Cytotoxicity studies of Ag/alginate nanocomposite hydrogels in 2D and 3D cultures

dc.creator	Zvicer, Jovana
dc.creator	Samardžić, M.
dc.creator	Mišković-Stanković, Vesna
dc.creator	Obradović, Bojana
dc.date.accessioned	2021-03-10T12:38:01Z
dc.date.available	2021-03-10T12:38:01Z
dc.date.issued	2015
dc.identifier.isbn	978-146737983-0
dc.identifier.uri	http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2880
dc.description.abstract	Alginate nanocomposite hydrogels with incorporated electrochemically synthesized silver nanoparticles were investigated regarding cytotoxicity in vitro. Direct contact test of Ag/alginate discs was applied in 2D monolayer cultures of bovine calf chondrocytes while a 3D culture of bovine articular cartilage explants pressed by the discs was established in a biomimetic bioreactor with dynamic compression in the physiological regime (10 % strain, 0.84 Hz frequency, 1 h on / 1 h off). Moderate cytotoxicity was observed in 2D cell cultures as opposed to findings in 3D explant cultures, which were not affected by the Ag/alginate discs despite the compression.	en
dc.publisher	15th IEEE International Conference on Bioinformatics and Bioengineering, BIBE 2015
dc.rights	restrictedAccess
dc.source	2015 IEEE 15th International Conference on Bioinformatics and Bioengineering, BIBE 2015
dc.title	Cytotoxicity studies of Ag/alginate nanocomposite hydrogels in 2D and 3D cultures	en
dc.type	conferenceObject
dc.rights.license	ARR
dc.identifier.doi	10.1109/BIBE.2015.7367664
dc.identifier.pmid
dc.identifier.scopus	2-s2.0-84962875856
dc.type.version	publishedVersion

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