Oscillatory flow chemical reactors
Hemijski reaktori sa oscilirajućim tokom fluida
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Global market competition, increase in energy and other production costs, demands for high quality products and reduction of waste are forcing pharmaceutical, fine chemicals and biochemical industries, to search for radical solutions. One of the most effective ways to improve the overall production (cost reduction and better control of reactions) is a transition from batch to continuous processes. However, the reactions of interests for the mentioned industry sectors are often slow, thus continuous tubular reactors would be impractically long for flow regimes which provide sufficient heat and mass transfer and narrow residence time distribution. The oscillatory flow reactors (OFR) are newer type of tube reactors which can offer solution by providing continuous operation with approximately plug flow pattern, low shear stress rates and enhanced mass and heat transfer. These benefits are the result of very good mixing in OFR achieved by vortex generation. OFR consists of cylindrical tube ...containing equally spaced orifice baffles. Fluid oscillations are superimposed on a net (laminar) flow. Eddies are generated when oscillating fluid collides with baffles and passes through orifices. Generation and propagation of vortices create uniform mixing in each reactor cavity (between baffles), providing an overall flow pattern which is close to plug flow. Oscillations can be created by direct action of a piston or a diaphragm on fluid (or alternatively on baffles). This article provides an overview of oscillatory flow reactor technology, its operating principles and basic design and scale-up characteristics. Further, the article reviews the key research findings in heat and mass transfer, shear stress, residence time distribution in OFR, presenting their advantages over the conventional reactors. Finally, relevant process intensification examples from pharmaceutical, polymer and biofuels industries are presented.
Ekonomski i ekološki pritisci, kao što su globalna konkurencija, povećanje energetskih i drugih troškova proizvodnje, zahtevi za visokim kvalitetom proizvoda i smanjenje otpada, primoravaju farmaceutsku, finu hemijsku i biohemijsku industriju na radikalne promene u proizvodnji. Jedan od efikasnih načina za sveobuhvatno poboljšanje proizvodnje (smanjenje troškova i bolju kontrolu reakcije) je prelazak sa tradicionalno šaržnih procesa na kontinualne. Međutim, reakcije od interesa za pomenute industrijske sektore su često spore, pa bi kontinualni cevni reaktori trebalo da budu nepraktično velikih dužina za režime strujanja koji obezbeđuju zadovoljavajuće prenose toplote i mase i uske raspodele vremena zadržavanja. Reaktori sa oscilirajućim tokom fluida (ROT) nude rešenje jer obezbeđuju kontinualni rad, strujanje blisko klipnom, visoke prenose mase i toplote, a pri tom se mogu koristiti male brzine strujanja, te su reaktori prihvatljivih dužina za spore reakcije. Ove pozitivne karakteristi...ke se ostvaruju zbog jako dobrog mešanja u reaktoru, usled stvaranja vrtloga pri sudaru generisanog talasa fluida sa internim pregradama. Osim navedenih prednosti u ROT se obezbeđuju i niži smicajni naponi (za isti unos energije) u odnosu na reaktore sa mehaničkim mešalicama, što je značajno za aplikacije u biohemijskom i biomedicinskom inženjerstvu. U ovom preglednom radu je predstavljen princip rada ovih reaktora, različite konstrukcije i osnovni kriterijumi za projektovanje. Prikazani su reprezentativni rezultati istraživanja, koji jasno potvrđuju prednosti ovih uređaja u odnosu na konvencionalne i navedeni su primeri intenzifikacije procesa primenom ROT u različitim industrijskim sektorima, kao što su farmaceutski, polimerni, biogoriva, prerada otpadnih voda i dr.
