continue to grow in alginate solutions for additional 3 days after the synthesis by aggregative mechanism and Ostwald ripening. Thereafter, the colloid solution remains stable for 30 days and could be used alone or in mixtures with aqueous solutions of poly(vinyl alcohol) (PVA) and poly(N-vinyl-2-pyrrolidone) (PVP) while preserving AgNPs as verified by UV-Vis spectroscopy studies. We have optimized techniques for production of Ag/alginate microbeads and Ag/alginate/PVA beads, which were shown to efficiently release AgNPs decreasing the Escherichia coli concentration in suspensions for 99.9% over 24 h. Furthermore, Ag/hydrogel discs based on alginate, PVA and PVP were produced by freezing-thawing technique allowing adjustments of hydrogel composition and mechanical properties as demonstrated in compression studies performed in a biomimetic bioreactor.
PB - Springer, Dordrecht
T2 - Journal of Materials Science-Materials in Medicine
T1 - Novel alginate based nanocomposite hydrogels with incorporated silver nanoparticles
EP - 107
IS - 1
SP - 99
VL - 23
DO - 10.1007/s10856-011-4522-1
ER -
@article{
author = "Obradović, Bojana and Stojkovska, Jasmina and Jovanović, Zeljka and Mišković-Stanković, Vesna",
year = "2012",
abstract = "Alginate colloid solution containing electrochemically synthesized silver nanoparticles (AgNPs) was investigated regarding the nanoparticle stabilization and possibilities for production of alginate based nanocomposite hydrogels in different forms. AgNPs were shown to continue to grow in alginate solutions for additional 3 days after the synthesis by aggregative mechanism and Ostwald ripening. Thereafter, the colloid solution remains stable for 30 days and could be used alone or in mixtures with aqueous solutions of poly(vinyl alcohol) (PVA) and poly(N-vinyl-2-pyrrolidone) (PVP) while preserving AgNPs as verified by UV-Vis spectroscopy studies. We have optimized techniques for production of Ag/alginate microbeads and Ag/alginate/PVA beads, which were shown to efficiently release AgNPs decreasing the Escherichia coli concentration in suspensions for 99.9% over 24 h. Furthermore, Ag/hydrogel discs based on alginate, PVA and PVP were produced by freezing-thawing technique allowing adjustments of hydrogel composition and mechanical properties as demonstrated in compression studies performed in a biomimetic bioreactor.",
publisher = "Springer, Dordrecht",
journal = "Journal of Materials Science-Materials in Medicine",
title = "Novel alginate based nanocomposite hydrogels with incorporated silver nanoparticles",
pages = "107-99",
number = "1",
volume = "23",
doi = "10.1007/s10856-011-4522-1"
}
Obradović, B., Stojkovska, J., Jovanović, Z.,& Mišković-Stanković, V.. (2012). Novel alginate based nanocomposite hydrogels with incorporated silver nanoparticles. in Journal of Materials Science-Materials in Medicine
Springer, Dordrecht., 23(1), 99-107.
https://doi.org/10.1007/s10856-011-4522-1
Obradović B, Stojkovska J, Jovanović Z, Mišković-Stanković V. Novel alginate based nanocomposite hydrogels with incorporated silver nanoparticles. in Journal of Materials Science-Materials in Medicine. 2012;23(1):99-107.
doi:10.1007/s10856-011-4522-1 .
Obradović, Bojana, Stojkovska, Jasmina, Jovanović, Zeljka, Mišković-Stanković, Vesna, "Novel alginate based nanocomposite hydrogels with incorporated silver nanoparticles" in Journal of Materials Science-Materials in Medicine, 23, no. 1 (2012):99-107,
https://doi.org/10.1007/s10856-011-4522-1 . .
