Through this study, an attempt has been made to evaluate the solubility of thymol in supercritical carbon dioxide as well to investigate a prospect of its impregnation on cotton gauze on laboratory scale. Solubility of thymol in supercritical carbon dioxide was determined at temperatures of 35 degrees C, 40 degrees C and 50 degrees C, and pressures ranging from 7.8 to 25 MPa (CO2 density range 335.89-849.60 kg/m(3)) using a static method. The solubility data were correlated using semi-empirical equations introduced by Chrastil, Adachi and Lu and del Valle and Aguilera. Taking into account obtained results, temperature of 35 degrees C and pressure of 15.5 MPa were selected as operating conditions for the impregnation process. Impregnation of cotton gauze with thymol was performed in a cell using carbon dioxide as a solvent. Kinetics of the process was determined and modeled. Masses of thymol on cotton gauzes after 2 h and 24 h of impregnation were 11% and 19.6%, respectively. FT-IR anal...ysis confirmed the presence of thymol on the surface of the cotton fibers. The impregnated gauze provided strong antimicrobial activity against tested strains of Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Enterococcus faecalis and Candida albicans.
TY - JOUR
AU - Milovanović, Stoja
AU - Stamenić, Marko
AU - Marković, Darka
AU - Radetić, Maja
AU - Žižović, Irena
PY - 2013
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2497
AB - Through this study, an attempt has been made to evaluate the solubility of thymol in supercritical carbon dioxide as well to investigate a prospect of its impregnation on cotton gauze on laboratory scale. Solubility of thymol in supercritical carbon dioxide was determined at temperatures of 35 degrees C, 40 degrees C and 50 degrees C, and pressures ranging from 7.8 to 25 MPa (CO2 density range 335.89-849.60 kg/m(3)) using a static method. The solubility data were correlated using semi-empirical equations introduced by Chrastil, Adachi and Lu and del Valle and Aguilera. Taking into account obtained results, temperature of 35 degrees C and pressure of 15.5 MPa were selected as operating conditions for the impregnation process. Impregnation of cotton gauze with thymol was performed in a cell using carbon dioxide as a solvent. Kinetics of the process was determined and modeled. Masses of thymol on cotton gauzes after 2 h and 24 h of impregnation were 11% and 19.6%, respectively. FT-IR analysis confirmed the presence of thymol on the surface of the cotton fibers. The impregnated gauze provided strong antimicrobial activity against tested strains of Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Enterococcus faecalis and Candida albicans.
PB - Elsevier Science Bv, Amsterdam
T2 - Journal of Supercritical Fluids
T1 - Solubility of thymol in supercritical carbon dioxide and its impregnation on cotton gauze
EP - 181
SP - 173
VL - 84
DO - 10.1016/j.supflu.2013.10.003
ER -
@article{
author = "Milovanović, Stoja and Stamenić, Marko and Marković, Darka and Radetić, Maja and Žižović, Irena",
year = "2013",
abstract = "Through this study, an attempt has been made to evaluate the solubility of thymol in supercritical carbon dioxide as well to investigate a prospect of its impregnation on cotton gauze on laboratory scale. Solubility of thymol in supercritical carbon dioxide was determined at temperatures of 35 degrees C, 40 degrees C and 50 degrees C, and pressures ranging from 7.8 to 25 MPa (CO2 density range 335.89-849.60 kg/m(3)) using a static method. The solubility data were correlated using semi-empirical equations introduced by Chrastil, Adachi and Lu and del Valle and Aguilera. Taking into account obtained results, temperature of 35 degrees C and pressure of 15.5 MPa were selected as operating conditions for the impregnation process. Impregnation of cotton gauze with thymol was performed in a cell using carbon dioxide as a solvent. Kinetics of the process was determined and modeled. Masses of thymol on cotton gauzes after 2 h and 24 h of impregnation were 11% and 19.6%, respectively. FT-IR analysis confirmed the presence of thymol on the surface of the cotton fibers. The impregnated gauze provided strong antimicrobial activity against tested strains of Escherichia coli, Staphylococcus aureus, Bacillus subtilis, Enterococcus faecalis and Candida albicans.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Solubility of thymol in supercritical carbon dioxide and its impregnation on cotton gauze",
pages = "181-173",
volume = "84",
doi = "10.1016/j.supflu.2013.10.003"
}
Milovanović, S., Stamenić, M., Marković, D., Radetić, M.,& Žižović, I.. (2013). Solubility of thymol in supercritical carbon dioxide and its impregnation on cotton gauze. in Journal of Supercritical Fluids
Elsevier Science Bv, Amsterdam., 84, 173-181.
https://doi.org/10.1016/j.supflu.2013.10.003
Milovanović S, Stamenić M, Marković D, Radetić M, Žižović I. Solubility of thymol in supercritical carbon dioxide and its impregnation on cotton gauze. in Journal of Supercritical Fluids. 2013;84:173-181.
doi:10.1016/j.supflu.2013.10.003 .
Milovanović, Stoja, Stamenić, Marko, Marković, Darka, Radetić, Maja, Žižović, Irena, "Solubility of thymol in supercritical carbon dioxide and its impregnation on cotton gauze" in Journal of Supercritical Fluids, 84 (2013):173-181,
https://doi.org/10.1016/j.supflu.2013.10.003 . .
