Приказ основних података о документу

dc.creatorScanlan, Pauline D.
dc.creatorStensvold, Christen R.
dc.creatorRajilić-Stojanović, Mirjana
dc.creatorHeilig, Hans G. H. J.
dc.creatorde Vos, Willem M.
dc.creatorO'Toole, Paul W.
dc.creatorCotter, Paul D.
dc.date.accessioned2021-03-10T12:29:08Z
dc.date.available2021-03-10T12:29:08Z
dc.date.issued2014
dc.identifier.issn0168-6496
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/2741
dc.description.abstractTo date, the majority of research into the human gut microbiota has focused on the bacterial fraction of the community. Inevitably, this has resulted in a poor understanding of the diversity and functionality of other intestinal microorganisms in the human gut. One such nonbacterial member is the microbial eukaryote Blastocystis, which has been implicated in the aetiology of a range of different intestinal and extra-intestinal diseases. However, prevalence data from different studies are conflicting, and crucially, there is limited information on its incidence and diversity in healthy individuals. Here, we survey the prevalence, genetic diversity and temporal stability of Blastocystis in a group of healthy adults (n=105) using a sensitive PCR assay. Blastocystis was present in 56% of our sample set, which is much higher than previously reported from an industrialised county (Ireland). Moreover, a diversity of different subtypes (species) were detected, and Blastocystis was present in a subset of individuals sampled over a period of time between 6 and 10years, indicating that it is capable of long-term host colonisation. These results show that Blastocystis is a common and diverse member of the healthy gut microbiota, thereby extending our knowledge of the microbial ecology of the healthy human intestine.en
dc.publisherOxford Univ Press, Oxford
dc.relationIntra-European Marie Curie Research FellowshipEuropean Union (EU)
dc.rightsopenAccess
dc.sourceFEMS Microbiology Ecology
dc.subjectgut microbiotaen
dc.subjectBlastocystisen
dc.subjectintestinal diseaseen
dc.titleThe microbial eukaryote Blastocystis is a prevalent and diverse member of the healthy human gut microbiotaen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage330
dc.citation.issue1
dc.citation.other90(1): 326-330
dc.citation.rankM21
dc.citation.spage326
dc.citation.volume90
dc.identifier.doi10.1111/1574-6941.12396
dc.identifier.fulltexthttp://TechnoRep.tmf.bg.ac.rs/bitstream/id/9161/90-1-326.pdf
dc.identifier.pmid25077936
dc.identifier.scopus2-s2.0-84907868514
dc.identifier.wos000343809700026
dc.type.versionpublishedVersion


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Приказ основних података о документу