Scaffolds based on chitosan (CTS), collagen (Coll), and glycosaminoglycans (GAGs) cross-linked by sodium alginate (SA) were obtained with the use of the freeze-drying method. They were characterized by different analyses, e.g. infrared spectroscopy, SEM images and differential scanning calorimetry. Furthermore, bio-mechanical properties of the scaffolds were determined in a biomimetic bioreactor. The results showed that the scaffolds based on chitosan, collagen, and glycosaminoglycans cross-linked by sodium alginate are stable in aqueous environment. The infrared spectroscopy analysis showed the hydrogen bond formation between polymers. Scaffolds presented open-pores structures even after a 3-day long analysis in a perfusion bioreactor. The obtained results indicate that the addition of sodium alginate slightly modified biomechanical properties.
TY - JOUR
AU - Kaczmarek, B.
AU - Sionkowska, A.
AU - Stojkovska, Jasmina
PY - 2018
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/3866
AB - Scaffolds based on chitosan (CTS), collagen (Coll), and glycosaminoglycans (GAGs) cross-linked by sodium alginate (SA) were obtained with the use of the freeze-drying method. They were characterized by different analyses, e.g. infrared spectroscopy, SEM images and differential scanning calorimetry. Furthermore, bio-mechanical properties of the scaffolds were determined in a biomimetic bioreactor. The results showed that the scaffolds based on chitosan, collagen, and glycosaminoglycans cross-linked by sodium alginate are stable in aqueous environment. The infrared spectroscopy analysis showed the hydrogen bond formation between polymers. Scaffolds presented open-pores structures even after a 3-day long analysis in a perfusion bioreactor. The obtained results indicate that the addition of sodium alginate slightly modified biomechanical properties.
PB - Elsevier Sci Ltd, Oxford
T2 - Polymer Testing
T1 - Characterization of scaffolds based on chitosan and collagen with glycosaminoglycans and sodium alginate addition
EP - 232
SP - 229
VL - 68
DO - 10.1016/j.polymertesting.2018.04.021
ER -
@article{
author = "Kaczmarek, B. and Sionkowska, A. and Stojkovska, Jasmina",
year = "2018",
abstract = "Scaffolds based on chitosan (CTS), collagen (Coll), and glycosaminoglycans (GAGs) cross-linked by sodium alginate (SA) were obtained with the use of the freeze-drying method. They were characterized by different analyses, e.g. infrared spectroscopy, SEM images and differential scanning calorimetry. Furthermore, bio-mechanical properties of the scaffolds were determined in a biomimetic bioreactor. The results showed that the scaffolds based on chitosan, collagen, and glycosaminoglycans cross-linked by sodium alginate are stable in aqueous environment. The infrared spectroscopy analysis showed the hydrogen bond formation between polymers. Scaffolds presented open-pores structures even after a 3-day long analysis in a perfusion bioreactor. The obtained results indicate that the addition of sodium alginate slightly modified biomechanical properties.",
publisher = "Elsevier Sci Ltd, Oxford",
journal = "Polymer Testing",
title = "Characterization of scaffolds based on chitosan and collagen with glycosaminoglycans and sodium alginate addition",
pages = "232-229",
volume = "68",
doi = "10.1016/j.polymertesting.2018.04.021"
}
Kaczmarek, B., Sionkowska, A.,& Stojkovska, J.. (2018). Characterization of scaffolds based on chitosan and collagen with glycosaminoglycans and sodium alginate addition. in Polymer Testing
Elsevier Sci Ltd, Oxford., 68, 229-232.
https://doi.org/10.1016/j.polymertesting.2018.04.021
Kaczmarek B, Sionkowska A, Stojkovska J. Characterization of scaffolds based on chitosan and collagen with glycosaminoglycans and sodium alginate addition. in Polymer Testing. 2018;68:229-232.
doi:10.1016/j.polymertesting.2018.04.021 .
Kaczmarek, B., Sionkowska, A., Stojkovska, Jasmina, "Characterization of scaffolds based on chitosan and collagen with glycosaminoglycans and sodium alginate addition" in Polymer Testing, 68 (2018):229-232,
https://doi.org/10.1016/j.polymertesting.2018.04.021 . .
