2-Hydroxyethyl Metahcrylate/Gelatin based Superporous Hydrogels for Tissue Regeneration
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2016
Authors
Tomić, SimonidaBabić, Marija
Vuković, Jovana
Perišić, Marija D.
Filipović, Vuk
Davidović, Slađana
Filipović, Jovanka M.
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In this study, superporous hydrogels were synthesized by free radical polymerization of 2-hydroxyethyl methacrylate without and in the presence of gelatin. Highly porous hydrogel structures were obtained by two different techniques: using a gas blowing agent, sodium bicarbonate, and a cryogenic treatment followed by freeze-drying. After the gel synthesis, gelatin molecules were covalently immobilised onto PHEMA via glytaraldehyde activation. All samples were characterized for morphological, mechanical, swelling and antibacterial properties. The results obtained show that samples with gelatin show better properties in comparison with PHEMA samples, which make these materials highly attractive for developing hydrogel scaffolds for tissue regeneration.
Keywords:
2-Hydroxyethyl methacrylate / Hydrogel / Tissue regenerationSource:
VIII International Conference on Times of Polymers and Composites: From Aerospace to Nanotechnology, 2016, 1736, 4949668-Publisher:
- Amer Inst Physics, Melville
Funding / projects:
- Synthesis and characterization of novel functional polymers and polymeric nanocomposites (RS-172062)
DOI: 10.1063/1.4949668
ISBN: 978-073541390-0
ISSN: 0094-243X
WoS: 000387931100093
Scopus: 2-s2.0-84984550802
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Tehnološko-metalurški fakultetTY - CONF AU - Tomić, Simonida AU - Babić, Marija AU - Vuković, Jovana AU - Perišić, Marija D. AU - Filipović, Vuk AU - Davidović, Slađana AU - Filipović, Jovanka M. PY - 2016 UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3296 AB - In this study, superporous hydrogels were synthesized by free radical polymerization of 2-hydroxyethyl methacrylate without and in the presence of gelatin. Highly porous hydrogel structures were obtained by two different techniques: using a gas blowing agent, sodium bicarbonate, and a cryogenic treatment followed by freeze-drying. After the gel synthesis, gelatin molecules were covalently immobilised onto PHEMA via glytaraldehyde activation. All samples were characterized for morphological, mechanical, swelling and antibacterial properties. The results obtained show that samples with gelatin show better properties in comparison with PHEMA samples, which make these materials highly attractive for developing hydrogel scaffolds for tissue regeneration. PB - Amer Inst Physics, Melville C3 - VIII International Conference on Times of Polymers and Composites: From Aerospace to Nanotechnology T1 - 2-Hydroxyethyl Metahcrylate/Gelatin based Superporous Hydrogels for Tissue Regeneration SP - 4949668 VL - 1736 DO - 10.1063/1.4949668 ER -
@conference{ author = "Tomić, Simonida and Babić, Marija and Vuković, Jovana and Perišić, Marija D. and Filipović, Vuk and Davidović, Slađana and Filipović, Jovanka M.", year = "2016", abstract = "In this study, superporous hydrogels were synthesized by free radical polymerization of 2-hydroxyethyl methacrylate without and in the presence of gelatin. Highly porous hydrogel structures were obtained by two different techniques: using a gas blowing agent, sodium bicarbonate, and a cryogenic treatment followed by freeze-drying. After the gel synthesis, gelatin molecules were covalently immobilised onto PHEMA via glytaraldehyde activation. All samples were characterized for morphological, mechanical, swelling and antibacterial properties. The results obtained show that samples with gelatin show better properties in comparison with PHEMA samples, which make these materials highly attractive for developing hydrogel scaffolds for tissue regeneration.", publisher = "Amer Inst Physics, Melville", journal = "VIII International Conference on Times of Polymers and Composites: From Aerospace to Nanotechnology", title = "2-Hydroxyethyl Metahcrylate/Gelatin based Superporous Hydrogels for Tissue Regeneration", pages = "4949668", volume = "1736", doi = "10.1063/1.4949668" }
Tomić, S., Babić, M., Vuković, J., Perišić, M. D., Filipović, V., Davidović, S.,& Filipović, J. M.. (2016). 2-Hydroxyethyl Metahcrylate/Gelatin based Superporous Hydrogels for Tissue Regeneration. in VIII International Conference on Times of Polymers and Composites: From Aerospace to Nanotechnology Amer Inst Physics, Melville., 1736, 4949668. https://doi.org/10.1063/1.4949668
Tomić S, Babić M, Vuković J, Perišić MD, Filipović V, Davidović S, Filipović JM. 2-Hydroxyethyl Metahcrylate/Gelatin based Superporous Hydrogels for Tissue Regeneration. in VIII International Conference on Times of Polymers and Composites: From Aerospace to Nanotechnology. 2016;1736:4949668. doi:10.1063/1.4949668 .
Tomić, Simonida, Babić, Marija, Vuković, Jovana, Perišić, Marija D., Filipović, Vuk, Davidović, Slađana, Filipović, Jovanka M., "2-Hydroxyethyl Metahcrylate/Gelatin based Superporous Hydrogels for Tissue Regeneration" in VIII International Conference on Times of Polymers and Composites: From Aerospace to Nanotechnology, 1736 (2016):4949668, https://doi.org/10.1063/1.4949668 . .