The antibacterial activity of natural zeolite (NZ) containing 2.03 wt.% of Cu2+ (CuNZ), 5.07 of Ag+ (AgNZ) or 8.50 of benzalkonium ion (BCNZ) were tested against clinical isolates of Acinetobacter baumannii belonging to European clone I and II. Isolate from clone II was more sensitive to CuNZ and AgNZ with minimum bactericidal concentration (MBC) 125 and 31.2 mg L-1, respectively than isolate from clone I with MBC of 250 mg L-1 for both CuNZ and AgNZ. Isolate from clone I was more sensitive to BCNZ with MBC 250 mg L-1 than isolate from clone II with MBC 500 mg L-1. The minimum inhibitory concentration (MIC) values were the same or slightly lower than the MBC values. The antibacterial activity of CuNZ, AgNZ and BCNZ against the A. baumannii European clone I and II was due to the activity of cations loaded onto NZ while not to the NZ used as support material. The antibacterial activity of CuNZ, AgNZ and BCNZ opens a possibility of future clinical investigations and its application.
TY - JOUR
AU - Hrenović, Jasna
AU - Milenković, Jelena
AU - Goić-Barisić, Ivana
AU - Rajić, Nevenka
PY - 2013
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2488
AB - The antibacterial activity of natural zeolite (NZ) containing 2.03 wt.% of Cu2+ (CuNZ), 5.07 of Ag+ (AgNZ) or 8.50 of benzalkonium ion (BCNZ) were tested against clinical isolates of Acinetobacter baumannii belonging to European clone I and II. Isolate from clone II was more sensitive to CuNZ and AgNZ with minimum bactericidal concentration (MBC) 125 and 31.2 mg L-1, respectively than isolate from clone I with MBC of 250 mg L-1 for both CuNZ and AgNZ. Isolate from clone I was more sensitive to BCNZ with MBC 250 mg L-1 than isolate from clone II with MBC 500 mg L-1. The minimum inhibitory concentration (MIC) values were the same or slightly lower than the MBC values. The antibacterial activity of CuNZ, AgNZ and BCNZ against the A. baumannii European clone I and II was due to the activity of cations loaded onto NZ while not to the NZ used as support material. The antibacterial activity of CuNZ, AgNZ and BCNZ opens a possibility of future clinical investigations and its application.
PB - Elsevier, Amsterdam
T2 - Microporous and Mesoporous Materials
T1 - Antibacterial activity of modified natural clinoptilolite against clinical isolates of Acinetobacter baumannii
EP - 152
SP - 148
VL - 169
DO - 10.1016/j.micromeso.2012.10.026
ER -
@article{
author = "Hrenović, Jasna and Milenković, Jelena and Goić-Barisić, Ivana and Rajić, Nevenka",
year = "2013",
abstract = "The antibacterial activity of natural zeolite (NZ) containing 2.03 wt.% of Cu2+ (CuNZ), 5.07 of Ag+ (AgNZ) or 8.50 of benzalkonium ion (BCNZ) were tested against clinical isolates of Acinetobacter baumannii belonging to European clone I and II. Isolate from clone II was more sensitive to CuNZ and AgNZ with minimum bactericidal concentration (MBC) 125 and 31.2 mg L-1, respectively than isolate from clone I with MBC of 250 mg L-1 for both CuNZ and AgNZ. Isolate from clone I was more sensitive to BCNZ with MBC 250 mg L-1 than isolate from clone II with MBC 500 mg L-1. The minimum inhibitory concentration (MIC) values were the same or slightly lower than the MBC values. The antibacterial activity of CuNZ, AgNZ and BCNZ against the A. baumannii European clone I and II was due to the activity of cations loaded onto NZ while not to the NZ used as support material. The antibacterial activity of CuNZ, AgNZ and BCNZ opens a possibility of future clinical investigations and its application.",
publisher = "Elsevier, Amsterdam",
journal = "Microporous and Mesoporous Materials",
title = "Antibacterial activity of modified natural clinoptilolite against clinical isolates of Acinetobacter baumannii",
pages = "152-148",
volume = "169",
doi = "10.1016/j.micromeso.2012.10.026"
}
Hrenović, J., Milenković, J., Goić-Barisić, I.,& Rajić, N.. (2013). Antibacterial activity of modified natural clinoptilolite against clinical isolates of Acinetobacter baumannii. in Microporous and Mesoporous Materials
Elsevier, Amsterdam., 169, 148-152.
https://doi.org/10.1016/j.micromeso.2012.10.026
Hrenović J, Milenković J, Goić-Barisić I, Rajić N. Antibacterial activity of modified natural clinoptilolite against clinical isolates of Acinetobacter baumannii. in Microporous and Mesoporous Materials. 2013;169:148-152.
doi:10.1016/j.micromeso.2012.10.026 .
Hrenović, Jasna, Milenković, Jelena, Goić-Barisić, Ivana, Rajić, Nevenka, "Antibacterial activity of modified natural clinoptilolite against clinical isolates of Acinetobacter baumannii" in Microporous and Mesoporous Materials, 169 (2013):148-152,
https://doi.org/10.1016/j.micromeso.2012.10.026 . .