Keywords:
Process intensification / Oscillatory flow reactors / Batch to continuous processes / Oscillatory flow mixing / intenzifikacija procesa / reaktori sa oscilirajućim tokom / šaržni ka kontinualnim procesima / mešanje pomoću oscilacija fluidaSource:
Hemijska industrija, 2014, 68, 3, 363-379Publisher:
- Association of Chemical Engineers of Serbia
Funding / projects:
- The development of efficient chemical-engineering processes based on the transport phenomena research and process intensification principles (RS-172022)
- Develooment and utilization of novel and traditional technologies in production of competitive food products with added valued for national and global market - CREATING WEALTH FROM THE WEALTH OF SERBIA (RS-46001)
- The development of efficient chemical-engineering processes based on the transport phenomena research and process intensification principles (RS-172022)
DOI: 10.2298/HEMIND130419062S
ISSN: 0367-598X
WoS: 000339707000011
Scopus: 2-s2.0-84904092574
Institution/Community
Tehnološko-metalurški fakultetTY - JOUR AU - Slavnić, Danijela AU - Bugarski, Branko AU - Nikačević, Nikola PY - 2014 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2629 AB - Global market competition, increase in energy and other production costs, demands for high quality products and reduction of waste are forcing pharmaceutical, fine chemicals and biochemical industries, to search for radical solutions. One of the most effective ways to improve the overall production (cost reduction and better control of reactions) is a transition from batch to continuous processes. However, the reactions of interests for the mentioned industry sectors are often slow, thus continuous tubular reactors would be impractically long for flow regimes which provide sufficient heat and mass transfer and narrow residence time distribution. The oscillatory flow reactors (OFR) are newer type of tube reactors which can offer solution by providing continuous operation with approximately plug flow pattern, low shear stress rates and enhanced mass and heat transfer. These benefits are the result of very good mixing in OFR achieved by vortex generation. OFR consists of cylindrical tube containing equally spaced orifice baffles. Fluid oscillations are superimposed on a net (laminar) flow. Eddies are generated when oscillating fluid collides with baffles and passes through orifices. Generation and propagation of vortices create uniform mixing in each reactor cavity (between baffles), providing an overall flow pattern which is close to plug flow. Oscillations can be created by direct action of a piston or a diaphragm on fluid (or alternatively on baffles). This article provides an overview of oscillatory flow reactor technology, its operating principles and basic design and scale-up characteristics. Further, the article reviews the key research findings in heat and mass transfer, shear stress, residence time distribution in OFR, presenting their advantages over the conventional reactors. Finally, relevant process intensification examples from pharmaceutical, polymer and biofuels industries are presented. AB - Ekonomski i ekološki pritisci, kao što su globalna konkurencija, povećanje energetskih i drugih troškova proizvodnje, zahtevi za visokim kvalitetom proizvoda i smanjenje otpada, primoravaju farmaceutsku, finu hemijsku i biohemijsku industriju na radikalne promene u proizvodnji. Jedan od efikasnih načina za sveobuhvatno poboljšanje proizvodnje (smanjenje troškova i bolju kontrolu reakcije) je prelazak sa tradicionalno šaržnih procesa na kontinualne. Međutim, reakcije od interesa za pomenute industrijske sektore su često spore, pa bi kontinualni cevni reaktori trebalo da budu nepraktično velikih dužina za režime strujanja koji obezbeđuju zadovoljavajuće prenose toplote i mase i uske raspodele vremena zadržavanja. Reaktori sa oscilirajućim tokom fluida (ROT) nude rešenje jer obezbeđuju kontinualni rad, strujanje blisko klipnom, visoke prenose mase i toplote, a pri tom se mogu koristiti male brzine strujanja, te su reaktori prihvatljivih dužina za spore reakcije. Ove pozitivne karakteristike se ostvaruju zbog jako dobrog mešanja u reaktoru, usled stvaranja vrtloga pri sudaru generisanog talasa fluida sa internim pregradama. Osim navedenih prednosti u ROT se obezbeđuju i niži smicajni naponi (za isti unos energije) u odnosu na reaktore sa mehaničkim mešalicama, što je značajno za aplikacije u biohemijskom i biomedicinskom inženjerstvu. U ovom preglednom radu je predstavljen princip rada ovih reaktora, različite konstrukcije i osnovni kriterijumi za projektovanje. Prikazani su reprezentativni rezultati istraživanja, koji jasno potvrđuju prednosti ovih uređaja u odnosu na konvencionalne i navedeni su primeri intenzifikacije procesa primenom ROT u različitim industrijskim sektorima, kao što su farmaceutski, polimerni, biogoriva, prerada otpadnih voda i dr. PB - Association of Chemical Engineers of Serbia T2 - Hemijska industrija T1 - Oscillatory flow chemical reactors T1 - Hemijski reaktori sa oscilirajućim tokom fluida EP - 379 IS - 3 SP - 363 VL - 68 DO - 10.2298/HEMIND130419062S ER -
