The chemical composition, antimicrobial and antioxidant activity of Thymus praecox extracts obtained by fractional supercritical fluid extraction (SFE) with carbon dioxide were investigated. Properties of supercritical extracts and extracts obtained by Soxhiet extraction were compared. The chemical composition of extracts was determined using GC-FID and GC-MS analytical methods. The antimicrobial activity of extracts was evaluated against 16 pathogenic microorganisms using microdilution method. Antioxidant potential of extracts to neutralize DPPH radicals was also investigated. Investigated supercritical extracts showed better antimicrobial activity than commercial antibiotics (streptomycin and ampicillin) and commercial fungicides (bifonazol and ketoconazole) against all tested strains. For bacteria MIC and MBC were 38-200 mu g/m1 and 75-300 mu g/ml, respectively, while for fungi MIC and MFC were 17-150 mu g/ml and 35-300 mu g/ml, respectively.
TY - JOUR
AU - Petrović, Nada V.
AU - Petrović, Slobodan S.
AU - Džamić, Ana M.
AU - Ćirić, Ana D.
AU - Ristić, Mihailo S.
AU - Milovanović, Stoja
AU - Petrović, Slobodan
PY - 2016
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3394
AB - The chemical composition, antimicrobial and antioxidant activity of Thymus praecox extracts obtained by fractional supercritical fluid extraction (SFE) with carbon dioxide were investigated. Properties of supercritical extracts and extracts obtained by Soxhiet extraction were compared. The chemical composition of extracts was determined using GC-FID and GC-MS analytical methods. The antimicrobial activity of extracts was evaluated against 16 pathogenic microorganisms using microdilution method. Antioxidant potential of extracts to neutralize DPPH radicals was also investigated. Investigated supercritical extracts showed better antimicrobial activity than commercial antibiotics (streptomycin and ampicillin) and commercial fungicides (bifonazol and ketoconazole) against all tested strains. For bacteria MIC and MBC were 38-200 mu g/m1 and 75-300 mu g/ml, respectively, while for fungi MIC and MFC were 17-150 mu g/ml and 35-300 mu g/ml, respectively.
PB - Elsevier Science Bv, Amsterdam
T2 - Journal of Supercritical Fluids
T1 - Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts
EP - 125
SP - 117
VL - 110
DO - 10.1016/j.supflu.2016.01.001
ER -
@article{
author = "Petrović, Nada V. and Petrović, Slobodan S. and Džamić, Ana M. and Ćirić, Ana D. and Ristić, Mihailo S. and Milovanović, Stoja and Petrović, Slobodan",
year = "2016",
abstract = "The chemical composition, antimicrobial and antioxidant activity of Thymus praecox extracts obtained by fractional supercritical fluid extraction (SFE) with carbon dioxide were investigated. Properties of supercritical extracts and extracts obtained by Soxhiet extraction were compared. The chemical composition of extracts was determined using GC-FID and GC-MS analytical methods. The antimicrobial activity of extracts was evaluated against 16 pathogenic microorganisms using microdilution method. Antioxidant potential of extracts to neutralize DPPH radicals was also investigated. Investigated supercritical extracts showed better antimicrobial activity than commercial antibiotics (streptomycin and ampicillin) and commercial fungicides (bifonazol and ketoconazole) against all tested strains. For bacteria MIC and MBC were 38-200 mu g/m1 and 75-300 mu g/ml, respectively, while for fungi MIC and MFC were 17-150 mu g/ml and 35-300 mu g/ml, respectively.",
publisher = "Elsevier Science Bv, Amsterdam",
journal = "Journal of Supercritical Fluids",
title = "Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts",
pages = "125-117",
volume = "110",
doi = "10.1016/j.supflu.2016.01.001"
}
Petrović, N. V., Petrović, S. S., Džamić, A. M., Ćirić, A. D., Ristić, M. S., Milovanović, S.,& Petrović, S.. (2016). Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts. in Journal of Supercritical Fluids
Elsevier Science Bv, Amsterdam., 110, 117-125.
https://doi.org/10.1016/j.supflu.2016.01.001
Petrović NV, Petrović SS, Džamić AM, Ćirić AD, Ristić MS, Milovanović S, Petrović S. Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts. in Journal of Supercritical Fluids. 2016;110:117-125.
doi:10.1016/j.supflu.2016.01.001 .
Petrović, Nada V., Petrović, Slobodan S., Džamić, Ana M., Ćirić, Ana D., Ristić, Mihailo S., Milovanović, Stoja, Petrović, Slobodan, "Chemical composition, antioxidant and antimicrobial activity of Thymus praecox supercritical extracts" in Journal of Supercritical Fluids, 110 (2016):117-125,
https://doi.org/10.1016/j.supflu.2016.01.001 . .
