TechnoRep - Faculty of Technology and Metallurgy Repository
University of Belgrade - Faculty of Technology and Metallurgy
    • English
    • Српски
    • Српски (Serbia)
  • English 
    • English
    • Serbian (Cyrillic)
    • Serbian (Latin)
  • Login
View Item 
  •   TechnoRep
  • Tehnološko-metalurški fakultet
  • Radovi istraživača / Researchers’ publications (TMF)
  • View Item
  •   TechnoRep
  • Tehnološko-metalurški fakultet
  • Radovi istraživača / Researchers’ publications (TMF)
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Gut microbiota and its role in human health

Thumbnail
2018
453-1957-1-CE.PDF (383.2Kb)
Authors
Rajilić-Stojanović, Mirjana
Article (Published version)
Metadata
Show full item record
Abstract
Humans live in a close association with a complex microbial ecosystem that is collectively termed microbiota. Microbiota is concentrated in the last part of the gastrointestinal tract, where it ferments undigested food residues and produces various metabolites that have a systemic influence on human physiology. The composition of microbiota is influenced by genetic and environmental factors that shape a unique ecosystem in each human. Despite considerable compositional variations, the functional output of the ecosystem is highly similar in all healthy individuals. Although it is still not possible to define normal microbiota, comparisons between patients suffering from a number of chronic diseases with unknown etiology and controls have shown that patients have specific, dysbiotic microbiota composition. While it still remains to be determined if the microbiota dysbiosis is an etiological factor or a consequence of a disease, these findings have initiated intensive microbiota research.... Numerous proven functions of microbiota include contribution to the digestion, synthesis of essential metabolites (vitamins and amino acids) and the intensive crosstalk with the immune, the endocrine and the nervous system. Even though this field of research is still in an early stage, it is clear that microbial metabolites can have various effects on humans including direct beneficial effect, toxicity, but also more subtle interactions since microbial products can act as immune regulating or neuro-signaling molecules. The complex network of bidirectional interactions between microbiota and humans is unexplored but highly potent for development of novel strategies to preserve and improve health.

Keywords:
Composition / Dysbiosis / Human health / Microbiota
Source:
Psihologijske Teme, 2018, 27, 1, 17-32
Publisher:
  • University of Rijeka

DOI: 10.31820/pt.27.1.2

ISSN: 1332-0742

PubMed:

Scopus: 2-s2.0-85046731612
[ Google Scholar ]
URI
http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3762
Collections
  • Radovi istraživača / Researchers’ publications (TMF)
Institution/Community
Tehnološko-metalurški fakultet
TY  - JOUR
AU  - Rajilić-Stojanović, Mirjana
PY  - 2018
UR  - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3762
AB  - Humans live in a close association with a complex microbial ecosystem that is collectively termed microbiota. Microbiota is concentrated in the last part of the gastrointestinal tract, where it ferments undigested food residues and produces various metabolites that have a systemic influence on human physiology. The composition of microbiota is influenced by genetic and environmental factors that shape a unique ecosystem in each human. Despite considerable compositional variations, the functional output of the ecosystem is highly similar in all healthy individuals. Although it is still not possible to define normal microbiota, comparisons between patients suffering from a number of chronic diseases with unknown etiology and controls have shown that patients have specific, dysbiotic microbiota composition. While it still remains to be determined if the microbiota dysbiosis is an etiological factor or a consequence of a disease, these findings have initiated intensive microbiota research. Numerous proven functions of microbiota include contribution to the digestion, synthesis of essential metabolites (vitamins and amino acids) and the intensive crosstalk with the immune, the endocrine and the nervous system. Even though this field of research is still in an early stage, it is clear that microbial metabolites can have various effects on humans including direct beneficial effect, toxicity, but also more subtle interactions since microbial products can act as immune regulating or neuro-signaling molecules. The complex network of bidirectional interactions between microbiota and humans is unexplored but highly potent for development of novel strategies to preserve and improve health.
PB  - University of Rijeka
T2  - Psihologijske Teme
T1  - Gut microbiota and its role in human health
EP  - 32
IS  - 1
SP  - 17
VL  - 27
DO  - 10.31820/pt.27.1.2
ER  - 
@article{
author = "Rajilić-Stojanović, Mirjana",
year = "2018",
abstract = "Humans live in a close association with a complex microbial ecosystem that is collectively termed microbiota. Microbiota is concentrated in the last part of the gastrointestinal tract, where it ferments undigested food residues and produces various metabolites that have a systemic influence on human physiology. The composition of microbiota is influenced by genetic and environmental factors that shape a unique ecosystem in each human. Despite considerable compositional variations, the functional output of the ecosystem is highly similar in all healthy individuals. Although it is still not possible to define normal microbiota, comparisons between patients suffering from a number of chronic diseases with unknown etiology and controls have shown that patients have specific, dysbiotic microbiota composition. While it still remains to be determined if the microbiota dysbiosis is an etiological factor or a consequence of a disease, these findings have initiated intensive microbiota research. Numerous proven functions of microbiota include contribution to the digestion, synthesis of essential metabolites (vitamins and amino acids) and the intensive crosstalk with the immune, the endocrine and the nervous system. Even though this field of research is still in an early stage, it is clear that microbial metabolites can have various effects on humans including direct beneficial effect, toxicity, but also more subtle interactions since microbial products can act as immune regulating or neuro-signaling molecules. The complex network of bidirectional interactions between microbiota and humans is unexplored but highly potent for development of novel strategies to preserve and improve health.",
publisher = "University of Rijeka",
journal = "Psihologijske Teme",
title = "Gut microbiota and its role in human health",
pages = "32-17",
number = "1",
volume = "27",
doi = "10.31820/pt.27.1.2"
}
Rajilić-Stojanović, M.. (2018). Gut microbiota and its role in human health. in Psihologijske Teme
University of Rijeka., 27(1), 17-32.
https://doi.org/10.31820/pt.27.1.2
Rajilić-Stojanović M. Gut microbiota and its role in human health. in Psihologijske Teme. 2018;27(1):17-32.
doi:10.31820/pt.27.1.2 .
Rajilić-Stojanović, Mirjana, "Gut microbiota and its role in human health" in Psihologijske Teme, 27, no. 1 (2018):17-32,
https://doi.org/10.31820/pt.27.1.2 . .

DSpace software copyright © 2002-2015  DuraSpace
About TechnoRep | Send Feedback

OpenAIRERCUB
 

 

All of DSpaceInstitutions/communitiesAuthorsTitlesSubjectsThis institutionAuthorsTitlesSubjects

Statistics

View Usage Statistics

DSpace software copyright © 2002-2015  DuraSpace
About TechnoRep | Send Feedback

OpenAIRERCUB