There is a great technological interest in synthesis of lanthanide doped upconverting nanoparticles with specific morphological characteristics and efficient luminescence response suitable for biomedical use [1]. A conventional approach for generation of such particles comprises decomposition of organometallic compoundsin an oxygen-free environment and additional ligand exchange [2,3]. The biocompatible and water soluble NaYF4:Yb,Er"Chitosane particles used in this study were synthesized through facile one-pot hydrothermal synthesis and were characterized using X-ray powder diffraction (XRPD), Fourier-transform infrared (FTIR) spectroscopy, field emission scanning and transmission electron microscopy (FESEM and TEM) and photoluminesce measurement (PL). Due to the presence of the amino groups at their surface these particles exhibit excellent hydrophilic properties and low cytotoxicity against human gingival fibroblasts (HGF), which was proven by MTT assay. Furthermore, upon 980 nm lase...r irradiation the as-prepared particles were successfully used for in-vitro visualization of the primary cell cultures of head and neck squamous carcinoma cells (HNSCC). In a NaYF4:Yb,Er phase upconversion is enabled by the sequential absorption of two or more near-infrared photons by Yb3+ and subsequent energy transfer to the long-lived metastable electron states of Er3+ which produces luminescence emission at visible spectra after relaxation.
TY - CONF
AU - Dinić, Ivana
AU - Djukić-Vuković, Aleksandra
AU - Mojović, Ljiljana
AU - Nikolić, Marko G.
AU - Rabasović, Mihailo D.
AU - Krmpot, Aleksandar
AU - Milošević, Olivera
AU - Mančić, Lidija
PY - 2017
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3486
AB - There is a great technological interest in synthesis of lanthanide doped upconverting nanoparticles with specific morphological characteristics and efficient luminescence response suitable for biomedical use [1]. A conventional approach for generation of such particles comprises decomposition of organometallic compoundsin an oxygen-free environment and additional ligand exchange [2,3]. The biocompatible and water soluble NaYF4:Yb,Er"Chitosane particles used in this study were synthesized through facile one-pot hydrothermal synthesis and were characterized using X-ray powder diffraction (XRPD), Fourier-transform infrared (FTIR) spectroscopy, field emission scanning and transmission electron microscopy (FESEM and TEM) and photoluminesce measurement (PL). Due to the presence of the amino groups at their surface these particles exhibit excellent hydrophilic properties and low cytotoxicity against human gingival fibroblasts (HGF), which was proven by MTT assay. Furthermore, upon 980 nm laser irradiation the as-prepared particles were successfully used for in-vitro visualization of the primary cell cultures of head and neck squamous carcinoma cells (HNSCC). In a NaYF4:Yb,Er phase upconversion is enabled by the sequential absorption of two or more near-infrared photons by Yb3+ and subsequent energy transfer to the long-lived metastable electron states of Er3+ which produces luminescence emission at visible spectra after relaxation.
PB - Belgrade : Institute of Physics Belgrade
C3 - Abstracts of Tutorial, Keynote, Invited Lectures, Progress Reports and Contributed Papers of the Six
T1 - One-step synthesis of NIR-responsive NaYF4:Yb,Er"Chitosane nanoparticles for biomedical application
EP - 81
SP - 81
UR - https://hdl.handle.net/21.15107/rcub_technorep_3486
ER -
@conference{
author = "Dinić, Ivana and Djukić-Vuković, Aleksandra and Mojović, Ljiljana and Nikolić, Marko G. and Rabasović, Mihailo D. and Krmpot, Aleksandar and Milošević, Olivera and Mančić, Lidija",
year = "2017",
abstract = "There is a great technological interest in synthesis of lanthanide doped upconverting nanoparticles with specific morphological characteristics and efficient luminescence response suitable for biomedical use [1]. A conventional approach for generation of such particles comprises decomposition of organometallic compoundsin an oxygen-free environment and additional ligand exchange [2,3]. The biocompatible and water soluble NaYF4:Yb,Er"Chitosane particles used in this study were synthesized through facile one-pot hydrothermal synthesis and were characterized using X-ray powder diffraction (XRPD), Fourier-transform infrared (FTIR) spectroscopy, field emission scanning and transmission electron microscopy (FESEM and TEM) and photoluminesce measurement (PL). Due to the presence of the amino groups at their surface these particles exhibit excellent hydrophilic properties and low cytotoxicity against human gingival fibroblasts (HGF), which was proven by MTT assay. Furthermore, upon 980 nm laser irradiation the as-prepared particles were successfully used for in-vitro visualization of the primary cell cultures of head and neck squamous carcinoma cells (HNSCC). In a NaYF4:Yb,Er phase upconversion is enabled by the sequential absorption of two or more near-infrared photons by Yb3+ and subsequent energy transfer to the long-lived metastable electron states of Er3+ which produces luminescence emission at visible spectra after relaxation.",
publisher = "Belgrade : Institute of Physics Belgrade",
journal = "Abstracts of Tutorial, Keynote, Invited Lectures, Progress Reports and Contributed Papers of the Six",
title = "One-step synthesis of NIR-responsive NaYF4:Yb,Er"Chitosane nanoparticles for biomedical application",
pages = "81-81",
url = "https://hdl.handle.net/21.15107/rcub_technorep_3486"
}
Dinić, I., Djukić-Vuković, A., Mojović, L., Nikolić, M. G., Rabasović, M. D., Krmpot, A., Milošević, O.,& Mančić, L.. (2017). One-step synthesis of NIR-responsive NaYF4:Yb,Er"Chitosane nanoparticles for biomedical application. in Abstracts of Tutorial, Keynote, Invited Lectures, Progress Reports and Contributed Papers of the Six
Belgrade : Institute of Physics Belgrade., 81-81.
https://hdl.handle.net/21.15107/rcub_technorep_3486
Dinić I, Djukić-Vuković A, Mojović L, Nikolić MG, Rabasović MD, Krmpot A, Milošević O, Mančić L. One-step synthesis of NIR-responsive NaYF4:Yb,Er"Chitosane nanoparticles for biomedical application. in Abstracts of Tutorial, Keynote, Invited Lectures, Progress Reports and Contributed Papers of the Six. 2017;:81-81.
https://hdl.handle.net/21.15107/rcub_technorep_3486 .
Dinić, Ivana, Djukić-Vuković, Aleksandra, Mojović, Ljiljana, Nikolić, Marko G., Rabasović, Mihailo D., Krmpot, Aleksandar, Milošević, Olivera, Mančić, Lidija, "One-step synthesis of NIR-responsive NaYF4:Yb,Er"Chitosane nanoparticles for biomedical application" in Abstracts of Tutorial, Keynote, Invited Lectures, Progress Reports and Contributed Papers of the Six (2017):81-81,
https://hdl.handle.net/21.15107/rcub_technorep_3486 .
