Приказ основних података о документу

dc.creatorPajić-Lijaković, Ivana
dc.date.accessioned2021-03-10T12:44:29Z
dc.date.available2021-03-10T12:44:29Z
dc.date.issued2015
dc.identifier.issn0079-6107
dc.identifier.urihttp://TechnoRep.tmf.bg.ac.rs/handle/123456789/2980
dc.description.abstractVarious modeling approaches have been applied to describe structural changes of the erythrocyte constituents under osmotic stress. The constituents: (1) the lipid bilayer, (2) the actin spectrin cortex, (3) the trans-membrane protein band 3, (4) the intracellular hemoglobin contribute to the relaxation phenomenon. Cells response includes the successive sub-bioprocesses: (1) erythrocyte swelling, (2) lifetime of the lipid structural integrity and the rearrangements of trans-membrane protein band 3, (3) the reversible hemolytic hole formation and hemoglobin release to surrounding solution. Herein, an attempt is made to discuss and connect various modeling approaches on various time scales which have been proposed in the literature in order to shed further light to this complex phenomenon which induces the erythrocyte to ghost phase transition. The results indicate that the erythrocyte swelling rate represents the key control factor for the structural ordering of the cell parts which induces anomalous nature of energy dissipation.en
dc.publisherPergamon-Elsevier Science Ltd, Oxford
dc.relationinfo:eu-repo/grantAgreement/MESTD/Integrated and Interdisciplinary Research (IIR or III)/46001/RS//
dc.rightsrestrictedAccess
dc.sourceProgress in Biophysics & Molecular Biology
dc.subjectErythrocyte relaxationen
dc.subjectBand 3 rearrangementen
dc.subjectReversible hemolytic hole formationen
dc.subjectActin cortex-lipid bilayer couplingen
dc.subjectOsmotic stressen
dc.subjectMathematical modelingen
dc.titleErythrocytes under osmotic stress - modeling considerationsen
dc.typearticle
dc.rights.licenseARR
dc.citation.epage124
dc.citation.issue1
dc.citation.other117(1): 113-124
dc.citation.rankM22
dc.citation.spage113
dc.citation.volume117
dc.identifier.doi10.1016/j.pbiomolbio.2014.11.003
dc.identifier.pmid25433233
dc.identifier.scopus2-s2.0-84924798724
dc.identifier.wos000351807100012
dc.type.versionpublishedVersion


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Приказ основних података о документу