@article{ author = "Slavnić, Danijela and Bugarski, Branko and Nikačević, Nikola", year = "2014", abstract = "Global market competition, increase in energy and other production costs, demands for high quality products and reduction of waste are forcing pharmaceutical, fine chemicals and biochemical industries, to search for radical solutions. One of the most effective ways to improve the overall production (cost reduction and better control of reactions) is a transition from batch to continuous processes. However, the reactions of interests for the mentioned industry sectors are often slow, thus continuous tubular reactors would be impractically long for flow regimes which provide sufficient heat and mass transfer and narrow residence time distribution. The oscillatory flow reactors (OFR) are newer type of tube reactors which can offer solution by providing continuous operation with approximately plug flow pattern, low shear stress rates and enhanced mass and heat transfer. These benefits are the result of very good mixing in OFR achieved by vortex generation. OFR consists of cylindrical tube containing equally spaced orifice baffles. Fluid oscillations are superimposed on a net (laminar) flow. Eddies are generated when oscillating fluid collides with baffles and passes through orifices. Generation and propagation of vortices create uniform mixing in each reactor cavity (between baffles), providing an overall flow pattern which is close to plug flow. Oscillations can be created by direct action of a piston or a diaphragm on fluid (or alternatively on baffles). This article provides an overview of oscillatory flow reactor technology, its operating principles and basic design and scale-up characteristics. Further, the article reviews the key research findings in heat and mass transfer, shear stress, residence time distribution in OFR, presenting their advantages over the conventional reactors. Finally, relevant process intensification examples from pharmaceutical, polymer and biofuels industries are presented., Ekonomski i ekološki pritisci, kao što su globalna konkurencija, povećanje energetskih i drugih troškova proizvodnje, zahtevi za visokim kvalitetom proizvoda i smanjenje otpada, primoravaju farmaceutsku, finu hemijsku i biohemijsku industriju na radikalne promene u proizvodnji. Jedan od efikasnih načina za sveobuhvatno poboljšanje proizvodnje (smanjenje troškova i bolju kontrolu reakcije) je prelazak sa tradicionalno šaržnih procesa na kontinualne. Međutim, reakcije od interesa za pomenute industrijske sektore su često spore, pa bi kontinualni cevni reaktori trebalo da budu nepraktično velikih dužina za režime strujanja koji obezbeđuju zadovoljavajuće prenose toplote i mase i uske raspodele vremena zadržavanja. Reaktori sa oscilirajućim tokom fluida (ROT) nude rešenje jer obezbeđuju kontinualni rad, strujanje blisko klipnom, visoke prenose mase i toplote, a pri tom se mogu koristiti male brzine strujanja, te su reaktori prihvatljivih dužina za spore reakcije. Ove pozitivne karakteristike se ostvaruju zbog jako dobrog mešanja u reaktoru, usled stvaranja vrtloga pri sudaru generisanog talasa fluida sa internim pregradama. Osim navedenih prednosti u ROT se obezbeđuju i niži smicajni naponi (za isti unos energije) u odnosu na reaktore sa mehaničkim mešalicama, što je značajno za aplikacije u biohemijskom i biomedicinskom inženjerstvu. U ovom preglednom radu je predstavljen princip rada ovih reaktora, različite konstrukcije i osnovni kriterijumi za projektovanje. Prikazani su reprezentativni rezultati istraživanja, koji jasno potvrđuju prednosti ovih uređaja u odnosu na konvencionalne i navedeni su primeri intenzifikacije procesa primenom ROT u različitim industrijskim sektorima, kao što su farmaceutski, polimerni, biogoriva, prerada otpadnih voda i dr.", publisher = "Association of Chemical Engineers of Serbia", journal = "Hemijska industrija", title = "Oscillatory flow chemical reactors, Hemijski reaktori sa oscilirajućim tokom fluida", pages = "379-363", number = "3", volume = "68", doi = "10.2298/HEMIND130419062S" }
Slavnić, D., Bugarski, B.,& Nikačević, N.. (2014). Oscillatory flow chemical reactors. in Hemijska industrija Association of Chemical Engineers of Serbia., 68(3), 363-379. https://doi.org/10.2298/HEMIND130419062S
Slavnić D, Bugarski B, Nikačević N. Oscillatory flow chemical reactors. in Hemijska industrija. 2014;68(3):363-379. doi:10.2298/HEMIND130419062S .
Slavnić, Danijela, Bugarski, Branko, Nikačević, Nikola, "Oscillatory flow chemical reactors" in Hemijska industrija, 68, no. 3 (2014):363-379, https://doi.org/10.2298/HEMIND130419062S . .