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dc.creatorMatić, Ivana
dc.creatorGrujić, Svetlana
dc.creatorJauković, Zorica D.
dc.creatorLaušević, Mila
dc.date.accessioned2021-03-10T12:29:45Z
dc.date.available2021-03-10T12:29:45Z
dc.date.issued2014
dc.identifier.issn0021-9673
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/2751
dc.description.abstractIn this paper, development and optimization of new LC-MS method for determination of twenty selected hormones, human/animal and plant sterols in river sediments were described. Sediment samples were prepared using ultrasonic extraction and clean up with silica gel/anhydrous sodium sulphate cartridge. Extracts were analyzed by liquid chromatography-linear ion trap-tandem mass spectrometry, with atmospheric pressure chemical ionization. The optimized extraction parameters were extraction solvent (methanol), weight of the sediment (2g) and time of ultrasonic extraction (3x 10 min). Successful chromatographic separation of hormones (estriol and estrone, 17 alpha- and 17 beta-estradiol) and four human/animal sterols (epicoprostanol, coprostanol, alpha-cholestanol and beta-cholestanol) that have identical fragmentation reactions was achieved. The developed and optimized method provided high recoveries (73-118%), low limits of detection (0.8-18 ng g(-1)) and quantification (2.5-60 ng g(-1)) with the RSDs generally lower than 20%. Applicability of the developed method was confirmed by analysis of six river sediment samples. A widespread occurrence of human/animal and plant sterols was found. The only detected hormone was mestranol in just one sediment sample.en
dc.publisherElsevier, Amsterdam
dc.relationinfo:eu-repo/grantAgreement/MESTD/Basic Research (BR or ON)/172007/RS//
dc.rightsrestrictedAccess
dc.sourceJournal of Chromatography A
dc.subjectSteroidsen
dc.subjectHormonesen
dc.subjectSterolsen
dc.subjectSedimentsen
dc.subjectLC-MSen
dc.titleTrace analysis of selected hormones and sterols in river sediments by liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometryen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage127
dc.citation.other1364: 117-127
dc.citation.rankaM21
dc.citation.spage117
dc.citation.volume1364
dc.identifier.doi10.1016/j.chroma.2014.08.061
dc.identifier.pmid25182857
dc.identifier.rcubconv_4558
dc.identifier.scopus2-s2.0-84922022414
dc.identifier.wos000343359200014
dc.type.versionpublishedVersion


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