Silver/poly(vinyl alcohol), Ag/PVA, and silver/poly(vinyl alcohol)/graphene, Ag/PVA/Gr, composite hydrogel discs were produced by freezing/thawing, followed by electrochemical reduction of Ag+ ions inside respective matrices, at constant voltage in specially designed electrochemical cell. Raman, FT-IR and FE-SEM characterized interactions between PVA, graphene and silver nanoparticles. Ag/PVA and Ag/PVA/Gr discs classified as non-cytotoxic towards peripheral blood mononuclear cells (PBMC) according to MTT cytotoxicity test, while exhibiting antibacterial activity against Staphylococcus aureus and Escherichia coli. The slow silver release and high remaining silver content of similar to 67-68 wt % after 28 day immersion in simulated body fluid confirmed that both composites can preserve their sterility overtime.
Keywords:
Polymer-matrix composites (PMCs) / Chemical properties / Electron microscopy / Non-destructive testing
Source:
Composites Part B-Engineering, 2016, 104, 26-34
Publisher:
Elsevier Sci Ltd, Oxford
Funding / projects:
Basic Science Research Program through National Research Foundation of Korea (NRF) - Ministry of Education, Science and Technology [2016R1A2B4016034]
TY - JOUR
AU - Abudabbus, M. M.
AU - Jevremović, Ivana
AU - Janković, Ana
AU - Perić-Grujić, Aleksandra
AU - Matić, I.
AU - Vukašinović-Sekulić, Maja
AU - Hui, David
AU - Rhee, Kyong Yop
AU - Mišković-Stanković, Vesna
PY - 2016
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3333
AB - Silver/poly(vinyl alcohol), Ag/PVA, and silver/poly(vinyl alcohol)/graphene, Ag/PVA/Gr, composite hydrogel discs were produced by freezing/thawing, followed by electrochemical reduction of Ag+ ions inside respective matrices, at constant voltage in specially designed electrochemical cell. Raman, FT-IR and FE-SEM characterized interactions between PVA, graphene and silver nanoparticles. Ag/PVA and Ag/PVA/Gr discs classified as non-cytotoxic towards peripheral blood mononuclear cells (PBMC) according to MTT cytotoxicity test, while exhibiting antibacterial activity against Staphylococcus aureus and Escherichia coli. The slow silver release and high remaining silver content of similar to 67-68 wt % after 28 day immersion in simulated body fluid confirmed that both composites can preserve their sterility overtime.
PB - Elsevier Sci Ltd, Oxford
T2 - Composites Part B-Engineering
T1 - Biological activity of electrochemically synthesized silver doped polyvinyl alcohol/graphene composite hydrogel discs for biomedical applications
EP - 34
SP - 26
VL - 104
DO - 10.1016/j.compositesb.2016.08.024
ER -
@article{
author = "Abudabbus, M. M. and Jevremović, Ivana and Janković, Ana and Perić-Grujić, Aleksandra and Matić, I. and Vukašinović-Sekulić, Maja and Hui, David and Rhee, Kyong Yop and Mišković-Stanković, Vesna",
year = "2016",
abstract = "Silver/poly(vinyl alcohol), Ag/PVA, and silver/poly(vinyl alcohol)/graphene, Ag/PVA/Gr, composite hydrogel discs were produced by freezing/thawing, followed by electrochemical reduction of Ag+ ions inside respective matrices, at constant voltage in specially designed electrochemical cell. Raman, FT-IR and FE-SEM characterized interactions between PVA, graphene and silver nanoparticles. Ag/PVA and Ag/PVA/Gr discs classified as non-cytotoxic towards peripheral blood mononuclear cells (PBMC) according to MTT cytotoxicity test, while exhibiting antibacterial activity against Staphylococcus aureus and Escherichia coli. The slow silver release and high remaining silver content of similar to 67-68 wt % after 28 day immersion in simulated body fluid confirmed that both composites can preserve their sterility overtime.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Composites Part B-Engineering",
title = "Biological activity of electrochemically synthesized silver doped polyvinyl alcohol/graphene composite hydrogel discs for biomedical applications",
pages = "34-26",
volume = "104",
doi = "10.1016/j.compositesb.2016.08.024"
}
Abudabbus, M. M., Jevremović, I., Janković, A., Perić-Grujić, A., Matić, I., Vukašinović-Sekulić, M., Hui, D., Rhee, K. Y.,& Mišković-Stanković, V.. (2016). Biological activity of electrochemically synthesized silver doped polyvinyl alcohol/graphene composite hydrogel discs for biomedical applications. in Composites Part B-Engineering
Elsevier Sci Ltd, Oxford., 104, 26-34.
https://doi.org/10.1016/j.compositesb.2016.08.024
Abudabbus MM, Jevremović I, Janković A, Perić-Grujić A, Matić I, Vukašinović-Sekulić M, Hui D, Rhee KY, Mišković-Stanković V. Biological activity of electrochemically synthesized silver doped polyvinyl alcohol/graphene composite hydrogel discs for biomedical applications. in Composites Part B-Engineering. 2016;104:26-34.
doi:10.1016/j.compositesb.2016.08.024 .
Abudabbus, M. M., Jevremović, Ivana, Janković, Ana, Perić-Grujić, Aleksandra, Matić, I., Vukašinović-Sekulić, Maja, Hui, David, Rhee, Kyong Yop, Mišković-Stanković, Vesna, "Biological activity of electrochemically synthesized silver doped polyvinyl alcohol/graphene composite hydrogel discs for biomedical applications" in Composites Part B-Engineering, 104 (2016):26-34,
https://doi.org/10.1016/j.compositesb.2016.08.024 . .
