Electrochemical behavior of sildenafil citrate (SC) at gold and cystein (Cys) modified gold electrode (AulCys) in 0.1 M H2SO4 was investigated by cyclic voltammetry (CV) and by square wave voltammetry (SWV). Effect of scan rate on the CVs of SC standard was performed in order to examine the mode of transport and irreversibility of process. SC as standard is determined by SWV in acid solution at Au electrode in a range: 10(-3), 10(-2) 0.1, 0.5, 1 mu M and on Au/Cys in a range: 10(-3), 10(-2) 0.05, 0.1 mu M. The presence of Cys causes two-time larger peak currents and shifting of the incipient potential of the SC oxidation to 0.1 V in negative direction. In investigated range of concentration of SC standard in acid solution on modified and unmodified Au electrodes SWV method have excellent linear regression coefficient with value 0.997 promoting SWV for reliable determination of SC.
TY - JOUR
AU - Lović, Jelena
AU - Trišović, Nemanja
AU - Antanasijević, Jelena
AU - Avramov-Ivić, Milka
PY - 2018
UR - http://TechnoRep.tmf.bg.ac.rs/handle/123456789/4009
AB - Electrochemical behavior of sildenafil citrate (SC) at gold and cystein (Cys) modified gold electrode (AulCys) in 0.1 M H2SO4 was investigated by cyclic voltammetry (CV) and by square wave voltammetry (SWV). Effect of scan rate on the CVs of SC standard was performed in order to examine the mode of transport and irreversibility of process. SC as standard is determined by SWV in acid solution at Au electrode in a range: 10(-3), 10(-2) 0.1, 0.5, 1 mu M and on Au/Cys in a range: 10(-3), 10(-2) 0.05, 0.1 mu M. The presence of Cys causes two-time larger peak currents and shifting of the incipient potential of the SC oxidation to 0.1 V in negative direction. In investigated range of concentration of SC standard in acid solution on modified and unmodified Au electrodes SWV method have excellent linear regression coefficient with value 0.997 promoting SWV for reliable determination of SC.
PB - Int Assoc Physical Chemists-Iapc, Zagreb
T2 - Journal of Electrochemical Science and Engineering
T1 - Electrochemical behaviour of sildenafil citrate at gold and cystein modified gold electrode in acid solution
EP - 170
IS - 2
SP - 163
VL - 8
DO - 10.5599/jese.481
ER -
@article{
author = "Lović, Jelena and Trišović, Nemanja and Antanasijević, Jelena and Avramov-Ivić, Milka",
year = "2018",
abstract = "Electrochemical behavior of sildenafil citrate (SC) at gold and cystein (Cys) modified gold electrode (AulCys) in 0.1 M H2SO4 was investigated by cyclic voltammetry (CV) and by square wave voltammetry (SWV). Effect of scan rate on the CVs of SC standard was performed in order to examine the mode of transport and irreversibility of process. SC as standard is determined by SWV in acid solution at Au electrode in a range: 10(-3), 10(-2) 0.1, 0.5, 1 mu M and on Au/Cys in a range: 10(-3), 10(-2) 0.05, 0.1 mu M. The presence of Cys causes two-time larger peak currents and shifting of the incipient potential of the SC oxidation to 0.1 V in negative direction. In investigated range of concentration of SC standard in acid solution on modified and unmodified Au electrodes SWV method have excellent linear regression coefficient with value 0.997 promoting SWV for reliable determination of SC.",
publisher = "Int Assoc Physical Chemists-Iapc, Zagreb",
journal = "Journal of Electrochemical Science and Engineering",
title = "Electrochemical behaviour of sildenafil citrate at gold and cystein modified gold electrode in acid solution",
pages = "170-163",
number = "2",
volume = "8",
doi = "10.5599/jese.481"
}
Lović, J., Trišović, N., Antanasijević, J.,& Avramov-Ivić, M.. (2018). Electrochemical behaviour of sildenafil citrate at gold and cystein modified gold electrode in acid solution. in Journal of Electrochemical Science and Engineering
Int Assoc Physical Chemists-Iapc, Zagreb., 8(2), 163-170.
https://doi.org/10.5599/jese.481
Lović J, Trišović N, Antanasijević J, Avramov-Ivić M. Electrochemical behaviour of sildenafil citrate at gold and cystein modified gold electrode in acid solution. in Journal of Electrochemical Science and Engineering. 2018;8(2):163-170.
doi:10.5599/jese.481 .
Lović, Jelena, Trišović, Nemanja, Antanasijević, Jelena, Avramov-Ivić, Milka, "Electrochemical behaviour of sildenafil citrate at gold and cystein modified gold electrode in acid solution" in Journal of Electrochemical Science and Engineering, 8, no. 2 (2018):163-170,
https://doi.org/10.5599/jese.481 . .
