Effect of the pH of artificial saliva on ion release from commercially pure titanium

Abstract

Due to their excellent characteristics, such as chemical inertness, mechanical resistance, low Young's modulus, high corrosion resistance, and outstanding biocompatibility, titanium and its alloys are the most used metallic materials for biomedical applications. In dental practice, these materials have demonstrated success as biomedical devices which are used for repairing and replacing failed hard tissue. However, the oral cavity is constantly subjected to the changes in the pH value changes and such an environment is strongly corrosive for titanium dental implants. The objective of this study was to examine ion release from commercially pure titanium (cpTi) in artificial saliva with different pH values (4.0, 5.5 and 7.5). The concentrations of released titanium ions were determined after 1, 3 and 6 weeks using Inductively Coupled Plasma - Mass Spectrometry. The results indicate that the ion release from commercially pure titanium in the artificial saliva is dependent both on the pH of artificial saliva and duration of immersion.

Titan i njegove legure su najčešće korišćeni metalni materijali za biomedicinsku primenu zbog njihovih odličnih karakteristika, kao što su hemijska inertnost, mehanička otpornost, nizak Jungov modul, visoka otpornost na koroziju i izvanredna biokompatibilnost. U stomatološkoj praksi, titan i njegove legure su pokazali uspeh kao biomedicinski uređaji, koji se koriste za popravku ili zamenu oštećenih čvrstih tkiva. Međutim, usna duplja je stalno izložena promenama pH vrednosti i takva sredina je izuzetno koroziona za dentalne implantate izrađene od titana. Cilj ovog rada je bio da se ispita otpuštanje jona iz komercijalno čistog titana (cpTi) u veštačkoj pljuvačci različite pH vrednosti (4.0, 5.5 i 7.5). Koncentracije otpuštenih jona titana su određene posle 1, 3 i 6 nedelja korišćenjem induktivno spregnute plazme sa masenom spektrometrijom (ICP-MS). Rezultati pokazuju da otpuštanje jona iz komercijalno čistog titana zavisi i od pH vrednosti veštačke pljuvačke i od dužine trajanja potapanja.