Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives

Šekularac, Gavrilo; Nikolić, Jasmina; Petrović, Predrag; Bugarski, Branko; Durović, Boban; Drmanić, Saša

doi:10.2298/JSC140709084S

2014

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Durović, Boban
Drmanić, Saša

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Abstract

The isatin derivatives, Schiff bases, were synthesized by the reaction of isatin and various substituted primary amines and characterized by several spectroscopic methods. Investigation of the antimicrobial activity of the synthesized compounds was performed by the agar dilution method, against different strains of bacteria and one fungus. The antioxidative activity of the synthesized compounds was also determined. Some of the compounds showed significant activity against the selected strains of microorganisms and antioxidative activity.

Keywords:

isatin derivatives / Schiff bases / antimicrobial activity / antioxidative activity

Source:
Journal of the Serbian Chemical Society, 2014, 79, 11, 1347-1354

Publisher:

Srpsko hemijsko društvo, Beograd

Funding / projects:

DOI: 10.2298/JSC140709084S

ISSN: 0352-5139

WoS: 000346879000002

Scopus: 2-s2.0-84986882191

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	13
	11

URI

http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2700

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Institution/Community

Tehnološko-metalurški fakultet

TY  - JOUR
AU  - Šekularac, Gavrilo
AU  - Nikolić, Jasmina
AU  - Petrović, Predrag
AU  - Bugarski, Branko
AU  - Durović, Boban
AU  - Drmanić, Saša
PY  - 2014
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2700
AB  - The isatin derivatives, Schiff bases, were synthesized by the reaction of isatin and various substituted primary amines and characterized by several spectroscopic methods. Investigation of the antimicrobial activity of the synthesized compounds was performed by the agar dilution method, against different strains of bacteria and one fungus. The antioxidative activity of the synthesized compounds was also determined. Some of the compounds showed significant activity against the selected strains of microorganisms and antioxidative activity.
PB  - Srpsko hemijsko društvo, Beograd
T2  - Journal of the Serbian Chemical Society
T1  - Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives
EP  - 1354
IS  - 11
SP  - 1347
VL  - 79
DO  - 10.2298/JSC140709084S
ER  -

@article{
author = "Šekularac, Gavrilo and Nikolić, Jasmina and Petrović, Predrag and Bugarski, Branko and Durović, Boban and Drmanić, Saša",
year = "2014",
abstract = "The isatin derivatives, Schiff bases, were synthesized by the reaction of isatin and various substituted primary amines and characterized by several spectroscopic methods. Investigation of the antimicrobial activity of the synthesized compounds was performed by the agar dilution method, against different strains of bacteria and one fungus. The antioxidative activity of the synthesized compounds was also determined. Some of the compounds showed significant activity against the selected strains of microorganisms and antioxidative activity.",
publisher = "Srpsko hemijsko društvo, Beograd",
journal = "Journal of the Serbian Chemical Society",
title = "Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives",
pages = "1354-1347",
number = "11",
volume = "79",
doi = "10.2298/JSC140709084S"
}

Šekularac, G., Nikolić, J., Petrović, P., Bugarski, B., Durović, B.,& Drmanić, S.. (2014). Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives. in Journal of the Serbian Chemical Society
Srpsko hemijsko društvo, Beograd., 79(11), 1347-1354.
https://doi.org/10.2298/JSC140709084S

Šekularac G, Nikolić J, Petrović P, Bugarski B, Durović B, Drmanić S. Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives. in Journal of the Serbian Chemical Society. 2014;79(11):1347-1354.
doi:10.2298/JSC140709084S .

Šekularac, Gavrilo, Nikolić, Jasmina, Petrović, Predrag, Bugarski, Branko, Durović, Boban, Drmanić, Saša, "Synthesis, antimicrobial and antioxidative activity of some new isatin derivatives" in Journal of the Serbian Chemical Society, 79, no. 11 (2014):1347-1354,
https://doi.org/10.2298/JSC140709084S . .