Various modeling approaches have been applied to describe structural changes of the erythrocyte constituents under osmotic stress. The constituents: (1) the lipid bilayer, (2) the actin spectrin cortex, (3) the trans-membrane protein band 3, (4) the intracellular hemoglobin contribute to the relaxation phenomenon. Cells response includes the successive sub-bioprocesses: (1) erythrocyte swelling, (2) lifetime of the lipid structural integrity and the rearrangements of trans-membrane protein band 3, (3) the reversible hemolytic hole formation and hemoglobin release to surrounding solution. Herein, an attempt is made to discuss and connect various modeling approaches on various time scales which have been proposed in the literature in order to shed further light to this complex phenomenon which induces the erythrocyte to ghost phase transition. The results indicate that the erythrocyte swelling rate represents the key control factor for the structural ordering of the cell parts which indu...ces anomalous nature of energy dissipation.
TY - JOUR
AU - Pajić-Lijaković, Ivana
PY - 2015
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/2980
AB - Various modeling approaches have been applied to describe structural changes of the erythrocyte constituents under osmotic stress. The constituents: (1) the lipid bilayer, (2) the actin spectrin cortex, (3) the trans-membrane protein band 3, (4) the intracellular hemoglobin contribute to the relaxation phenomenon. Cells response includes the successive sub-bioprocesses: (1) erythrocyte swelling, (2) lifetime of the lipid structural integrity and the rearrangements of trans-membrane protein band 3, (3) the reversible hemolytic hole formation and hemoglobin release to surrounding solution. Herein, an attempt is made to discuss and connect various modeling approaches on various time scales which have been proposed in the literature in order to shed further light to this complex phenomenon which induces the erythrocyte to ghost phase transition. The results indicate that the erythrocyte swelling rate represents the key control factor for the structural ordering of the cell parts which induces anomalous nature of energy dissipation.
PB - Pergamon-Elsevier Science Ltd, Oxford
T2 - Progress in Biophysics & Molecular Biology
T1 - Erythrocytes under osmotic stress - modeling considerations
EP - 124
IS - 1
SP - 113
VL - 117
DO - 10.1016/j.pbiomolbio.2014.11.003
ER -
@article{
author = "Pajić-Lijaković, Ivana",
year = "2015",
abstract = "Various modeling approaches have been applied to describe structural changes of the erythrocyte constituents under osmotic stress. The constituents: (1) the lipid bilayer, (2) the actin spectrin cortex, (3) the trans-membrane protein band 3, (4) the intracellular hemoglobin contribute to the relaxation phenomenon. Cells response includes the successive sub-bioprocesses: (1) erythrocyte swelling, (2) lifetime of the lipid structural integrity and the rearrangements of trans-membrane protein band 3, (3) the reversible hemolytic hole formation and hemoglobin release to surrounding solution. Herein, an attempt is made to discuss and connect various modeling approaches on various time scales which have been proposed in the literature in order to shed further light to this complex phenomenon which induces the erythrocyte to ghost phase transition. The results indicate that the erythrocyte swelling rate represents the key control factor for the structural ordering of the cell parts which induces anomalous nature of energy dissipation.",
publisher = "Pergamon-Elsevier Science Ltd, Oxford",
journal = "Progress in Biophysics & Molecular Biology",
title = "Erythrocytes under osmotic stress - modeling considerations",
pages = "124-113",
number = "1",
volume = "117",
doi = "10.1016/j.pbiomolbio.2014.11.003"
}
Pajić-Lijaković, I.. (2015). Erythrocytes under osmotic stress - modeling considerations. in Progress in Biophysics & Molecular Biology
Pergamon-Elsevier Science Ltd, Oxford., 117(1), 113-124.
https://doi.org/10.1016/j.pbiomolbio.2014.11.003
Pajić-Lijaković I. Erythrocytes under osmotic stress - modeling considerations. in Progress in Biophysics & Molecular Biology. 2015;117(1):113-124.
doi:10.1016/j.pbiomolbio.2014.11.003 .
Pajić-Lijaković, Ivana, "Erythrocytes under osmotic stress - modeling considerations" in Progress in Biophysics & Molecular Biology, 117, no. 1 (2015):113-124,
https://doi.org/10.1016/j.pbiomolbio.2014.11.003 . .
