Function of the microbiota
Abstract
The gut microbiota of humans is complex but stable in composition and function. Metabolic conversions performed by the members of the microbiota yield both beneficial and hazardous compounds, and have a systematic impact on human health. Comparative studies have shown that the microbiota of patients, suffering from a number of diseases, is in dysbiosis, which is characterized by a distinct composition. Compositional differences have also been noted between members of geographically distant healthy populations. To be able to identify which compositional changes promote compromised health, it is of interest to identify members of the microbiota that perform essential metabolic transformations. This review provides an insight into the microbial contribution to the metabolism of carbohydrates, proteins and bile acids, and focuses on the link between diversity and function.
Keywords:
Microbiota / Microbiome / Dysbiosis / Carbohydrate metabolism / Protein metabolism / Bile acid metabolismSource:
Best Practice & Research Clinical Gastroenterology, 2013, 27, 1, 5-16Publisher:
- Elsevier Sci Ltd, Oxford
DOI: 10.1016/j.bpg.2013.03.006
ISSN: 1521-6918
PubMed: 23768548
WoS: 000322352400002
Scopus: 2-s2.0-84879110534
Institution/Community
Tehnološko-metalurški fakultetTY - JOUR AU - Rajilić-Stojanović, Mirjana PY - 2013 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2419 AB - The gut microbiota of humans is complex but stable in composition and function. Metabolic conversions performed by the members of the microbiota yield both beneficial and hazardous compounds, and have a systematic impact on human health. Comparative studies have shown that the microbiota of patients, suffering from a number of diseases, is in dysbiosis, which is characterized by a distinct composition. Compositional differences have also been noted between members of geographically distant healthy populations. To be able to identify which compositional changes promote compromised health, it is of interest to identify members of the microbiota that perform essential metabolic transformations. This review provides an insight into the microbial contribution to the metabolism of carbohydrates, proteins and bile acids, and focuses on the link between diversity and function. PB - Elsevier Sci Ltd, Oxford T2 - Best Practice & Research Clinical Gastroenterology T1 - Function of the microbiota EP - 16 IS - 1 SP - 5 VL - 27 DO - 10.1016/j.bpg.2013.03.006 ER -
@article{ author = "Rajilić-Stojanović, Mirjana", year = "2013", abstract = "The gut microbiota of humans is complex but stable in composition and function. Metabolic conversions performed by the members of the microbiota yield both beneficial and hazardous compounds, and have a systematic impact on human health. Comparative studies have shown that the microbiota of patients, suffering from a number of diseases, is in dysbiosis, which is characterized by a distinct composition. Compositional differences have also been noted between members of geographically distant healthy populations. To be able to identify which compositional changes promote compromised health, it is of interest to identify members of the microbiota that perform essential metabolic transformations. This review provides an insight into the microbial contribution to the metabolism of carbohydrates, proteins and bile acids, and focuses on the link between diversity and function.", publisher = "Elsevier Sci Ltd, Oxford", journal = "Best Practice & Research Clinical Gastroenterology", title = "Function of the microbiota", pages = "16-5", number = "1", volume = "27", doi = "10.1016/j.bpg.2013.03.006" }
Rajilić-Stojanović, M.. (2013). Function of the microbiota. in Best Practice & Research Clinical Gastroenterology Elsevier Sci Ltd, Oxford., 27(1), 5-16. https://doi.org/10.1016/j.bpg.2013.03.006
Rajilić-Stojanović M. Function of the microbiota. in Best Practice & Research Clinical Gastroenterology. 2013;27(1):5-16. doi:10.1016/j.bpg.2013.03.006 .
Rajilić-Stojanović, Mirjana, "Function of the microbiota" in Best Practice & Research Clinical Gastroenterology, 27, no. 1 (2013):5-16, https://doi.org/10.1016/j.bpg.2013.03.006 . .